Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 73 recruiting now early-phase tilt #74 of 28,707 conditions

Sleep: early-phase trial registry

73 of 152 indexed Sleep trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #74 of 28,707 conditions by registered trial count.

152 US clinical trials · 73 currently recruiting · #74 of 28,707 conditions by registered trial count

Sleep: 152 US clinical trials tracked, 73 recruiting.

Sleep is the subject of 152 registered US clinical trials on ClinicalTrials.gov, 73 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Pittsburgh, running 10 of these trials.

Enrollment posture brief

Registry condition sleep

OPEN 73 | RECR 48% | LATE 7 | EARLY 15 | RANK #74 | SPON 10

Nearest open-share peer: Alpha-1 Antitrypsin Deficiency (48% recruiting · 25 trials)

Cervical Cancer48.3%Sleep (this)48%Stress41.8%Insomnia40.8%Atopic Dermatitis36.4%
Open-enrollment share among volume-matched conditions near Sleep

Sleep lists 73 open slots (48% of 152 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Sleep on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Sleep is recruiting above its size-band peers.

    73 of 152 indexed trials (48%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Sleep trials is spread across many organizations.

    University of Pittsburgh accounts for 10 of 152 trials (6.6%). 96 distinct sponsors appear on at least one study for this condition label.

  3. Typical Sleep enrolment sits around 80 participants.

    Median target enrolment is 80 among the 152 trials that report a genuine target (sentinel values excluded). 84 of those (55.3%) plan for fewer than 100 participants.

  4. Sleep research is mostly interventional.

    134 interventional and 18 observational studies make up this index (88.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 28Phase 33Phase 44

Open and recent trials

152 total, page 3 of 4

COMPLETED NA 110 participants

StandUPTV: Reducing Sedentary Screen Time in Adults

Arizona State University

NCT04464993

COMPLETED NA 103 participants

Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors

The Miriam Hospital

NCT01508793

COMPLETED NA 98 participants

Comparing Acupuncture, BioModulator, and Transcutaneous Electrical Nerve Stimulation for Symptomatic Treatment of Chronic Pain.

Samueli Institute for Information Biology

NCT01752010

COMPLETED NA 96 participants

Mindfulness-Based College: Stage 1

Brown University

NCT03124446

COMPLETED NA 90 participants

Impact of Bed Provision and Sleep Education

Saint Joseph's University, Philadelphia

NCT04536766

COMPLETED NA 87 participants

Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers

Duke University

NCT01343810

COMPLETED NA 75 participants

The "PC-LIGHT" Study

Northwestern University

NCT03419585

COMPLETED NA 71 participants

Impact of Protein Quantity Within the USDA Healthy Style Eating Pattern on Sleep

Purdue University

NCT03174769

COMPLETED NA 70 participants

Tart Cherry Supplementation & Gut Microbiome and Inflammation

Ohio University

NCT04467372

COMPLETED NA 66 participants

Effect of Music and Other Audio Recordings for Chronic Pain in Aging Adults

Baylor University

NCT04785963

COMPLETED NA 65 participants

Teaching Healthy Responsive Parenting During Infancy to Promote Vital Growth and dEvelopment (THRIVE) Study

Children's Hospital Medical Center, Cincinnati

NCT04989738

COMPLETED NA 63 participants

Sleep Quality in High School Students With Asthma - II

Columbia University

NCT03329066

COMPLETED 56 participants

MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00117221

COMPLETED NA 54 participants

Treating Cancer-Related Fatigue Through Systematic Light Exposure

Icahn School of Medicine at Mount Sinai

NCT01873794

COMPLETED NA 54 participants

Cognitive Behavioral Treatment for Improving Sleep in Overweight and Obese Youth

University of Florida

NCT02232217

COMPLETED NA 53 participants

Relationship of Exercise, Sleep, and Inflammation Markers in People Living With HIV

Christine Horvat Davey

NCT04946994

COMPLETED NA 52 participants

Research on Improving Sleep During Pregnancy

University of California, San Francisco

NCT05017974

COMPLETED 50 participants

Sleep and Glucose Regulation in Youth With Type 1 Diabetes Mellitus

University of Arizona

NCT00848822

COMPLETED NA 47 participants

EaseAlert: Tactile Firefighter Alerting System

Embry-Riddle Aeronautical University

NCT05641194

COMPLETED NA 46 participants

Lower Extremity Splinting to Manage Pain and Sleep Disturbances Associated With HIV/AIDS Related Peripheral Neuropathy

Texas Woman's University

NCT01419314

COMPLETED NA 45 participants

WatchPAT Device Validation Study Compared to Polysomnography

University of Colorado, Denver

NCT03188718

COMPLETED 36 participants

Addressing Health Disparities in African Americans - Exploring Sleep and Developing Interventions

