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ClinicalTrials.gov 73 recruiting now official registry

Sleep clinical trials

73 of 152 indexed Sleep trials are currently recruiting.

152 US clinical trials · 73 currently recruiting

Sleep is the subject of 152 registered US clinical trials on ClinicalTrials.gov, 73 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Pittsburgh, running 10 of these trials.

The research picture

Sleep has 152 registered US clinical trials, 73 of them open to new participants right now, about 48% of the total.

73
recruiting participants now
48%
of trials open to enrollment
7
in Phase 3–4 (later-stage)
10
top sponsor: University of Pittsburgh
Phase 17Phase 28Phase 33Phase 44

Active & Recent Trials

152 total, page 2 of 4

RECRUITING NA 80 participants

A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers

University of Kansas Medical Center

NCT06667661

RECRUITING NA 75 participants

Bedtime Stories: Tailored Sleep Health Messaging for Caregivers

Boston Children's Hospital

NCT06618040

RECRUITING NA 70 participants

The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

Nathaniel Jenkins

NCT06454344

RECRUITING NA 70 participants

Effect of Sleep Extension on Ceramides in People with Overweight and Obesity

University of Utah

NCT06180837

RECRUITING 66 participants

Sleep and Physical Activity in Patient and Caregiver Dyads Following Allogeneic Hematopoietic Cell Transplantation

M.D. Anderson Cancer Center

NCT07140770

RECRUITING Phase 4 64 participants

Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty

University of Miami

NCT06902285

RECRUITING NA 62 participants

Student Exercise and Sleep Timing Study - Part 2

Rutgers, The State University of New Jersey

NCT06336590

RECRUITING NA 60 participants

Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators

Beth Israel Deaconess Medical Center

NCT05026541

RECRUITING NA 60 participants

Home Sleep Therapy for Older Adults With MCI

Brain Electrophysiology Laboratory Company

NCT05771844

RECRUITING NA 60 participants

The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors

Arizona State University

NCT06938555

RECRUITING NA 55 participants

The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers

Rhode Island Hospital

NCT06737055

RECRUITING NA 50 participants

Sleepless at Scripps: An Inpatient White Noise Study

Scripps Health

NCT05475262

RECRUITING NA 50 participants

Optimizing Attention and Sleep Intervention Study

University of Pittsburgh

NCT05683756

RECRUITING NA 45 participants

Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities

Brigham and Women's Hospital

NCT06989619

RECRUITING NA 32 participants

Sleep and Circadian Mechanisms in Hypertension

Oregon Health and Science University

NCT05184933

RECRUITING Phase 3 32 participants

Repurposing Low-Dose Clonidine for PTSD in Veterans

Wake Forest University Health Sciences

NCT04877093

RECRUITING NA 30 participants

The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU

Massachusetts General Hospital

NCT04737200

RECRUITING NA 30 participants

Aerobic Exercise: A Potential Rescue From the Negative Ramifications of Poor Sleep

Florida State University

NCT06956963

RECRUITING Phase 3 26 participants

Lemborexant Treatment of Insomnia Linked to Epilepsy

University of Manitoba

NCT06262594

RECRUITING NA 24 participants

Sleep Duration and Cardiovascular Health

Oregon Health and Science University

NCT04804124

RECRUITING Phase 1 20 participants

Impact of Exogenous Ketones on Sleep and Breathing in Healthy Volunteers (K-SLEEP)

Johns Hopkins University

NCT07224074

RECRUITING NA 20 participants

Light Exposure, Migraine Outcomes, and Sleep Quality

Arizona State University

NCT07476053

RECRUITING NA 20 participants

Circadian Intervention to Improve Cardiometabolic Health

University of Utah

NCT05943626

ACTIVE NOT RECRUITING NA 1,000 participants

Intern Health Study 2024

University of Michigan

NCT06465680

ACTIVE NOT RECRUITING 450 participants

Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy

The Miriam Hospital

NCT02917876

ACTIVE NOT RECRUITING NA 262 participants

Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)

