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NCT02241889 · ClinicalTrials.gov registry record · NA

Three-way, Cross-over Closed-loop Exercise Study

A NA study of Type 1 Diabetes, sponsored by Oregon Health and Science University.

Completed
Registry status
NA
Development phase
23
Enrollment target
1
Study location

NCT02241889: Completed NA study of Type 1 Diabetes, sponsored by Oregon Health and Science University.

NCT02241889 is a NA study of Type 1 Diabetes that has completed, run by Oregon Health and Science University. The registered enrollment target is 23 participants, below the 767-participant average among 198 other Type 1 Diabetes trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02241889, a NA study of Type 1 Diabetes, has completed, sponsored by Oregon Health and Science University.

COMPLETED
Registry status
NA
Development phase
23 participants
Enrollment target
1
Study location

Study Summary

Blood glucose control systems that utilize both insulin and glucagon to manage blood sugar are paving the way to revolutionize the management of this disease. The benefit of improved control of blood sugar levels compared to standard insulin pump therapy has already been demonstrated. However, the risk of low blood sugar in type 1 diabetes increases considerably during exercise. The investigators research group has shown that small doses of glucagon can prevent low blood sugar when used in a blood sugar control system in patients with type 1 diabetes. However, as insulin sensitivity changes occur very rapidly during exercise, the ability to recognize the onset of physical activity in order to appropriately adjust the insulin and glucagon delivery is vital to helping prevent exercise-induced hypoglycemia. The purpose of this study is to test how well a new modified blood sugar control system controls blood sugar during exercise compared to: 1) the current system without modifications and 2) standard insulin pump therapy.

Primary Outcome

Assess the percent of time that the Dexcom G4 or G4 Share reported sensor glucose values less than 70 mg/dl using Dexcom sensor downloads.

Conditions Studied

Interventions

  • DEVICE Insulin pump therapy
  • DEVICE Closed-loop Artificial Pancreas Controller

Study Locations (1)

Oregon

  • Oregon Health and Science University - Portland

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2015-01
Est. Completion 2015-09
Phase NA

What the finished NCT02241889 record still lists

NCT02241889 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 767-participant average among 198 other Type 1 Diabetes trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Type 1 Diabetes appearing as the primary indexed condition, and to 2 interventions - of which Insulin pump therapy is the first listed.

NCT02241889 reports a single indexed study location in Oregon.

Frequently Asked Questions

What is clinical trial NCT02241889 about?

NCT02241889 is a clinical study titled "Three-way, Cross-over Closed-loop Exercise Study". Blood glucose control systems that utilize both insulin and glucagon to manage blood sugar are paving the way to revolutionize the management of this disease. The benefit of improved control of blood sugar levels compared to standard insulin pump therapy has already been demonstrated. However, the r...

What is the current status of trial NCT02241889?

This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2015-01. Estimated completion is 2015-09.

What conditions does trial NCT02241889 study?

This clinical trial studies the following conditions: Type 1 Diabetes.

What interventions are being tested in trial NCT02241889?

The interventions under investigation include: Insulin pump therapy (DEVICE), Closed-loop Artificial Pancreas Controller (DEVICE).

Who is sponsoring clinical trial NCT02241889?

This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02241889 being conducted?

This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Type 1 Diabetes

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02241889's enrollment target sits among peer trials

23 149th of 198 higher than 50 of 198 other Type 1 Diabetes trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Type 1 Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02241889, the US trial registry maintained by the National Library of Medicine. NCT02241889 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.