Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 38 recruiting now early-phase tilt #136 of 28,707 conditions

Spinal Cord Injury: early-phase trial registry

38 of 100 indexed Spinal Cord Injury trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #136 of 28,707 conditions by registered trial count.

100 US clinical trials · 38 currently recruiting · #136 of 28,707 conditions by registered trial count

Spinal Cord Injury: 100 US clinical trials tracked, 38 recruiting.

Spinal Cord Injury is the subject of 100 registered US clinical trials on ClinicalTrials.gov, 38 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 15 of these trials.

Enrollment posture brief

Registry condition spinal-cord-injury

OPEN 38 | RECR 38% | LATE 5 | EARLY 26 | RANK #136 | SPON 15

Nearest open-share peer: Behavior, Health (38% recruiting · 21 trials)

Pregnancy Related56%Prostate Adenocarcinoma45%Systemic Lupus Erythematosus43%Spinal Cord Injury (this)38%Colon Cancer34.3%
Open-enrollment share among volume-matched conditions near Spinal Cord Injury

Spinal Cord Injury lists 38 open slots (38% of 100 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Spinal Cord Injury on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Spinal Cord Injury recruits in line with its size-band peers.

    38 of 100 indexed trials (38%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Spinal Cord Injury research.

    VA Office of Research and Development accounts for 15 of 100 trials (15%). 58 distinct sponsors appear on at least one study for this condition label.

  3. Most Spinal Cord Injury trials plan to enrol fewer than 100 people.

    Median target enrolment is 25 among the 100 trials that report a genuine target (sentinel values excluded). 82 of those (82%) plan for fewer than 100 participants.

  4. Spinal Cord Injury research is mostly interventional.

    81 interventional and 19 observational studies make up this index (81% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 19Phase 217Phase 32Phase 43

Open and recent trials

100 total, page 2 of 2

COMPLETED 170 participants

Cardiovascular Disease Study

VA Office of Research and Development

NCT00857194

COMPLETED NA 148 participants

Maintenance of Shoulder Health and Function After Spinal Cord Injury

Rancho Research Institute

NCT02135978

COMPLETED 146 participants

Baseline Cardiovascular Measurements in Pediatric Spinal Cord Injury

Shriners Hospitals for Children

NCT01599455

COMPLETED Phase 3 120 participants

Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.

Elan Pharmaceuticals

NCT00047580

COMPLETED NA 94 participants

Randomized Trial of Early Hemodynamic Management of Patients Following Acute Spinal Cord Injury

Oregon Health and Science University

NCT02878850

COMPLETED 94 participants

MR Spectroscopy as a Diagnostic and Outcome Measure in Pain and SCI

US Department of Veterans Affairs

NCT00561782

COMPLETED 93 participants

Neurofeedback Treatment of Pain in Persons With Spinal Cord Injury (SCI)

University of Washington

NCT00947999

COMPLETED 92 participants

A Longitudinal Examination of Aging With a Spinal Cord Injury: Cardiovascular, Cerebrovascular and Cognitive Consequences

James J. Peters Veterans Affairs Medical Center

NCT03023163

COMPLETED NA 81 participants

Re-Inventing Yourself After Spinal Cord Injury

Craig Hospital

NCT01633164

COMPLETED NA 73 participants

Treatment of Sleep-disordered Breathing in Patients With SCI

VA Office of Research and Development

NCT02830074

COMPLETED Phase 2 72 participants

Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

Tanabe Pharma America

NCT04683848

COMPLETED NA 67 participants

Virtual Walking for Neuropathic Pain in Spinal Cord Injury

University of Alabama at Birmingham

NCT01884662

COMPLETED 62 participants

Wheelchair Mobility Assessment of Individuals With Spinal Cord Injury

University of Miami

NCT01204047

COMPLETED Phase 2 60 participants

Prevention of Bone Loss After Acute SCI by Zoledronic Acid

Northwestern University

NCT02325414

COMPLETED NA 48 participants

Improving Hand and Arm Function After Spinal Cord Injury (SCI)

University of Miami

NCT01143597

COMPLETED Phase 1 48 participants

A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries

Vertex Pharmaceuticals Incorporated

NCT00500812

COMPLETED Phase 2 40 participants

Use of an Oral Beta-2 Agonist in Persons With Spinal Cord Injury

US Department of Veterans Affairs

NCT00755079

COMPLETED NA 38 participants

Comparison of Two Psycho-educational Family Group Interventions for Persons With SCI and Their Caregivers

St. Luke's Rehabilitation Institute

NCT02161913

COMPLETED NA 37 participants

Enhancing Self-Efficacy for Caregivers of Family Members With Spinal Cord Injury

Craig Hospital

NCT02392052

COMPLETED NA 34 participants

Treatment of Mild to Moderate Depression Symptoms in Patients With Spinal Cord Injury

University of Michigan

NCT00735670

COMPLETED Phase 2 34 participants

Safety and Efficacy of L-NAME and Midodrine to Increase MAP

US Department of Veterans Affairs

NCT00835224

COMPLETED 31 participants

Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia

Craig Hospital

NCT01815554

COMPLETED Phase 2 26 participants

Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical Trial

Brigham and Women's Hospital

NCT02218203

COMPLETED Phase 2 25 participants

12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)

Northwestern University

NCT02025179

COMPLETED Phase 2 23 participants

Fenofibrate Treatment in SCI

VA Office of Research and Development

NCT02455336

COMPLETED 20 participants

Experimental Evaluation of Wheelchair-Mounted Robotic Arms

University of South Florida

NCT01652352

COMPLETED NA 20 participants

Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation

The Cleveland Clinic

NCT01539109

COMPLETED Phase 4 19 participants

Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.

