Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 218 recruiting now early-phase tilt #9 of 28,963 conditions

Stroke: early-phase trial registry

218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #9 of 28,963 conditions by registered trial count.

456 US clinical trials · 218 currently recruiting · #9 of 28,963 conditions by registered trial count

Stroke: 456 US clinical trials tracked, 218 recruiting.

Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.

Open enrollment, early-phase tilt

Stroke has 456 registered US clinical trials, 218 of them open to new participants right now, about 48% of the total.

218
recruiting participants now
48%
of trials open to enrollment
16
in Phase 3-4 (later-stage)
27
top sponsor: VA Office of Research and Development

Corpus placement: #9 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Stroke is recruiting above its size-band peers.

    218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Stroke trials is spread across many organizations.

    VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.

  3. Most Stroke trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.

  4. Stroke research is mostly interventional.

    385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 135Phase 234Phase 37Phase 49

Open and recent trials

456 total, page 6 of 10

ACTIVE NOT RECRUITING 100 participants

Muscle Atrophy, Physical Performance and Glucose Tolerance Post Stroke

Baltimore VA Medical Center

NCT01302197

ACTIVE NOT RECRUITING NA 100 participants

Muscle Coordination-Based Feedback for Stroke Rehabilitation

Shirley Ryan AbilityLab

NCT06099444

ACTIVE NOT RECRUITING NA 100 participants

MyStroke in Chronic Stroke

University of Pennsylvania

NCT06057753

ACTIVE NOT RECRUITING NA 93 participants

Resistive Training Combined With Nutritional Therapy After Stroke

VA Office of Research and Development

NCT02347995

ACTIVE NOT RECRUITING NA 91 participants

Perturbation Training for Fall-risk Reduction Among Stroke Survivors

University of Illinois at Chicago

NCT03205527

ACTIVE NOT RECRUITING NA 90 participants

teleABLE to Reduce Post-Stroke Sedentary Behavior

University of Minnesota

NCT06312709

ACTIVE NOT RECRUITING NA 82 participants

Transferring Speed of Processing Gains to Everyday Cognitive Tasks After Stroke

University of Alabama at Birmingham

NCT05162781

ACTIVE NOT RECRUITING NA 80 participants

Real-time Neuromuscular Control of Exoskeletons

Shirley Ryan AbilityLab

NCT04661891

ACTIVE NOT RECRUITING NA 80 participants

Augmenting a Post-Stroke Wellness Program With Respiratory Muscle Training

University of Florida

NCT05819333

ACTIVE NOT RECRUITING NA 65 participants

Group Lifestyle Balance™ for Individuals With Stroke (GLB-CVA)

Baylor Research Institute

NCT03873467

ACTIVE NOT RECRUITING 62 participants

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

University of Texas Southwestern Medical Center

NCT02791880

ACTIVE NOT RECRUITING NA 60 participants

Reflex Excitability in Post-stroke Stiff-Knee Gait

MetroHealth Medical Center

NCT04947865

ACTIVE NOT RECRUITING NA 60 participants

Home Based Tele-exercise for People With Chronic Neurological Impairments

Burke Medical Research Institute

NCT04564495

ACTIVE NOT RECRUITING 45 participants

A Biomarker for Personalized Care in Post-Stroke Spatial Neglect

VA Office of Research and Development

NCT05256563

ACTIVE NOT RECRUITING NA 45 participants

Perception of Electrical Stimuli in Individuals with Stroke

Netta Gurari

NCT05465005

ACTIVE NOT RECRUITING NA 40 participants

Effects of Vibration on Motor Function of Survivors of Chronic Stroke

Shirley Ryan AbilityLab

NCT06663501

ACTIVE NOT RECRUITING Phase 2 40 participants

Diffuse Optical Monitoring With Inhaled Nitric Oxide

Steven Messe

NCT03023449

ACTIVE NOT RECRUITING NA 40 participants

Impact of Group Participation on Adults With Aphasia

University of Arkansas

NCT05520528

ACTIVE NOT RECRUITING 40 participants

Validation of a Spasticity Measurement Tool

Shirley Ryan AbilityLab

NCT05374174

ACTIVE NOT RECRUITING 36 participants

Tracking Neural Synergies After Stroke.

