Abramson Cancer Center at Penn Medicine

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Abramson Cancer Center at Penn Medicine sits in the top decile of US sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count).

402 total trials 74 currently recruiting 235 completed early-phase tilt top decile by trial count

Abramson Cancer Center at Penn Medicine: 402 sponsored US clinical trials, 74 recruiting.

Abramson Cancer Center at Penn Medicine sponsors 402 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 235 completed. 3 of these trials are in Phase 3-4 (later-stage) and 175 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 20 trials.

Top-decile sponsor footprint

Abramson Cancer Center at Penn Medicine ranks in the top decile of sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

235 of 280 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

402 total, page 3 of 9

ACTIVE NOT RECRUITING Phase 2

Adjuvant Treatment Determined By Pathological Response To Neoadjvuant Nivolumab

NCT04013854

ACTIVE NOT RECRUITING Phase 2

Niraparib/TTFields in GBM

NCT04221503

ACTIVE NOT RECRUITING

BRCA1/2 Flu Vaccine

NCT04499534

ACTIVE NOT RECRUITING NA

Ostomy Rural Telehealth Training Cancer Survivors

NCT03913715

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma

NCT03757689

ACTIVE NOT RECRUITING NA

TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck

NCT03729518

ACTIVE NOT RECRUITING NA

Personalized Radiation Therapy for GBM

NCT03477513

ACTIVE NOT RECRUITING Early Phase 1

Evaluating in Vivo PARP-1 Expression With 18F-FluorThanatrace Positron Emission Tomography (PET/CT) in Prostate Cancer

NCT03334500

ACTIVE NOT RECRUITING

AYA STEPS RCT: AYA Self-Management Via Texting, Education & Plans for Survivors

NCT03363711

ACTIVE NOT RECRUITING Phase 1

Evaluating in Vivo PARP-1 Expression With 18F-FluorThanatrace Positron Emission Tomography (PET/CT) in Breast Cancer

NCT03083288

ACTIVE NOT RECRUITING Phase 2

CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine, EVErolimus or the Combination for Prevention of Recurrent Breast Cancer

NCT03032406

ACTIVE NOT RECRUITING NA

Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial

NCT02603341

ACTIVE NOT RECRUITING Phase 1

A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer

NCT02207465

ACTIVE NOT RECRUITING Phase 2

Phase II Trial of Radical Pleurectomy With or Without Intraoperative PDT for Malignant Pleural Mesothelioma

NCT02153229

ACTIVE NOT RECRUITING Phase 1

Dose Escalation of Neoadjuvant Proton Beam Radiotherapy With Concurrent Chemotherapy in Locally Advanced Esophageal Cancer

NCT02213497

ACTIVE NOT RECRUITING

Breast Cancer 2-PREVENT Translational Center of Excellence (TCE) - Metastatic Markers of Recurrent Tumor Phenotype for Breast Cancer

NCT02530008

ACTIVE NOT RECRUITING NA

TACE With or Without SBRT as Bridging Therapy for Pre-transplant HCC Patients

NCT01918683

ACTIVE NOT RECRUITING

The Breast Program - Translational Cancer Resource

NCT02798341

ACTIVE NOT RECRUITING

Prospective Follow-up of Outcomes in Patients Receiving Photodynamic Therapy for Neoplastic Diseases

NCT02159742

ACTIVE NOT RECRUITING

Mild Hypofractionation With Proton Therapy or IMRT for Intermediate-Risk Prostate Cancer

NCT01352429

NOT YET RECRUITING Phase 2

Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma

NCT07059611

NOT YET RECRUITING NA

Consolidative Metastasis and Primary Directed Therapy (MPDT) for Renal Cell Carcinoma (RCC)

NCT06770855

COMPLETED NA

Evaluating a Bidirectional Priming Intervention for Goals-of-care Communication in Oncology

NCT06955468

COMPLETED NA

Nudge Strategies for DPYD Testing in Patients With Gastrointestinal Cancers Treated With Fluoropyrimidines

