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NCT03243539 · ClinicalTrials.gov registry record · NA

Implementation of Neuro Lung Protective Ventilation

A NA study of Stroke and Traumatic Brain Injury, sponsored by Colin Grissom.

Active
Registry status
NA
Development phase
728
Enrollment target
1
Study location

NCT03243539 is a NA study of Stroke and Traumatic Brain Injury that is active but no longer recruiting, run by Colin Grissom. The registered enrollment target is 728 participants, below the 12,015-participant average among 454 other Stroke trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03243539, a NA study of Stroke and Traumatic Brain Injury, is active but no longer recruiting, sponsored by Colin Grissom.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
728 participants
Enrollment target
1
Study location

Study Summary

Patients who experience lung injury are often placed on a ventilator to help them heal; however, if the ventilator volume settings are too high, it can cause additional lung injury. It is proven that using lower ventilator volume settings improves outcomes. In patients with acute brain injury, it is proven that maintaining a normal partial pressure of carbon dioxide in the arterial blood improves outcomes. Mechanical ventilator settings with higher volumes and higher breathing rates are sometimes required to maintain a normal partial pressure of carbon dioxide. These 2 goals of mechanical ventilation, using lower volumes to prevent additional lung injury but maintaining a normal partial pressure of carbon dioxide, are both important for patients with acute brain injury. The investigators have designed a computerized ventilator protocol in iCentra that matches the current standard of care for mechanical ventilation of patients with acute brain injury by targeting a normal partial pressure of carbon dioxide with the lowest ventilator volume required. This is a quality improvement study with the purpose of observing and measuring the effects of implementation of a standard of care mechanical ventilation protocol for patients with acute brain injury in the iCentra electronic medical record system at Intermountain Medical Center. We hypothesize that implementation of a standardized neuro lung protective ventilation protocol will be feasible, will achieve a target normal partial pressure of carbon dioxide, will decrease tidal volumes toward the target 6 mL/kg predicted body weight, and will improve outcomes.

Interventions

  • PROCEDURE Lung Protective Ventilation

Study Locations (1)

Utah

  • Intermountain Medical Center - Murray

Trial Details

FieldValue
Enrollment Target 728 participants
Start Date 2017-08-31
Est. Completion 2024-12-31
Phase NA

Sponsor

Colin Grissom

1 total trials

What the Registry Record Tells You About NCT03243539

The ClinicalTrials.gov registry entry for NCT03243539 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 728 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,015-participant average among 454 other Stroke trials with a reported enrollment target (94% lower). The listed sponsor is Colin Grissom, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which Lung Protective Ventilation is the first listed.

NCT03243539 reports 1 study location spanning 1 distinct geographic area - top geographies include Utah.

Frequently Asked Questions

What is clinical trial NCT03243539 about?

NCT03243539 is a clinical study titled "Implementation of Neuro Lung Protective Ventilation". Patients who experience lung injury are often placed on a ventilator to help them heal; however, if the ventilator volume settings are too high, it can cause additional lung injury. It is proven that using lower ventilator volume settings improves outcomes. In patients with acute brain injury, it is...

What is the current status of trial NCT03243539?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 728 participants. The study started on 2017-08-31. Estimated completion is 2024-12-31.

What conditions does trial NCT03243539 study?

This clinical trial studies the following conditions: Stroke, Traumatic Brain Injury, Intracerebral Hemorrhage, Acute Brain Injury, Cerebral Edema.

What interventions are being tested in trial NCT03243539?

The interventions under investigation include: Lung Protective Ventilation (PROCEDURE).

Who is sponsoring clinical trial NCT03243539?

This trial is sponsored by Colin Grissom, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03243539 being conducted?

This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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