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NCT03729518 · ClinicalTrials.gov registry record · NA

TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck

A NA study of Squamous Cell Carcinoma and Human Papilloma Virus, sponsored by Abramson Cancer Center at Penn Medicine.

Active
Registry status
NA
Development phase
150
Enrollment target
1
Study location

NCT03729518 is a NA study of Squamous Cell Carcinoma and Human Papilloma Virus that is active but no longer recruiting, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 150 participants, above the 101-participant average among 47 other Squamous Cell Carcinoma trials with a reported enrollment target (49% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT03729518, a NA study of Squamous Cell Carcinoma and Human Papilloma Virus, is active but no longer recruiting, sponsored by Abramson Cancer Center at Penn Medicine.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
150 participants
Enrollment target
1
Study location

Study Summary

This is a single-arm Phase II study of adjuvant radiation for locally advanced p16+ oropharyngeal squamous cell carcinoma. The main purpose of this research is to determine the likelihood of cancer growing back in the throat or in the neck two years after completion of radiation if lower doses of radiation are used to a smaller area of the head and neck region than is currently used in standard of care.

Interventions

  • RADIATION Radiation Therapy (IMRT or IMPT)

Study Locations (1)

Pennsylvania

  • University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2018-10-11
Est. Completion 2026-05
Phase NA

What the Registry Record Tells You About NCT03729518

The ClinicalTrials.gov registry entry for NCT03729518 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 101-participant average among 47 other Squamous Cell Carcinoma trials with a reported enrollment target (49% higher). The listed sponsor is Abramson Cancer Center at Penn Medicine, which has 402 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Squamous Cell Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which Radiation Therapy (IMRT or IMPT) is the first listed.

NCT03729518 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT03729518 about?

NCT03729518 is a clinical study titled "TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck". This is a single-arm Phase II study of adjuvant radiation for locally advanced p16+ oropharyngeal squamous cell carcinoma. The main purpose of this research is to determine the likelihood of cancer growing back in the throat or in the neck two years after completion of radiation if lower doses of ra...

What is the current status of trial NCT03729518?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2018-10-11. Estimated completion is 2026-05.

What conditions does trial NCT03729518 study?

This clinical trial studies the following conditions: Squamous Cell Carcinoma, Human Papilloma Virus, Oropharyngeal Cancer.

What interventions are being tested in trial NCT03729518?

The interventions under investigation include: Radiation Therapy (IMRT or IMPT) (RADIATION).

Who is sponsoring clinical trial NCT03729518?

This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03729518 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.