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NCT04991519 · ClinicalTrials.gov registry record
Brain-based Understanding of Individual Language Differences After Stroke
A clinical trial of Stroke and Aphasia, sponsored by Georgetown University.
- Active
- Registry status
- 400
- Enrollment target
- 1
- Study location
NCT04991519: Active study of Stroke and Aphasia, sponsored by Georgetown University.
NCT04991519 is a study of Stroke and Aphasia that is active but no longer recruiting, run by Georgetown University. The registered enrollment target is 400 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04991519, a study of Stroke and Aphasia, is active but no longer recruiting, sponsored by Georgetown University.
- ACTIVE NOT RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
Strokes often cause a loss of communication ability, referred to as aphasia, as well as cognitive difficulties. Each stroke survivor has a unique pattern of strengths and weaknesses in communication and cognition, and a unique course of recovery. The BUILD study aims to understand the brain basis of these individual differences in stroke outcome. Participants with stroke as well as controls matched in age, educational background, race, and sex are examined using a combination of standardized and in-house tests of language and cognition to provide a detailed profile of strengths and weaknesses. Each participant will have between three and six sessions, including an MRI to measure details of the structure, function, and connections in the brain. The data are analyzed to test how patterns in the stroke lesion explain the patterns of communication and cognitive difficulties, and how patterns in the uninjured parts of the brain explain resilience and recovery from the stroke. Ultimately, we hope that BUILD will guide us toward new targets for brain stimulation treatments or other biologically based treatments that improve language and cognitive abilities after stroke.
Primary Outcome
Part of MRI sequence that measures deep grey matter structure.
Study Locations (1)
District of Columbia
- Georgetown University Medical Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2018-11-01 |
| Est. Completion | 2028-08-30 |
What the registry record for NCT04991519 still lists
NCT04991519 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (97% lower).
The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 0 interventions.
NCT04991519 reports a single indexed study location in District of Columbia.
Frequently Asked Questions
What is clinical trial NCT04991519 about?
NCT04991519 is a clinical study titled "Brain-based Understanding of Individual Language Differences After Stroke". Strokes often cause a loss of communication ability, referred to as aphasia, as well as cognitive difficulties. Each stroke survivor has a unique pattern of strengths and weaknesses in communication and cognition, and a unique course of recovery. The BUILD study aims to understand the brain basis of...
What is the current status of trial NCT04991519?
This trial is currently active not recruiting. The enrollment target is 400 participants. The study started on 2018-11-01. Estimated completion is 2028-08-30.
What conditions does trial NCT04991519 study?
This clinical trial studies the following conditions: Stroke, Aphasia, Alexia.
Who is sponsoring clinical trial NCT04991519?
This trial is sponsored by Georgetown University, which has 227 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04991519 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04991519's enrollment target sits among peer trials
400 65th of 454 higher than 388 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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