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Sleep clinical trials
73 of 152 indexed Sleep trials are currently recruiting.
152 US clinical trials · 73 currently recruiting
Sleep is the subject of 152 registered US clinical trials on ClinicalTrials.gov, 73 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Pittsburgh, running 10 of these trials.
The research picture
Sleep has 152 registered US clinical trials, 73 of them open to new participants right now, about 48% of the total.
- 73
- recruiting participants now
- 48%
- of trials open to enrollment
- 7
- in Phase 3–4 (later-stage)
- 10
- top sponsor: University of Pittsburgh
Active & Recent Trials
152 total, page 2 of 4
A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers
University of Kansas Medical Center
NCT06667661
Bedtime Stories: Tailored Sleep Health Messaging for Caregivers
Boston Children's Hospital
NCT06618040
The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies
Nathaniel Jenkins
NCT06454344
Effect of Sleep Extension on Ceramides in People with Overweight and Obesity
University of Utah
NCT06180837
Sleep and Physical Activity in Patient and Caregiver Dyads Following Allogeneic Hematopoietic Cell Transplantation
M.D. Anderson Cancer Center
NCT07140770
Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty
University of Miami
NCT06902285
Student Exercise and Sleep Timing Study - Part 2
Rutgers, The State University of New Jersey
NCT06336590
Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators
Beth Israel Deaconess Medical Center
NCT05026541
Home Sleep Therapy for Older Adults With MCI
Brain Electrophysiology Laboratory Company
NCT05771844
The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors
Arizona State University
NCT06938555
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Rhode Island Hospital
NCT06737055
Sleepless at Scripps: An Inpatient White Noise Study
Scripps Health
NCT05475262
Optimizing Attention and Sleep Intervention Study
University of Pittsburgh
NCT05683756
Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities
Brigham and Women's Hospital
NCT06989619
Sleep and Circadian Mechanisms in Hypertension
Oregon Health and Science University
NCT05184933
Repurposing Low-Dose Clonidine for PTSD in Veterans
Wake Forest University Health Sciences
NCT04877093
The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
Massachusetts General Hospital
NCT04737200
Aerobic Exercise: A Potential Rescue From the Negative Ramifications of Poor Sleep
Florida State University
NCT06956963
Lemborexant Treatment of Insomnia Linked to Epilepsy
University of Manitoba
NCT06262594
Sleep Duration and Cardiovascular Health
Oregon Health and Science University
NCT04804124
Impact of Exogenous Ketones on Sleep and Breathing in Healthy Volunteers (K-SLEEP)
Johns Hopkins University
NCT07224074
Light Exposure, Migraine Outcomes, and Sleep Quality
Arizona State University
NCT07476053
Circadian Intervention to Improve Cardiometabolic Health
University of Utah
NCT05943626
Intern Health Study 2024
University of Michigan
NCT06465680
Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy
The Miriam Hospital
NCT02917876
Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)
The Miriam Hospital
NCT02412696
Evaluation of SLEEP Program
Michigan State University
NCT04727619
Evaluation of a Neurostimulation Device for Insomnia: A Randomized Trial
ProofPilot
NCT04627480
Diet, Food, Exercise and Nutrition During Social Distancing
University of Arkansas, Fayetteville
NCT04754074
SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty
Scripps Health
NCT04247646
Rested & Ready to Learn
University of South Carolina
NCT06882005
Impact of Sleep Extension in Adolescents
University of Colorado, Denver
NCT03500458
Sleep and Inflammatory Resolution Pathway
Beth Israel Deaconess Medical Center
NCT03377543
Sleep and Vascular Health Study
Auburn University
NCT05918744
Improving Sleep, Decision-Making, and Eating in Adolescents with Obesity
Drexel University
NCT06745570
Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study
University of Kansas Medical Center
NCT07008924
Sleep Improvement Via Environmental Smart Temperature Adjustments
Hebrew SeniorLife
NCT06770400
Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine
Washington University School of Medicine
NCT04206059
Intern Health Study 2022 and 2023
University of Michigan
NCT05436145
Apnea Positive Pressure Long-Term Efficacy Study
Stanford University
NCT00051363
Investigation of Sleep in the Intensive Care Unit
Massachusetts General Hospital
NCT03355053
VISC-Q Trial (Validation of an Online Sleep Characterization Questionnaire)
Philips Respironics
NCT03590795
Impact of Sleep Workshops in College Students
NYU Langone Health
NCT02665247
A Study to Assess the Effects of Dietary Supplement Drinks on Sleep, Stress and Mood
The Water Street Collective
NCT06378567
Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors-Renewal
Temple University
NCT03186508
Hangover, Congeners, Sleep and Occupational Performance
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00247585
Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness
Stanford University
NCT06001697
A Personalized Behavioral Intervention to Improve Physical Activity, Sleep and Cognition in Sedentary Older Adults
Johns Hopkins University
NCT03959202
A Study to Evaluate the Effect of SlimBiotics Probiotic Formula on Weight Management and Metabolic Health Outcomes
Slimbiotics
NCT05917314
Examining the Biological Factors That Affect Sleep Duration
Brigham and Women's Hospital
NCT00607204
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 8 |
| Phase 3 | 3 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Sleep Trial Landscape
152 indexed Sleep studies · 73 recruiting (48%).
Phase mix: 7 late (III/IV) vs 15 early (I/II).
Top sponsor: University of Pittsburgh (10 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Sleep?
PlainTrial tracks 152 US clinical trials for Sleep, of which 73 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Sleep?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.