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NCT05458908 · ClinicalTrials.gov registry record · NA
ProSPective Evaluation of Non-contrast sINe spiN Flat-dEtectoR CT for the Detection of Intracranial hemorrhageS
A NA study of Stroke, sponsored by University Hospital, Basel, Switzerland.
- Active
- Registry status
- NA
- Development phase
- 252
- Enrollment target
- 14
- Study locations
NCT05458908: Active NA study of Stroke, sponsored by University Hospital, Basel, Switzerland.
NCT05458908 is a NA study of Stroke that is active but no longer recruiting, run by University Hospital, Basel, Switzerland. The registered enrollment target is 252 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (98% lower). The trial reports 14 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05458908, a NA study of Stroke, is active but no longer recruiting, sponsored by University Hospital, Basel, Switzerland.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 252 participants
- Enrollment target
- 14
- Study locations
Study Summary
Stroke is one of the leading causes of mortality and disability worldwide. Optimization of intra-hospital pathways is as of today one of the most promising research topics in stroke treatment. A potential solution to shorten the time needed for current workflows, and therefore reperfusion, is to do both imaging and subsequent endovascular therapy (EVT) in the angiography suite using non-contrast syngo DynaCT Sine Spin (FDCT) for the exclusion of intracranial hemorrhage and flat detector CT angiography (FDCTA) or digital subtraction angiography for diagnosis of LVO. It is still a matter of debate if FDCT can reliably differentiate between ischemic and hemorrhagic stroke. This study aims to investigate if non-contrast syngo DynaCT Sine Spin imaging is non-inferior to non-contrast MDCT imaging regarding its sensitivity and specificity for the detection of intracranial hemorrhages.
Primary Outcome
The primary outcome is the occurrence of intracranial hemorrhages (yes vs no) as assessed by a blinded core-lab. The primary outcome will be used to calculate the sensitivity and specificity of non-contrast syngo DynaCT Sine Spin imaging for the detection of intracranial hemorrhages. The primary outcome will be assessed on both scans.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Non-contrast cranial MDCT head scan
- DIAGNOSTIC_TEST Non-contrast syngo DynaCT Sine Spin head scan and application software
Study Locations (14)
Other
- HUS - Helsinki
- CHRU de Tours - Tours
- Hospital Vall d'Hebron - Barcelona
- University Hospital Basel - Basel
- Inselspital Bern - Bern
- Kantonsspital Luzern - Lucerne
Illinois
- AdvocateAurora Health - Chicago
- Nortshore University Health System - Chicago
New York
- New York University Langone Health - New York
- Mount Sinai Health System - New York
Colorado
- Swedish Medical Center - Denver
Pennsylvania
- Hospital of the University of Pennsylvania - Philadelphia
Tennessee
- Semmes Murphy Clinic - Memphis
Virginia
- University of Virginia Health System - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 252 participants |
| Start Date | 2022-10-25 |
| Est. Completion | 2026-03-15 |
| Phase | NA |
What the registry record for NCT05458908 still lists
NCT05458908 is an interventional study that assigns participants to a tested intervention. The registered 252 participants enrollment target is mid-sized for trials with a published cap, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which Non-contrast cranial MDCT head scan is the first listed.
NCT05458908 lists 14 locations in 7 states (Other, Illinois, New York).
Frequently Asked Questions
What is clinical trial NCT05458908 about?
NCT05458908 is a clinical study titled "ProSPective Evaluation of Non-contrast sINe spiN Flat-dEtectoR CT for the Detection of Intracranial hemorrhageS". Stroke is one of the leading causes of mortality and disability worldwide. Optimization of intra-hospital pathways is as of today one of the most promising research topics in stroke treatment. A potential solution to shorten the time needed for current workflows, and therefore reperfusion, is to do ...
What is the current status of trial NCT05458908?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 252 participants. The study started on 2022-10-25. Estimated completion is 2026-03-15.
What conditions does trial NCT05458908 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT05458908?
The interventions under investigation include: Non-contrast cranial MDCT head scan (DIAGNOSTIC_TEST), Non-contrast syngo DynaCT Sine Spin head scan and application software (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05458908?
This trial is sponsored by University Hospital, Basel, Switzerland, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05458908 being conducted?
This trial has 14 study locations across Colorado, Illinois, New York, Pennsylvania, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05458908's enrollment target sits among peer trials
252 85th of 454 higher than 370 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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