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NCT04737200 · ClinicalTrials.gov registry record · NA
The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
A NA study of Sleep and Glucose Intolerance, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT04737200: Recruiting NA study of Sleep and Glucose Intolerance, sponsored by Massachusetts General Hospital.
NCT04737200 is a NA study of Sleep and Glucose Intolerance that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 30 participants, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04737200, a NA study of Sleep and Glucose Intolerance, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadian rhythms, and improves overall inflammation and cardiometabolic profiles in postoperative patients in the cardiac surgical ICU on enteral nutrition.
Primary Outcome
Sleep fragmentation is defined as the number of shifts from deeper (N2, N3, REM) to lighter (W or N1) sleep stages by hours of sleep. Sleep fragmentation will be assessed objectively through EEG measures.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Time-of-day of enteral nutrition provision (daytime first)
- DIETARY_SUPPLEMENT Time-of-day of enteral nutrition provision (nighttime first)
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2022-02-08 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
What NCT04737200 shows while recruiting
NCT04737200 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Sleep appearing as the primary indexed condition, and to 2 interventions - of which Time-of-day of enteral nutrition provision (daytime first) is the first listed.
NCT04737200 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04737200 about?
NCT04737200 is a clinical study titled "The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU". The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadian rhythms, and improves overall inflammation and cardiometabolic profiles in postoperative patients in the cardiac surgical ICU on enteral n...
What is the current status of trial NCT04737200?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2022-02-08. Estimated completion is 2026-03-31.
What conditions does trial NCT04737200 study?
This clinical trial studies the following conditions: Sleep, Glucose Intolerance, Feeding Patterns.
What interventions are being tested in trial NCT04737200?
The interventions under investigation include: Time-of-day of enteral nutrition provision (daytime first) (DIETARY_SUPPLEMENT), Time-of-day of enteral nutrition provision (nighttime first) (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04737200?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04737200 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04737200's enrollment target sits among peer trials
30 124th of 151 higher than 26 of 151 other Sleep trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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