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NCT07179822 · ClinicalTrials.gov registry record · NA
Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)
A NA study of Spinal Cord Injury and Spinal Cord Injuries and Disorders (SCI/D), sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- NA
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT07179822: Recruiting NA study of Spinal Cord Injury and Spinal Cord Injuries and Disorders (SCI/D), sponsored by Medical University of South Carolina.
NCT07179822 is a NA study of Spinal Cord Injury and Spinal Cord Injuries and Disorders (SCI/D) that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 15 participants, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07179822, a NA study of Spinal Cord Injury and Spinal Cord Injuries and Disorders (SCI/D), is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to examine the effect of a brain stimulation training to improve the function of brain-spinal cord- muscle connections. Because brain-to-muscle pathways are very important in our movement control, restoring function of these pathways may improve movement problems after injuries. Spinal cord injury causes damage to the brain-to-muscle connection. However, when the injury is "incomplete", there is a possibility that some of the brain-to-muscle pathways are still connected and may be trained to improve movement function. For examining brain-to-muscle pathways, investigators use a transcranial magnetic stimulator. Investigators hope that the results of this research study will help us develop new treatments for people who have movement disabilities. This study will require about 42 visits over the first 14 weeks, and another 6 visits over an additional 3 months. Each visit will take about 1 ½ hours.
Primary Outcome
MEP from each session is expressed as the percent of the initial MEP size (average MEP size from the 6 baseline sessions). The final MEP size is the fitted estimate of the MEP size at the end of 24 intervention sessions. MEP size is a measurement of the integrity of the corticospinal tract.
Conditions Studied
Interventions
- BEHAVIORAL Motor Evoked Potential (MEP) Operant Conditioning
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2025-11-03 |
| Est. Completion | 2027-09-30 |
| Phase | NA |
What NCT07179822 shows while recruiting
NCT07179822 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (83% lower).
The record links to 2 conditions, with Spinal Cord Injury appearing as the primary indexed condition, and to 1 intervention - of which Motor Evoked Potential (MEP) Operant Conditioning is the first listed.
NCT07179822 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT07179822 about?
NCT07179822 is a clinical study titled "Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)". The purpose of this research study is to examine the effect of a brain stimulation training to improve the function of brain-spinal cord- muscle connections. Because brain-to-muscle pathways are very important in our movement control, restoring function of these pathways may improve movement problem...
What is the current status of trial NCT07179822?
This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2025-11-03. Estimated completion is 2027-09-30.
What conditions does trial NCT07179822 study?
This clinical trial studies the following conditions: Spinal Cord Injury, Spinal Cord Injuries and Disorders (SCI/D).
What interventions are being tested in trial NCT07179822?
The interventions under investigation include: Motor Evoked Potential (MEP) Operant Conditioning (BEHAVIORAL).
Who is sponsoring clinical trial NCT07179822?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07179822 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07179822's enrollment target sits among peer trials
15 68th of 99 higher than 28 of 99 other Spinal Cord Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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