Craig Hospital

NCT00320281

COMPLETED NA 19 participants

Development and Feasibility of an Internet Intervention for Adults With Spinal Cord Injury to Prevent Pressure Ulcers

University of Virginia

NCT01885962

COMPLETED NA 19 participants

Development of Low Cost Devices to Increase Access to Treadmill Training

Shirley Ryan AbilityLab

NCT02560506

COMPLETED Phase 2 18 participants

Electrical Control of Bladder in Spinal Cord Injury Patients

US Department of Veterans Affairs

NCT00011570

COMPLETED NA 18 participants

Virtual Sailing Simulator in Individuals With Spinal Cord Injury

Hugo W. Moser Research Institute at Kennedy Krieger

NCT01491789

COMPLETED NA 18 participants

Effects of Salsalate on Prandial-Induced Vascular Inflammation After Spinal Cord Injury (SCI)

University of Miami

NCT01201759

COMPLETED NA 15 participants

Acute Effect of Ventilatory Support During Exercise in Spinal Cord Injury

Spaulding Rehabilitation Hospital

NCT03267212

COMPLETED 15 participants

Veteran-Centered Outcomes Using Qualitative and Quantitative Methods

US Department of Veterans Affairs

NCT00333580

COMPLETED Phase 2 12 participants

Testosterone and Long Pulse Stimulation After SCI

VA Office of Research and Development

NCT03345576

COMPLETED Phase 2 12 participants

Effects of Acute SCI on Colonic Motility & Tone

US Department of Veterans Affairs

NCT00013312

COMPLETED Phase 4 12 participants

Effect of Parathyroid Hormone (PTH) and Weight-Bearing on Bone in Spinal Cord Injury (SCI)

Thomas J. Schnitzer

NCT00826228

COMPLETED NA 11 participants

Ventilatory Support to Improve Exercise Training in High Level Spinal Cord Injury

Spaulding Rehabilitation Hospital

NCT02865343

COMPLETED NA 10 participants

Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury

VA Office of Research and Development

NCT04971408

COMPLETED NA 10 participants

Treating Cognitive Deficits in Spinal Cord Injury

James J. Peters Veterans Affairs Medical Center

NCT03037879

COMPLETED Phase 2 10 participants

24hr Effects of Tiotropium Bromide in Tetraplegia

James J. Peters Veterans Affairs Medical Center

NCT02586649

COMPLETED NA 10 participants

Identify Training Strategies for Progressing Exoskeleton Users Towards Everyday Functional Ambulation

Shirley Ryan AbilityLab

NCT02104622

COMPLETED NA 7 participants

Restoring Arm and Hand Function With Non-invasive Spinal Stimulation

NeuroEnabling Technologies

NCT01906424

COMPLETED Phase 2 6 participants

Effects of Electrical Stimulation and Vitamin D Supplementation on Bone Health Following Spinal Cord Injury.

VA Office of Research and Development

NCT05008484

COMPLETED Phase 1 6 participants

Platelet-Rich Plasma Therapy for Shoulder Pain in Persons With Spinal Cord Injury

Kessler Foundation

NCT01355549

COMPLETED NA 5 participants

Recovery of Cardiovascular Function With Epidural Stimulation After Human Spinal Cord Injury

University of Louisville

NCT02037620

COMPLETED 5 participants

Home/Work, Community Mobility Skills in the ReWalk Exoskeleton in Persons With SCI

James J. Peters Veterans Affairs Medical Center

NCT02118194

COMPLETED Phase 2 4 participants

Neuromodulation Techniques After SCI

VA Office of Research and Development

NCT04241250

COMPLETED NA 1 participants

Mechanisms of Arterial Hypotension in Chronic Spinal Cord Injury

University of Louisville

NCT02154412

← Previous Page 2 of 2

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 2 17
Phase 3 2
Phase 4 3

Named interventions

Most-linked intervention names on Spinal Cord Injury records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
4 trials
Sham Non-invasive ventilation(NIV) Device
2 trials
Placebo Other
2 trials
body weight-supported treadmill training Procedure
1 trials
tizanidine hydrochloride capsule Drug
1 trials
Placebo twice a day for 30 days. Then Salsalate 2gr BID for 30 days. Drug
1 trials
Salsalate 2grams twice a day for 30 days. Then Placebo for 30 days Drug
1 trials
Elastic assisted treadmill walking Device
1 trials

US sites by state

Facility locations filed on Spinal Cord Injury trials. A trial with sites in several states counts in each.

Illinois 15 trials
New York 14 trials
Florida 14 trials
Ohio 13 trials
California 12 trials
Pennsylvania 8 trials
Virginia 7 trials
Texas 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Spinal Cord Injury page

100 registered trials, 38 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Spinal Cord Injury condition card totals 100 registered trials; most-linked intervention Placebo; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.