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NCT07401186 · ClinicalTrials.gov registry record · NA
Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways
A NA study of Stroke and Able Bodied, sponsored by Peter C. Gerszten, MD.
- Recruiting
- Registry status
- NA
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT07401186: Recruiting NA study of Stroke and Able Bodied, sponsored by Peter C. Gerszten, MD.
NCT07401186 is a NA study of Stroke and Able Bodied that is actively recruiting participants, run by Peter C. Gerszten, MD. The registered enrollment target is 15 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07401186, a NA study of Stroke and Able Bodied, is actively recruiting participants, sponsored by Peter C. Gerszten, MD.
- RECRUITING
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to assess cervical (neck) reflexes by intra-operatively stimulating the neck nerve roots to evoke motor responses through their connections to spinal motoneurons. This data is critical to reveal changes to the spinal sensory modulating circuitry in neurological disorders like stroke.
Primary Outcome
The investigators will record intramuscular electromyogram (EMG) of the hand and arm muscles evoked by dorsal nerve root stimulation at various frequencies to quantify spinal circuit excitability through the H-reflex. A mean difference of 10% from the baseline (first pulse per frequency) muscle activation will be considered a meaningful change in excitability.
Conditions Studied
Interventions
- DEVICE Bipolar Neural Stimulation Electrode
Study Locations (1)
Pennsylvania
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2026-05 |
| Est. Completion | 2028-01 |
| Phase | NA |
What NCT07401186 shows while recruiting
NCT07401186 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which Bipolar Neural Stimulation Electrode is the first listed.
NCT07401186 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07401186 about?
NCT07401186 is a clinical study titled "Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways". The goal of this study is to assess cervical (neck) reflexes by intra-operatively stimulating the neck nerve roots to evoke motor responses through their connections to spinal motoneurons. This data is critical to reveal changes to the spinal sensory modulating circuitry in neurological disorders li...
What is the current status of trial NCT07401186?
This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2026-05. Estimated completion is 2028-01.
What conditions does trial NCT07401186 study?
This clinical trial studies the following conditions: Stroke, Able Bodied.
What interventions are being tested in trial NCT07401186?
The interventions under investigation include: Bipolar Neural Stimulation Electrode (DEVICE).
Who is sponsoring clinical trial NCT07401186?
This trial is sponsored by Peter C. Gerszten, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07401186 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07401186's enrollment target sits among peer trials
15 391st of 454 higher than 56 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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