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NCT00051363 · ClinicalTrials.gov registry record · Phase 3
Apnea Positive Pressure Long-Term Efficacy Study
A Phase 3 study of Sleep and Lung Diseases, sponsored by Stanford University.
- Completed
- Registry status
- Phase 3
- Development phase
- 1,105
- Enrollment target
- 5
- Study locations
NCT00051363: Completed Phase 3 study of Sleep and Lung Diseases, sponsored by Stanford University.
NCT00051363 is a Phase 3 study of Sleep and Lung Diseases that has completed, run by Stanford University. The registered enrollment target is 1,105 participants, below the 4,159-participant average among 151 other Sleep trials with a reported enrollment target (73% lower). The trial reports 5 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00051363, a Phase 3 study of Sleep and Lung Diseases, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 1,105 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this study is to determine the effectiveness of nasal continuous positive airway pressure (CPAP) therapy for the treatment of obstructive sleep apnea syndrome (OSAS).
Primary Outcome
There are three primary measures of neurocognitive function measured for APPLES, each representing a different domain: Executive and Frontal-lobe (E/F) Function- Sustained Working Memory Test Overall Mid-Day Index (SWMT-OMD), Attention and Psychomotor (A/P) Function- Pathfinder Number Test Total Time (PFN-TOTL), and Learning and Memory (L/M) Function- Buschke Selective Reminding Test Sum Recall (BSRT-SR). This is domain #1: Executive and Frontal-lobe (E/F) Function- Sustained Working Memory Tes
Conditions Studied
Interventions
- DEVICE Active CPAP
- DEVICE Sham CPAP
Study Locations (5)
Arizona
- University of Arizona AHSC - Tucson
California
- Stanford University School of Medicine - Palo Alto
Massachusetts
- Brigham & Women's Hospital - Boston
Missouri
- St. Luke's Hospital - Chesterfield
Washington
- St. Mary Medical Center - Walla Walla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,105 participants |
| Start Date | 2002-09 |
| Est. Completion | 2008-09 |
| Phase | Phase 3 |
What the finished NCT00051363 record still lists
NCT00051363 is an interventional study that assigns participants to a tested intervention. Its 1,105 participants enrollment target places it among the larger protocols in the corpus, below the 4,159-participant average among 151 other Sleep trials with a reported enrollment target (73% lower).
The record links to 3 conditions, with Sleep appearing as the primary indexed condition, and to 2 interventions - of which Active CPAP is the first listed.
NCT00051363 lists 5 locations in 5 states (Arizona, California, Massachusetts).
Frequently Asked Questions
What is clinical trial NCT00051363 about?
NCT00051363 is a clinical study titled "Apnea Positive Pressure Long-Term Efficacy Study". The purpose of this study is to determine the effectiveness of nasal continuous positive airway pressure (CPAP) therapy for the treatment of obstructive sleep apnea syndrome (OSAS).
What is the current status of trial NCT00051363?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,105 participants. The study started on 2002-09. Estimated completion is 2008-09.
What conditions does trial NCT00051363 study?
This clinical trial studies the following conditions: Sleep, Lung Diseases, Sleep Apnea Syndromes.
What interventions are being tested in trial NCT00051363?
The interventions under investigation include: Active CPAP (DEVICE), Sham CPAP (DEVICE).
Who is sponsoring clinical trial NCT00051363?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00051363 being conducted?
This trial has 5 study locations across Arizona, California, Massachusetts, Missouri, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00051363's enrollment target sits among peer trials
1,105 6th of 151 higher than 146 of 151 other Sleep trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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