The Miriam Hospital

NCT02412696

ACTIVE NOT RECRUITING NA 210 participants

Evaluation of SLEEP Program

Michigan State University

NCT04727619

ACTIVE NOT RECRUITING Phase 4 200 participants

Evaluation of a Neurostimulation Device for Insomnia: A Randomized Trial

ProofPilot

NCT04627480

ACTIVE NOT RECRUITING NA 150 participants

Diet, Food, Exercise and Nutrition During Social Distancing

University of Arkansas, Fayetteville

NCT04754074

ACTIVE NOT RECRUITING NA 120 participants

SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty

Scripps Health

NCT04247646

ACTIVE NOT RECRUITING NA 80 participants

Rested & Ready to Learn

University of South Carolina

NCT06882005

ACTIVE NOT RECRUITING NA 75 participants

Impact of Sleep Extension in Adolescents

University of Colorado, Denver

NCT03500458

ACTIVE NOT RECRUITING Early Phase 1 66 participants

Sleep and Inflammatory Resolution Pathway

Beth Israel Deaconess Medical Center

NCT03377543

ACTIVE NOT RECRUITING NA 60 participants

Sleep and Vascular Health Study

Auburn University

NCT05918744

ACTIVE NOT RECRUITING NA 50 participants

Improving Sleep, Decision-Making, and Eating in Adolescents with Obesity

Drexel University

NCT06745570

ACTIVE NOT RECRUITING 50 participants

Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study

University of Kansas Medical Center

NCT07008924

ACTIVE NOT RECRUITING NA 24 participants

Sleep Improvement Via Environmental Smart Temperature Adjustments

Hebrew SeniorLife

NCT06770400

ACTIVE NOT RECRUITING NA 20 participants

Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine

Washington University School of Medicine

NCT04206059

COMPLETED NA 2,562 participants

Intern Health Study 2022 and 2023

University of Michigan

NCT05436145

COMPLETED Phase 3 1,105 participants

Apnea Positive Pressure Long-Term Efficacy Study

Stanford University

NCT00051363

COMPLETED Phase 2 522 participants

Investigation of Sleep in the Intensive Care Unit

Massachusetts General Hospital

NCT03355053

COMPLETED 204 participants

VISC-Q Trial (Validation of an Online Sleep Characterization Questionnaire)

Philips Respironics

NCT03590795

COMPLETED NA 180 participants

Impact of Sleep Workshops in College Students

NYU Langone Health

NCT02665247

COMPLETED NA 176 participants

A Study to Assess the Effects of Dietary Supplement Drinks on Sleep, Stress and Mood

The Water Street Collective

NCT06378567

COMPLETED NA 149 participants

Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors-Renewal

Temple University

NCT03186508

COMPLETED Phase 2 140 participants

Hangover, Congeners, Sleep and Occupational Performance

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT00247585

COMPLETED NA 134 participants

Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness

Stanford University

NCT06001697

COMPLETED Phase 1 129 participants

A Personalized Behavioral Intervention to Improve Physical Activity, Sleep and Cognition in Sedentary Older Adults

Johns Hopkins University

NCT03959202

COMPLETED NA 120 participants

A Study to Evaluate the Effect of SlimBiotics Probiotic Formula on Weight Management and Metabolic Health Outcomes

Slimbiotics

NCT05917314

COMPLETED 119 participants

Examining the Biological Factors That Affect Sleep Duration

Brigham and Women's Hospital

NCT00607204

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Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 8
Phase 3 3
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Sleep Trial Landscape

152 indexed Sleep studies · 73 recruiting (48%).

Phase mix: 7 late (III/IV) vs 15 early (I/II).

Top sponsor: University of Pittsburgh (10 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Sleep?

PlainTrial tracks 152 US clinical trials for Sleep, of which 73 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Sleep?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.