NCT06559462

COMPLETED NA

Virtual Reality to Promote Relaxation Prior to Simulation

NCT06318338

COMPLETED NA

Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender Minority Teens

NCT06308081

COMPLETED NA

Patient Ambassador

NCT06711380

COMPLETED NA

Increasing Screening for Cancer Using EHR-Nudges

NCT06177795

COMPLETED NA

Behavioral Economic Strategies to Improve PRO Adherence

NCT06013176

COMPLETED NA

Comparison of Apixaban Versus Enoxaparin

NCT06243510

COMPLETED NA

Improving Utilization of Supplemental Breast MRI Screening for Women With Extremely Dense Breasts

NCT05787249

COMPLETED NA

Staying Healthy With Follow-up Care: A Mobile Chatbot Feasibility Study for AYA Cancer Survivors

NCT05863702

COMPLETED NA

Lung Cancer Screening Eligibility Assessment

NCT06133816

TERMINATED NA

Telehealth Based Synchronous Navigation to Improve Molecularly-Informed Care for Patients With Lung Cancer

NCT05790460

COMPLETED NA

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

NCT05721326

COMPLETED

Using Surveys to Examine the Association of Exposure to ML Mortality Risk Predictions With Medical Oncologists' Prognostic Accuracy and Decision-making

NCT06463977

COMPLETED NA

Community Support Program for Lung Cancer Screening

NCT06207435

COMPLETED NA

Shared Decision-making and Colorectal Cancer Screening

NCT04748380

COMPLETED NA

Project PLUS Lung Cancer Screening Promotion

NCT05937399

COMPLETED NA

Predictive Analytics and Behavioral Nudges to Improve Palliative Care in Advanced Cancer

NCT05590962

COMPLETED

Head Stabilization of Healthy Volunteers

NCT07116759

COMPLETED NA

Project RESIST: Evaluating the Effects of Anti-smoking Inoculation Messages Among Young Adult Sexual Minority Women

NCT05499520

COMPLETED NA

Improving Tobacco Treatment Rates for Cancer Patients Who Smoke

NCT04738643

COMPLETED NA

Physical Activity in Rectal Cancer Survivors

NCT06435975

COMPLETED NA

Mailed FIT Outreach 2022

NCT05341622

COMPLETED NA

Behavioral Nudges to Improve Palliative Care Utilization in Advanced Cancer

NCT05365997

COMPLETED NA

RCT of Strategies to Augment Physical Activity in Black and Hispanic Breast and Prostate Cancer Survivors (ALLSTAR)

NCT05176756

COMPLETED

Improving Colorectal Cancer Screening in Racially Diverse Zip Codes Using Navigation and Machine Learning (PCSNaP)

NCT05383976

COMPLETED NA

Acute Effects of Cigarette Packaging and Charcoal Filtration on Perceptions, Use Behaviors, and Harm Exposure

NCT05157048

COMPLETED Early Phase 1

Zr89 + PET Companion Trial

NCT05279027

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Phase Distribution

PhaseTrial count
Phase 1 113
Phase 2 62
Phase 3 1
Phase 4 2

What is open in the Abramson Cancer Center at Penn Medicine pipeline

74 recruiting of 402 indexed (18% open); 235 completed (58%).

Phase mix: 3 late (III/IV) vs 175 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (20 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Abramson Cancer Center at Penn Medicine: open-pipeline peers nationwide

Peers matched on 402 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 10%15%20%25% Total trials Recruiting share Abramson Cancer Center at Penn MedicineCase Comprehensive Cancer CenterUniversity of NebraskaTakedaUniversity of Kansas Medical CenterUniversity of Maryland, BaltimoreHenry Ford Health SystemNew York Institute of TechnologyUniversity of California, San Diego
Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 402 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Abramson Cancer Center at Penn Medicine page

402 registered trials is a research-attention snapshot, not an endorsement of Abramson Cancer Center at Penn Medicine or any single study.

  • 74 of Abramson Cancer Center at Penn Medicine's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Abramson Cancer Center at Penn Medicine studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Abramson Cancer Center at Penn Medicine pipeline card: 402 registered trials from official public datasets.Report a data error.