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NCT05182229 · ClinicalTrials.gov registry record · NA
Comparing Two Ways to Manage Head and Neck Lymphedema
A NA study of Head and Neck Cancer and Lymphedema, sponsored by Abramson Cancer Center at Penn Medicine.
- Recruiting
- Registry status
- NA
- Development phase
- 300
- Enrollment target
- 6
- Study locations
NCT05182229: Recruiting NA study of Head and Neck Cancer and Lymphedema, sponsored by Abramson Cancer Center at Penn Medicine.
NCT05182229 is a NA study of Head and Neck Cancer and Lymphedema that is actively recruiting participants, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 300 participants, above the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (15% higher). The trial reports 6 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05182229, a NA study of Head and Neck Cancer and Lymphedema, is actively recruiting participants, sponsored by Abramson Cancer Center at Penn Medicine.
- RECRUITING
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
- 6
- Study locations
Study Summary
This randomized clinical trial aims to compare clinic-based CDT and home-based (a hybrid model) CDT on changes in the severity of lymphedema, symptom burden, functional status, and healthcare utilization in HNC survivors with lymphedema.
Primary Outcome
Compare the effects of clinic-based and home-based CDT on changes in the severity of lymphedema. This outcome measure will be assessed via Head and Neck - External Lymphedema and Fibrosis Assessment Criteria (HN-LEF Assessment Criteria).
Conditions Studied
Interventions
- OTHER Home-based (a hybrid model) CDT
- OTHER Clinic-based CDT
Study Locations (6)
Pennsylvania
- University of Pennsylvania - Philadelphia
- Jefferson Health - Philadelphia
- Jefferson Torresdale Hospital Jefferson Health - Philadelphia
- Temple University Hospital and Fox Chase Cancer Center - Philadelphia
- Asplundh Cancer Pavilion Jefferson Health - Willow Grove
New Jersey
- Jefferson Cherry Hospital Jefferson Health - Cherry Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2022-03-11 |
| Est. Completion | 2026-11-30 |
| Phase | NA |
What NCT05182229 shows while recruiting
NCT05182229 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (15% higher).
The record links to 2 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 2 interventions - of which Home-based (a hybrid model) CDT is the first listed.
NCT05182229 lists 6 locations in 2 states (Pennsylvania, New Jersey).
Frequently Asked Questions
What is clinical trial NCT05182229 about?
NCT05182229 is a clinical study titled "Comparing Two Ways to Manage Head and Neck Lymphedema". This randomized clinical trial aims to compare clinic-based CDT and home-based (a hybrid model) CDT on changes in the severity of lymphedema, symptom burden, functional status, and healthcare utilization in HNC survivors with lymphedema.
What is the current status of trial NCT05182229?
This trial is currently recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2022-03-11. Estimated completion is 2026-11-30.
What conditions does trial NCT05182229 study?
This clinical trial studies the following conditions: Head and Neck Cancer, Lymphedema.
What interventions are being tested in trial NCT05182229?
The interventions under investigation include: Home-based (a hybrid model) CDT (OTHER), Clinic-based CDT (OTHER).
Who is sponsoring clinical trial NCT05182229?
This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05182229 being conducted?
This trial has 6 study locations across New Jersey, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05182229's enrollment target sits among peer trials
300 35th of 250 higher than 214 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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