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NCT02603341 · ClinicalTrials.gov registry record · NA
Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial
A NA study of Breast Cancer, sponsored by Abramson Cancer Center at Penn Medicine.
- Active
- Registry status
- NA
- Development phase
- 1,238
- Enrollment target
- 20
- Study locations
NCT02603341: Active NA study of Breast Cancer, sponsored by Abramson Cancer Center at Penn Medicine.
NCT02603341 is a NA study of Breast Cancer that is active but no longer recruiting, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 1,238 participants, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (56% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02603341, a NA study of Breast Cancer, is active but no longer recruiting, sponsored by Abramson Cancer Center at Penn Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 1,238 participants
- Enrollment target
- 20
- Study locations
Study Summary
A pragmatic randomized clinical trial of patients with locally advanced breast cancer randomized to either proton or photon therapy and followed longitudinally for cardiovascular morbidity and mortality, health-related quality of life, and cancer control outcomes. Quality of life is the outcome measure for the estimated primary completion date of December, 2024, www.radcomp.org.
Primary Outcome
Compare the effectiveness of proton vs. photon therapy in reducing major cardiovascular events (MCE), defined as atherosclerotic coronary heart disease or other heart disease death, myocardial infarction, coronary revascularization, or hospitalization for major cardiovascular event (heart failure, valvular disease, arrhythmia, or unstable angina).
Conditions Studied
Interventions
- RADIATION Proton
- RADIATION Photon
Study Locations (20)
Florida
- University of Miami Sylvester Cancer Center at Coral Gables - Coral Gables
- University of Miami Sylvester Cancer Center - Deerfield - Deerfield Beach
- University of Florida Health - Gainesville
- University of Florida Health Proton Therapy Institute - Jacksonville
- University of Miami Sylvester Cancer Center - Miami
- Miami Cancer Insititute - Miami
- Orlando Health - Orlando
Maryland
- University of Maryland - Baltimore
- Johns Hopkins - Baltimore
Massachusetts
- Massachusetts General Hospital - Boston
- Mass General/North Shore Cancer Center - Danvers
Michigan
- McLaren Proton Therapy - Flint
- William Beaumont - Royal Oak
Alabama
- University of Alabama - Birmingham
Arizona
- Mayo Clinic-Arizona - Phoenix
California
- UC San Diego - San Diego
District of Columbia
- Georgetown University Medical Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,238 participants |
| Start Date | 2016-04-06 |
| Est. Completion | 2036-11 |
| Phase | NA |
What the registry record for NCT02603341 still lists
NCT02603341 is an interventional study that assigns participants to a tested intervention. Its 1,238 participants enrollment target places it among the larger protocols in the corpus, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (56% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Proton is the first listed.
NCT02603341 names 20 study sites across 11 states, led by Florida, Maryland, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT02603341 about?
NCT02603341 is a clinical study titled "Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial". A pragmatic randomized clinical trial of patients with locally advanced breast cancer randomized to either proton or photon therapy and followed longitudinally for cardiovascular morbidity and mortality, health-related quality of life, and cancer control outcomes. Quality of life is the outcome meas...
What is the current status of trial NCT02603341?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 1,238 participants. The study started on 2016-04-06. Estimated completion is 2036-11.
What conditions does trial NCT02603341 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT02603341?
The interventions under investigation include: Proton (RADIATION), Photon (RADIATION).
Who is sponsoring clinical trial NCT02603341?
This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02603341 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02603341's enrollment target sits among peer trials
1,238 101st of 1224 higher than 1,124 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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