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NCT06841770 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
A Phase 1 study of Spinal Cord Injury and Spinal Cord Injury Cervical, sponsored by Lineage Cell Therapeutics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
- 2
- Study locations
NCT06841770: Recruiting Phase 1 study of Spinal Cord Injury and Spinal Cord Injury Cervical, sponsored by Lineage Cell Therapeutics.
NCT06841770 is a Phase 1 study of Spinal Cord Injury and Spinal Cord Injury Cervical that is actively recruiting participants, run by Lineage Cell Therapeutics. The registered enrollment target is 10 participants, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (88% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06841770, a Phase 1 study of Spinal Cord Injury and Spinal Cord Injury Cervical, is actively recruiting participants, sponsored by Lineage Cell Therapeutics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
- 2
- Study locations
Study Summary
The DOSED clinical study evaluates the safety and utility of a novel delivery device to deliver LCTOPC1, a cell therapy, to the spinal cord of patients with a spinal cord injury (SCI). LCTOPC1 is designed to replace or support cells that are absent or dysfunctional due to traumatic injury, with a goal to help improve the quality of life and restore or augment functional activity in persons suffering from a traumatic cervical or thoracic injuries.
Primary Outcome
Frequency and severity of the MI PSD System or injection procedure related adverse events (AEs) through 30 days (1 month).
Conditions Studied
Interventions
- BIOLOGICAL OPC1
Study Locations (2)
California
- Rancho Research Institue - Downey
- University of California, San Diego - La Jolla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-06-30 |
| Est. Completion | 2037-06-30 |
| Phase | Phase 1 |
What NCT06841770 shows while recruiting
NCT06841770 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (88% lower).
The record links to 5 conditions, with Spinal Cord Injury appearing as the primary indexed condition, and to 1 intervention - of which OPC1 is the first listed.
NCT06841770 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06841770 about?
NCT06841770 is a clinical study titled "A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury". The DOSED clinical study evaluates the safety and utility of a novel delivery device to deliver LCTOPC1, a cell therapy, to the spinal cord of patients with a spinal cord injury (SCI). LCTOPC1 is designed to replace or support cells that are absent or dysfunctional due to traumatic injury, with a go...
What is the current status of trial NCT06841770?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2025-06-30. Estimated completion is 2037-06-30.
What conditions does trial NCT06841770 study?
This clinical trial studies the following conditions: Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Spinal Cord Injury, Chronic, Spinal Cord Injury, Acute.
What interventions are being tested in trial NCT06841770?
The interventions under investigation include: OPC1 (BIOLOGICAL).
Who is sponsoring clinical trial NCT06841770?
This trial is sponsored by Lineage Cell Therapeutics, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06841770 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06841770's enrollment target sits among peer trials
10 82nd of 99 higher than 8 of 99 other Spinal Cord Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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