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NCT04206059 · ClinicalTrials.gov registry record · NA
Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine
A NA study of Sleep and Sedation Complication, sponsored by Washington University School of Medicine.
- Active
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT04206059: Active NA study of Sleep and Sedation Complication, sponsored by Washington University School of Medicine.
NCT04206059 is a NA study of Sleep and Sedation Complication that is active but no longer recruiting, run by Washington University School of Medicine. The registered enrollment target is 20 participants, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04206059, a NA study of Sleep and Sedation Complication, is active but no longer recruiting, sponsored by Washington University School of Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Prospective within-subject study of dexmedetomidine sedation paired with CLAS conditions in repeated blocks. Intervention will consist of CLAS in-phase with EEG slow waves. Anti-phase stimulation will serve as an active control while sham stimulation will serve as a passive control.
Primary Outcome
EEG slow waves activity (power) relative to the timing of the stimulation. Values are log-transformed All participants serve in the same arm but experience both sham and in-phase blocks.
Conditions Studied
Interventions
- RADIATION MRI
- DIAGNOSTIC_TEST Quantitative Sensory Testing (QST)
- DIAGNOSTIC_TEST Home sleep study
- OTHER Acoustic stimulation (65db) up-slope of EEG with QST
- OTHER Acoustic stimulation (65db) down-slope of EEG with QST
Study Locations (1)
Missouri
- Washington University School of Medicine/Barnes-Jewish Hospital - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2021-01-20 |
| Est. Completion | 2023-07-01 |
| Phase | NA |
What the registry record for NCT04206059 still lists
NCT04206059 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Sleep appearing as the primary indexed condition, and to 5 interventions - of which MRI is the first listed.
NCT04206059 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT04206059 about?
NCT04206059 is a clinical study titled "Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine". Prospective within-subject study of dexmedetomidine sedation paired with CLAS conditions in repeated blocks. Intervention will consist of CLAS in-phase with EEG slow waves. Anti-phase stimulation will serve as an active control while sham stimulation will serve as a passive control.
What is the current status of trial NCT04206059?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2021-01-20. Estimated completion is 2023-07-01.
What conditions does trial NCT04206059 study?
This clinical trial studies the following conditions: Sleep, Sedation Complication.
What interventions are being tested in trial NCT04206059?
The interventions under investigation include: MRI (RADIATION), Quantitative Sensory Testing (QST) (DIAGNOSTIC_TEST), Home sleep study (DIAGNOSTIC_TEST), Acoustic stimulation (65db) up-slope of EEG with QST (OTHER), Acoustic stimulation (65db) down-slope of EEG with QST (OTHER).
Who is sponsoring clinical trial NCT04206059?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04206059 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04206059's enrollment target sits among peer trials
20 134th of 151 higher than 12 of 151 other Sleep trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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