Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,963 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,963 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Open enrollment, early-phase tilt
Stroke has 456 registered US clinical trials, 218 of them open to new participants right now, about 48% of the total.
- 218
- recruiting participants now
- 48%
- of trials open to enrollment
- 16
- in Phase 3-4 (later-stage)
- 27
- top sponsor: VA Office of Research and Development
Corpus placement: #9 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
-
Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
-
Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
-
Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 5 of 10
Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways
Peter C. Gerszten, MD
NCT07401186
Improving Stroke Motor Control With Non-invasive Brain Stimulation and Functional Electrical Stimulation
MetroHealth Medical Center
NCT03857529
Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment
University of Alabama at Birmingham
NCT05492513
CUped: An Approach to Motor Recovery Post-Stroke, Not Compensation
Marquette University
NCT06329765
Adaptive Hip Exoskeleton for Stroke Gait Enhancement
Georgia Institute of Technology
NCT05536739
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
Jorge Gonzalez-Martinez
NCT06303869
R3THA Rehabilitation Feasibility and Usability Study
Kessler Foundation
NCT06854978
EMG Controlled Device in Acute Rehabilitation After Acute Stroke
VA Office of Research and Development
NCT04599036
Evaluation of an Advanced Lower Extremity Neuroprostheses
Case Western Reserve University
NCT00623389
An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation
University of Pittsburgh
NCT04187131
Mobile Cognitive Behavioral Therapy for Stroke
Weill Medical College of Cornell University
NCT06689878
Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms
University of California, San Francisco
NCT02638701
Implant for Walking After Stroke
MetroHealth Medical Center
NCT05740540
VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration
Neuralink
NCT07224256
At-Home taVNS - Stroke Rehab
Medical University of South Carolina
NCT06616831
Passive Robots for Stroke Rehabilitation: A Feasibility Study
University of Michigan
NCT07218276
ECoG BMI for Motor and Speech Control
Karunesh Ganguly
NCT03698149
Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
Paradromics
NCT07357428
Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)
Anne Murray
NCT07224347
Genetic Testing of CYP2C19 in Prognostic Evaluation of Long-Term Major Adverse Cardiac and Vascular Events
University of Florida
NCT06855394
EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
Amgen
NCT05284747
ThRombectomy In Mild Ischemic Stroke With a Visible Intracranial veSsel Occlusion
University of Miami
NCT06778226
STROKE STAT (Stroke Severity-based Triage to Accelerate Treatment)
University of Alabama at Birmingham
NCT04978480
Sleep for Stroke Management and Recovery Trial
University of Michigan
NCT03812653
CHAMPION-AF Clinical Trial
Boston Scientific Corporation
NCT04394546
Amplatzer Amulet LAAO vs. NOAC
Abbott Medical Devices
NCT04226547
SIMPLAAFY Clinical Trial
Boston Scientific Corporation
NCT06521463
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis
University of Florida
NCT05047172
Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation
Anthos Therapeutics
NCT04755283
Genetic and Environmental Risk Factors for Hemorrhagic Stroke-GERFHS III
University of Cincinnati
NCT00930280
AMPLATZER PFO Occluder Post Approval Study
Abbott Medical Devices
NCT03309332
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
Johns Hopkins University
NCT06347484
Implementation of Neuro Lung Protective Ventilation
Colin Grissom
NCT03243539
Virtual Diabetes Group Visits Across Health Systems
University of Chicago
NCT06094491
Amulet™ ADVANCE LAA
Abbott Medical Devices
NCT05997446
BRINK (BRain In Kidney Disease) Memory Study 2.0
Anne Murray
NCT04975464
Video-based Intervention to Address Disparities in Blood Pressure Control After Stroke
The University of Texas Health Science Center, Houston
NCT05264298
Implementing Outcome Measures in Stroke Rehabilitation
Ohio State University
NCT04888416
Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion
Occlutech International AB
NCT05069558
Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)
University of Utah
NCT04845542
Brain-based Understanding of Individual Language Differences After Stroke
Georgetown University
NCT04991519
Telehealth Assessment and Skill-Building Intervention for Stroke Caregivers (TASK III)
University of Cincinnati
NCT05304078
Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy
University of California, San Francisco
NCT05361070
ProSPective Evaluation of Non-contrast sINe spiN Flat-dEtectoR CT for the Detection of Intracranial hemorrhageS
University Hospital, Basel, Switzerland
NCT05458908
Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients
Rush University Medical Center
NCT04337255
Stroke Prevention in Young Adults With Sickle Cell Anemia
Vanderbilt University Medical Center
NCT04808778
HD-tDCS for Phonological Impairment in Aphasia
Medical College of Wisconsin
NCT06010030
Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk
Shirley Ryan AbilityLab
NCT05076565
Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity
Dana-Farber Cancer Institute
NCT04717050
Epidemiology of Silent and Overt Strokes in Sickle Cell Disease
Vanderbilt University Medical Center
NCT03376893
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Stroke right now
218 recruiting of 456 indexed (48% open).
Phase mix: 16 late (III/IV) vs 69 early (I/II) (early-phase heavy).
Top sponsor: VA Office of Research and Development (27 trials), 9 others listed. 50 shown below, recruiting first. #9 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Stroke?
PlainTrial tracks 456 US clinical trials for Stroke, of which 218 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Stroke?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.