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NCT04991519 · ClinicalTrials.gov registry record
Brain-based Understanding of Individual Language Differences After Stroke
A clinical trial of Stroke and Aphasia, sponsored by Georgetown University.
- Active
- Registry status
- 400
- Enrollment target
- 1
- Study location
NCT04991519 is a study of Stroke and Aphasia that is active but no longer recruiting, run by Georgetown University. The registered enrollment target is 400 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04991519, a study of Stroke and Aphasia, is active but no longer recruiting, sponsored by Georgetown University.
- ACTIVE NOT RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
Strokes often cause a loss of communication ability, referred to as aphasia, as well as cognitive difficulties. Each stroke survivor has a unique pattern of strengths and weaknesses in communication and cognition, and a unique course of recovery. The BUILD study aims to understand the brain basis of these individual differences in stroke outcome. Participants with stroke as well as controls matched in age, educational background, race, and sex are examined using a combination of standardized and in-house tests of language and cognition to provide a detailed profile of strengths and weaknesses. Each participant will have between three and six sessions, including an MRI to measure details of the structure, function, and connections in the brain. The data are analyzed to test how patterns in the stroke lesion explain the patterns of communication and cognitive difficulties, and how patterns in the uninjured parts of the brain explain resilience and recovery from the stroke. Ultimately, we hope that BUILD will guide us toward new targets for brain stimulation treatments or other biologically based treatments that improve language and cognitive abilities after stroke.
Study Locations (1)
District of Columbia
- Georgetown University Medical Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2018-11-01 |
| Est. Completion | 2028-08-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04991519
The ClinicalTrials.gov registry entry for NCT04991519 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (97% lower). The listed sponsor is Georgetown University, which has 227 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 0 interventions.
NCT04991519 reports 1 study location spanning 1 distinct geographic area - top geographies include District of Columbia.
Frequently Asked Questions
What is clinical trial NCT04991519 about?
NCT04991519 is a clinical study titled "Brain-based Understanding of Individual Language Differences After Stroke". Strokes often cause a loss of communication ability, referred to as aphasia, as well as cognitive difficulties. Each stroke survivor has a unique pattern of strengths and weaknesses in communication and cognition, and a unique course of recovery. The BUILD study aims to understand the brain basis of...
What is the current status of trial NCT04991519?
This trial is currently active not recruiting. The enrollment target is 400 participants. The study started on 2018-11-01. Estimated completion is 2028-08-30.
What conditions does trial NCT04991519 study?
This clinical trial studies the following conditions: Stroke, Aphasia, Alexia.
Who is sponsoring clinical trial NCT04991519?
This trial is sponsored by Georgetown University, which has 227 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04991519 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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