Shirley Ryan AbilityLab

NCT04805866

ACTIVE NOT RECRUITING NA 32 participants

Dry Needling for Spasticity in Stroke

Medical University of South Carolina

NCT04535479

ACTIVE NOT RECRUITING Phase 1 30 participants

Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI

University of Texas Rio Grande Valley

NCT05589402

ACTIVE NOT RECRUITING NA 30 participants

Robot-Assisted Rehabilitation After HIV-Associated Stroke: Botswana

University of Pennsylvania

NCT04488250

ACTIVE NOT RECRUITING NA 20 participants

Assessing Upper Extremity Function in Chronic Stroke Survivors Through Acute Intermittent Hypoxia

Shirley Ryan AbilityLab

NCT07113457

ACTIVE NOT RECRUITING NA 20 participants

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

Thomas Jefferson University

NCT04798378

ACTIVE NOT RECRUITING NA 20 participants

Safety and Feasibility of ExoNET

Shirley Ryan AbilityLab

NCT05180812

ACTIVE NOT RECRUITING NA 11 participants

A New At-home Telerehabilitation Care Service Delivery Model for Stroke Survivors in the Rio Grande Valley

The University of Texas Health Science Center, Houston

NCT06580548

ACTIVE NOT RECRUITING NA 10 participants

Ankle Exosuit Training in the Clinic to Community Community

Arun Jayaraman, PT, PhD

NCT04251091

ACTIVE NOT RECRUITING NA 5 participants

Stimulation Combined With Powered Motorized Orthoses for Walking After Stroke

VA Office of Research and Development

NCT04116671

COMPLETED 1,234,412 participants

A Study to Assess Stroke Risk Among Users of Typical Versus Atypical Antipsychotics Stratified by Broad Age Group

Janssen Research & Development

NCT04002700

COMPLETED 37,235 participants

GLORIA-AF Registry Program - Second and Third Phases

Boehringer Ingelheim

NCT01468701

COMPLETED Phase 3 18,113 participants

Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) With Dabigatran Etexilate

Boehringer Ingelheim

NCT00262600

COMPLETED NA 10,800 participants

Testing a Community Intervention to Increase Aspirin Use

University of Minnesota

NCT02607917

COMPLETED NA 6,024 participants

Comprehensive Post-Acute Stroke Services

Wake Forest University Health Sciences

NCT02588664

COMPLETED 6,000 participants

Addressing Real-world Anticoagulant Management Issues in Stroke

Duke University

NCT02478177

COMPLETED NA 5,970 participants

Stroke Ready - Optimizing Acute Stroke Care

University of Michigan

NCT03645590

COMPLETED Phase 3 5,390 participants

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Boehringer Ingelheim

NCT02239120

COMPLETED NA 5,000 participants

Clinical Decision Support for Medication Management and Adherence

Duke University

NCT00979225

COMPLETED NA 4,614 participants

Effect of Intervention to Improve Stroke Recognition

Columbia University

NCT01497886

COMPLETED 2,005 participants

Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities

Georgetown University

NCT00724555

COMPLETED 1,877 participants

Patient-centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research

Duke University

NCT02146274

COMPLETED 1,244 participants

Levels of Inflammatory Markers in the Treatment of Stroke-An SPS3 Ancillary Study

Columbia University

NCT00579306

COMPLETED 840 participants

Genetic Studies to Identify Stroke Subtypes and Outcome

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00357513

COMPLETED NA 664 participants

GORE® Septal Occluder Device for Patent Foramen Ovale (PFO) Closure in Stroke Patients

W.L.Gore & Associates

NCT00738894

COMPLETED NA 641 participants

MINDSPACE Strategy for Risk Optimization

Indiana Institute for Medical Research

NCT02721446

COMPLETED NA 561 participants

LEAVE Safe With DOACs

University of Massachusetts, Worcester

NCT04068727

COMPLETED NA 495 participants

Center for Stroke Disparities Solution - Community Transitions Intervention

Visiting Nurse Service of New York

NCT01918891

COMPLETED Phase 3 408 participants

Locomotor Experience Applied Post Stroke Trial

Duke University

NCT00243919

COMPLETED Phase 4 355 participants

Improving Cardiovascular Risk Prediction Using Hand Held Carotid Ultrasonography Study

University of Wisconsin, Madison

NCT00574457

COMPLETED 350 participants

The Afolabi Stroke Registry for Children and Young Adults With SCD in Northern Nigeria

Vanderbilt University Medical Center

NCT04800809

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Phase Distribution

PhaseTrial count
Phase 1 35
Phase 2 34
Phase 3 7
Phase 4 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Stroke right now

218 recruiting of 456 indexed (48% open).

Phase mix: 16 late (III/IV) vs 69 early (I/II) (early-phase heavy).

Top sponsor: VA Office of Research and Development (27 trials), 9 others listed. 50 shown below, recruiting first. #9 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Stroke?

PlainTrial tracks 456 US clinical trials for Stroke, of which 218 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stroke?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.