Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,707 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,707 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Enrollment posture brief
Registry condition stroke
OPEN 218 | RECR 48% | LATE 16 | EARLY 69 | RANK #9 | SPON 27
Volume-matched condition peers
Nearest open-share peer: Breast Cancer Stage II (48% recruiting · 23 trials)
Stroke lists 218 open slots (48% of 456 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
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Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
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Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 5 of 10
Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways
Peter C. Gerszten, MD
NCT07401186
Improving Stroke Motor Control With Non-invasive Brain Stimulation and Functional Electrical Stimulation
MetroHealth Medical Center
NCT03857529
Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment
University of Alabama at Birmingham
NCT05492513
CUped: An Approach to Motor Recovery Post-Stroke, Not Compensation
Marquette University
NCT06329765
Adaptive Hip Exoskeleton for Stroke Gait Enhancement
Georgia Institute of Technology
NCT05536739
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
Jorge Gonzalez-Martinez
NCT06303869
R3THA Rehabilitation Feasibility and Usability Study
Kessler Foundation
NCT06854978
EMG Controlled Device in Acute Rehabilitation After Acute Stroke
VA Office of Research and Development
NCT04599036
Evaluation of an Advanced Lower Extremity Neuroprostheses
Case Western Reserve University
NCT00623389
An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation
University of Pittsburgh
NCT04187131
Mobile Cognitive Behavioral Therapy for Stroke
Weill Medical College of Cornell University
NCT06689878
Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms
University of California, San Francisco
NCT02638701
Implant for Walking After Stroke
MetroHealth Medical Center
NCT05740540
VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration
Neuralink
NCT07224256
At-Home taVNS - Stroke Rehab
Medical University of South Carolina
NCT06616831
Passive Robots for Stroke Rehabilitation: A Feasibility Study
University of Michigan
NCT07218276
ECoG BMI for Motor and Speech Control
Karunesh Ganguly
NCT03698149
Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
Paradromics
NCT07357428
Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)
Anne Murray
NCT07224347
Genetic Testing of CYP2C19 in Prognostic Evaluation of Long-Term Major Adverse Cardiac and Vascular Events
University of Florida
NCT06855394
EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
Amgen
NCT05284747
ThRombectomy In Mild Ischemic Stroke With a Visible Intracranial veSsel Occlusion
University of Miami
NCT06778226
STROKE STAT (Stroke Severity-based Triage to Accelerate Treatment)
University of Alabama at Birmingham
NCT04978480
Sleep for Stroke Management and Recovery Trial
University of Michigan
NCT03812653
CHAMPION-AF Clinical Trial
Boston Scientific Corporation
NCT04394546
Amplatzer Amulet LAAO vs. NOAC
Abbott Medical Devices
NCT04226547
SIMPLAAFY Clinical Trial
Boston Scientific Corporation
NCT06521463
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis
University of Florida
NCT05047172
Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation
Anthos Therapeutics
NCT04755283
Genetic and Environmental Risk Factors for Hemorrhagic Stroke-GERFHS III
University of Cincinnati
NCT00930280
AMPLATZER PFO Occluder Post Approval Study
Abbott Medical Devices
NCT03309332
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
Johns Hopkins University
NCT06347484
Implementation of Neuro Lung Protective Ventilation
Colin Grissom
NCT03243539
Virtual Diabetes Group Visits Across Health Systems
University of Chicago
NCT06094491
Amulet™ ADVANCE LAA
Abbott Medical Devices
NCT05997446
BRINK (BRain In Kidney Disease) Memory Study 2.0
Anne Murray
NCT04975464
Video-based Intervention to Address Disparities in Blood Pressure Control After Stroke
The University of Texas Health Science Center, Houston
NCT05264298
Implementing Outcome Measures in Stroke Rehabilitation
Ohio State University
NCT04888416
Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion
Occlutech International AB
NCT05069558
Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)
University of Utah
NCT04845542
Brain-based Understanding of Individual Language Differences After Stroke
Georgetown University
NCT04991519
Telehealth Assessment and Skill-Building Intervention for Stroke Caregivers (TASK III)
University of Cincinnati
NCT05304078
Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy
University of California, San Francisco
NCT05361070
ProSPective Evaluation of Non-contrast sINe spiN Flat-dEtectoR CT for the Detection of Intracranial hemorrhageS
University Hospital, Basel, Switzerland
NCT05458908
Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients
Rush University Medical Center
NCT04337255
Stroke Prevention in Young Adults With Sickle Cell Anemia
Vanderbilt University Medical Center
NCT04808778
HD-tDCS for Phonological Impairment in Aphasia
Medical College of Wisconsin
NCT06010030
Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk
Shirley Ryan AbilityLab
NCT05076565
Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity
Dana-Farber Cancer Institute
NCT04717050
Epidemiology of Silent and Overt Strokes in Sickle Cell Disease
Vanderbilt University Medical Center
NCT03376893
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Named interventions
Most-linked intervention names on Stroke records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stroke trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stroke page
456 registered trials, 218 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 218 Stroke trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Stroke trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stroke condition card totals 456 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.