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NCT05157282 · ClinicalTrials.gov registry record · NA

Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia

A NA study of Spinal Cord Injury, sponsored by VA Office of Research and Development.

Recruiting
Registry status
NA
Development phase
86
Enrollment target
2
Study locations

NCT05157282: Recruiting NA study of Spinal Cord Injury, sponsored by VA Office of Research and Development.

NCT05157282 is a NA study of Spinal Cord Injury that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 86 participants, roughly in line with the 85-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target. The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05157282, a NA study of Spinal Cord Injury, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
NA
Development phase
86 participants
Enrollment target
2
Study locations

Study Summary

In support of the long-term goal of developing new strategies to increase limb function after SCI, the objectives of this proposal are to: 1) Examine the behavioral and physiological effects of TESS on upper-limb muscles after cervical SCI; and 2) Maximize the recovery of reaching and grasping potential by using tailored TESS in a task-specific manner with motor training. Veterans with cervical spinal injuries and healthy volunteers will be recruited for this study.

Primary Outcome

Ten stimuli (0.2 Hz) will be delivered at each intensity to plot the mean peak-to-peak amplitude of the MEP from the non-rectified response against the TMS intensity in each subject (MEP recruitment curve).

Conditions Studied

Interventions

  • DEVICE TESS
  • OTHER Training
  • OTHER Motor Task
  • DEVICE sham-TESS

Study Locations (2)

Illinois

  • Shirley Ryan AbilityLab - Chicago
  • Edward Hines Jr. VA Hospital, Hines, IL - Hines

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2023-01-25
Est. Completion 2027-02-01
Phase NA
VA Office of Research and Development

1,668 total trials

What NCT05157282 shows while recruiting

NCT05157282 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, roughly in line with the 85-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target.

The record links to 1 condition, with Spinal Cord Injury appearing as the primary indexed condition, and to 4 interventions - of which TESS is the first listed.

NCT05157282 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT05157282 about?

NCT05157282 is a clinical study titled "Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia". In support of the long-term goal of developing new strategies to increase limb function after SCI, the objectives of this proposal are to: 1) Examine the behavioral and physiological effects of TESS on upper-limb muscles after cervical SCI; and 2) Maximize the recovery of reaching and grasping poten...

What is the current status of trial NCT05157282?

This trial is currently recruiting. It is a NA study. The enrollment target is 86 participants. The study started on 2023-01-25. Estimated completion is 2027-02-01.

What conditions does trial NCT05157282 study?

This clinical trial studies the following conditions: Spinal Cord Injury.

What interventions are being tested in trial NCT05157282?

The interventions under investigation include: TESS (DEVICE), Training (OTHER), Motor Task (OTHER), sham-TESS (DEVICE).

Who is sponsoring clinical trial NCT05157282?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05157282 being conducted?

This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Spinal Cord Injury

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05157282's enrollment target sits among peer trials

86 24th of 99 higher than 76 of 99 other Spinal Cord Injury trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Spinal Cord Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05157282, the US trial registry maintained by the National Library of Medicine. NCT05157282 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.