Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,707 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,707 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Enrollment posture brief
Registry condition stroke
OPEN 218 | RECR 48% | LATE 16 | EARLY 69 | RANK #9 | SPON 27
Volume-matched condition peers
Nearest open-share peer: Breast Cancer Stage II (48% recruiting · 23 trials)
Stroke lists 218 open slots (48% of 456 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
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Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
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Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 6 of 10
Muscle Atrophy, Physical Performance and Glucose Tolerance Post Stroke
Baltimore VA Medical Center
NCT01302197
Muscle Coordination-Based Feedback for Stroke Rehabilitation
Shirley Ryan AbilityLab
NCT06099444
MyStroke in Chronic Stroke
University of Pennsylvania
NCT06057753
Resistive Training Combined With Nutritional Therapy After Stroke
VA Office of Research and Development
NCT02347995
Perturbation Training for Fall-risk Reduction Among Stroke Survivors
University of Illinois at Chicago
NCT03205527
teleABLE to Reduce Post-Stroke Sedentary Behavior
University of Minnesota
NCT06312709
Transferring Speed of Processing Gains to Everyday Cognitive Tasks After Stroke
University of Alabama at Birmingham
NCT05162781
Real-time Neuromuscular Control of Exoskeletons
Shirley Ryan AbilityLab
NCT04661891
Augmenting a Post-Stroke Wellness Program With Respiratory Muscle Training
University of Florida
NCT05819333
Group Lifestyle Balance™ for Individuals With Stroke (GLB-CVA)
Baylor Research Institute
NCT03873467
Acute Kidney Injury Genomics and Biomarkers in TAVR Study
University of Texas Southwestern Medical Center
NCT02791880
Reflex Excitability in Post-stroke Stiff-Knee Gait
MetroHealth Medical Center
NCT04947865
Home Based Tele-exercise for People With Chronic Neurological Impairments
Burke Medical Research Institute
NCT04564495
A Biomarker for Personalized Care in Post-Stroke Spatial Neglect
VA Office of Research and Development
NCT05256563
Perception of Electrical Stimuli in Individuals with Stroke
Netta Gurari
NCT05465005
Effects of Vibration on Motor Function of Survivors of Chronic Stroke
Shirley Ryan AbilityLab
NCT06663501
Diffuse Optical Monitoring With Inhaled Nitric Oxide
Steven Messe
NCT03023449
Impact of Group Participation on Adults With Aphasia
University of Arkansas
NCT05520528
Validation of a Spasticity Measurement Tool
Shirley Ryan AbilityLab
NCT05374174
Tracking Neural Synergies After Stroke.
Shirley Ryan AbilityLab
NCT04805866
Dry Needling for Spasticity in Stroke
Medical University of South Carolina
NCT04535479
Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI
University of Texas Rio Grande Valley
NCT05589402
Robot-Assisted Rehabilitation After HIV-Associated Stroke: Botswana
University of Pennsylvania
NCT04488250
Assessing Upper Extremity Function in Chronic Stroke Survivors Through Acute Intermittent Hypoxia
Shirley Ryan AbilityLab
NCT07113457
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
Thomas Jefferson University
NCT04798378
Safety and Feasibility of ExoNET
Shirley Ryan AbilityLab
NCT05180812
A New At-home Telerehabilitation Care Service Delivery Model for Stroke Survivors in the Rio Grande Valley
The University of Texas Health Science Center, Houston
NCT06580548
Ankle Exosuit Training in the Clinic to Community Community
Arun Jayaraman, PT, PhD
NCT04251091
Stimulation Combined With Powered Motorized Orthoses for Walking After Stroke
VA Office of Research and Development
NCT04116671
A Study to Assess Stroke Risk Among Users of Typical Versus Atypical Antipsychotics Stratified by Broad Age Group
Janssen Research & Development
NCT04002700
GLORIA-AF Registry Program - Second and Third Phases
Boehringer Ingelheim
NCT01468701
Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) With Dabigatran Etexilate
Boehringer Ingelheim
NCT00262600
Testing a Community Intervention to Increase Aspirin Use
University of Minnesota
NCT02607917
Comprehensive Post-Acute Stroke Services
Wake Forest University Health Sciences
NCT02588664
Addressing Real-world Anticoagulant Management Issues in Stroke
Duke University
NCT02478177
Stroke Ready - Optimizing Acute Stroke Care
University of Michigan
NCT03645590
Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)
Boehringer Ingelheim
NCT02239120
Clinical Decision Support for Medication Management and Adherence
Duke University
NCT00979225
Effect of Intervention to Improve Stroke Recognition
Columbia University
NCT01497886
Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities
Georgetown University
NCT00724555
Patient-centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research
Duke University
NCT02146274
Levels of Inflammatory Markers in the Treatment of Stroke-An SPS3 Ancillary Study
Columbia University
NCT00579306
Genetic Studies to Identify Stroke Subtypes and Outcome
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00357513
GORE® Septal Occluder Device for Patent Foramen Ovale (PFO) Closure in Stroke Patients
W.L.Gore & Associates
NCT00738894
MINDSPACE Strategy for Risk Optimization
Indiana Institute for Medical Research
NCT02721446
LEAVE Safe With DOACs
University of Massachusetts, Worcester
NCT04068727
Center for Stroke Disparities Solution - Community Transitions Intervention
Visiting Nurse Service of New York
NCT01918891
Locomotor Experience Applied Post Stroke Trial
Duke University
NCT00243919
Improving Cardiovascular Risk Prediction Using Hand Held Carotid Ultrasonography Study
University of Wisconsin, Madison
NCT00574457
The Afolabi Stroke Registry for Children and Young Adults With SCD in Northern Nigeria
Vanderbilt University Medical Center
NCT04800809
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Named interventions
Most-linked intervention names on Stroke records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stroke trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stroke page
456 registered trials, 218 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 218 Stroke trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Stroke trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stroke condition card totals 456 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.