Pennington Biomedical Research Center

NCT05102175

COMPLETED 36 participants

Sleep Quality in High School Students With Asthma

Columbia University

NCT03073187

COMPLETED NA 35 participants

Study to Evaluate the Efficacy of Asystems' Complete Calm Supplementation on Sleep Quality and Duration, Anxiety, and Stress

Asystem

NCT05190640

COMPLETED NA 35 participants

The Effect of Sleep Extension in Teenage Girls at a College Preparatory High School

Medical College of Wisconsin

NCT04285307

COMPLETED Phase 1 33 participants

Bright Light: A Novel Treatment for Anxiety

University of South Carolina

NCT01064700

COMPLETED NA 33 participants

Efficacy of Clinical Decision Support and Sleep Navigation (Sleep PASS)

Children's Hospital of Philadelphia

NCT05353998

COMPLETED 32 participants

Sleep During Weight Loss and Weight Loss Maintenance

Dartmouth-Hitchcock Medical Center

NCT03774563

COMPLETED NA 32 participants

A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products

Clevr Blends

NCT06146517

COMPLETED NA 31 participants

The Effects of Bright Light Exposure on ICU Nurses

University of Pittsburgh

NCT03331822

COMPLETED NA 31 participants

Project MiCRIM- Sleep and Stress Intervention

Florida State University

NCT05384067

COMPLETED NA 31 participants

Whey Protein Supplementation in High School Athletes

University of Utah

NCT05589129

COMPLETED NA 30 participants

The Effects of Mindfulness Meditation on Sleep Quality and Perceived Stress

University of the Sciences in Philadelphia

NCT05253092

COMPLETED NA 26 participants

Reinstatement of Context During Sleep and Its Subsequent Effect on Memory: an fMRI Study

Northwestern University

NCT04702724

COMPLETED Phase 4 26 participants

Hypnotic Medications and Memory: Effect of Drug Exposure During the Night

St. Luke's Hospital, Chesterfield, Missouri

NCT01159652

COMPLETED NA 25 participants

Bedtime Stories: A Sleep Health Education Program for Healthcare Providers

Boston Children's Hospital

NCT06455579

COMPLETED NA 23 participants

Reactivating Specific Memories During Sleep in Conjunction with a Suppression Context

Northwestern University

NCT04702750

COMPLETED 20 participants

Glucose Metabolism and Sleep in People With Family History of Type 2 Diabetes.

University of Chicago

NCT00720889

COMPLETED Early Phase 1 20 participants

Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude.

University of California, San Diego

NCT03368352

COMPLETED 20 participants

Synovial Fluid Sleep Study

NYU Langone Health

NCT04688099

COMPLETED Phase 4 19 participants

The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia

Mansoor Ahmed M.D.

NCT01234675

COMPLETED NA 16 participants

Sleep Promotion Program Primary Care (SPP PC) Open Trial

University of Pittsburgh

NCT06239792

COMPLETED NA 15 participants

Implementing Behavioral Sleep Intervention in Urban Primary Care

Children's Hospital of Philadelphia

NCT04046341

COMPLETED NA 15 participants

Kavalactones on Sleep and Cortisol in Healthy Special Forces Trainees

Thorne HealthTech

NCT05381025

COMPLETED NA 14 participants

Treating Sleep in Teens With ADHD

Children's Hospital Medical Center, Cincinnati

NCT04270812

COMPLETED Early Phase 1 13 participants

Electrical Synchronization of Slow Oscillations to Enhance Deep Sleep

Brain Electrophysiology Laboratory Company

NCT04461769

COMPLETED NA 13 participants

A Combined School- and Home-Based Sleep Promotion Program

University of South Carolina

NCT06131944

COMPLETED NA 10 participants

The Effect of Pre-Frontal tDCS on Sleep Propensity During an Afternoon Nap: RCT

Medical University of South Carolina

NCT02176785

COMPLETED NA 10 participants

First Responder Resiliency Program During COVID-19

Mayo Clinic

NCT04536376

COMPLETED NA 10 participants

Optimizing Sleep/Wake Related Cognitive Efficacy

Mayo Clinic

NCT02412410

← Previous Page 3 of 4 Next →

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 8
Phase 3 3
Phase 4 4

Named interventions

Most-linked intervention names on Sleep records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
7 trials
Targeted memory reactivation (sounds) Behavioral
2 trials
Rested & Ready to Learn Behavioral
2 trials
Intern Health Study behavioral change mobile notification Behavioral
2 trials
Sleep Behavioral
2 trials
Transcranial Electrical Stimulation Device
2 trials
Sleep Extension Behavioral
2 trials
Regularized Sleep Schedule Behavioral
2 trials

US sites by state

Facility locations filed on Sleep trials. A trial with sites in several states counts in each.

Pennsylvania 21 trials
California 18 trials
Massachusetts 17 trials
New York 11 trials
Rhode Island 9 trials
Texas 8 trials
Maryland 8 trials
Ohio 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Sleep page

152 registered trials, 73 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Sleep condition card totals 152 registered trials; most-linked intervention Placebo; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.