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Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas
NCT03311412 · View on ClinicalTrials.gov ↗
Study Summary
The primary purpose of this study is to see if Sym021 is safe and tolerable as monotherapy, in combination with either Sym022 or Sym023, and in Combination with both Sym022 and Sym023 for patients with locally advanced/unresectable or metastatic solid tumor malignancies or lymphomas that are refractory to available therapy or for which no standard therapy is available.
Conditions Studied
Interventions
- DRUG Sym023
- DRUG Sym021
- DRUG Sym022
Study Locations (4)
Texas
- The University of Texas MD Anderson Cancer Center — Houston
- NEXT Oncology — San Antonio
Michigan
- South Texas Accelerated Research Therapeutics (START) Midwest — Grand Rapids
Ontario
- Princess Margaret Cancer Centre — Toronto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 89 participants |
| Start Date | 2017-11-20 |
| Est. Completion | 2022-03-23 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03311412
The ClinicalTrials.gov registry entry for NCT03311412 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 89 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Symphogen A/S, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Lymphoma appearing as the primary indexed condition, and to 3 interventions — of which Sym023 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03311412 reports 4 study locations spanning 3 distinct geographic areas — top geographies include Texas, Michigan, Ontario. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03311412 about?
NCT03311412 is a clinical study titled "Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas". The primary purpose of this study is to see if Sym021 is safe and tolerable as monotherapy, in combination with either Sym022 or Sym023, and in Combination with both Sym022 and Sym023 for patients with locally advanced/unresectable or metastatic solid tumor malignancies or lymphomas that are refract...
What is the current status of trial NCT03311412?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 89 participants. The study started on 2017-11-20. Estimated completion is 2022-03-23.
What conditions does trial NCT03311412 study?
This clinical trial studies the following conditions: Lymphoma, Solid Tumor, Metastatic Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03311412?
The interventions under investigation include: Sym023 (DRUG), Sym021 (DRUG), Sym022 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03311412?
This trial is sponsored by Symphogen A/S, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03311412 being conducted?
This trial has 4 study locations across Michigan, Texas, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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