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ClinicalTrials.gov 73 recruiting now official registry

Sleep clinical trials

73 of 152 indexed Sleep trials are currently recruiting.

152 US clinical trials · 73 currently recruiting

Sleep is the subject of 152 registered US clinical trials on ClinicalTrials.gov, 73 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Pittsburgh, running 10 of these trials.

The research picture

Sleep has 152 registered US clinical trials, 73 of them open to new participants right now, about 48% of the total.

73
recruiting participants now
48%
of trials open to enrollment
7
in Phase 3–4 (later-stage)
10
top sponsor: University of Pittsburgh
Phase 17Phase 28Phase 33Phase 44

Active & Recent Trials

152 total, page 3 of 4

COMPLETED NA 110 participants

StandUPTV: Reducing Sedentary Screen Time in Adults

Arizona State University

NCT04464993

COMPLETED NA 103 participants

Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors

The Miriam Hospital

NCT01508793

COMPLETED NA 98 participants

Comparing Acupuncture, BioModulator, and Transcutaneous Electrical Nerve Stimulation for Symptomatic Treatment of Chronic Pain.

Samueli Institute for Information Biology

NCT01752010

COMPLETED NA 96 participants

Mindfulness-Based College: Stage 1

Brown University

NCT03124446

COMPLETED NA 90 participants

Impact of Bed Provision and Sleep Education

Saint Joseph's University, Philadelphia

NCT04536766

COMPLETED NA 87 participants

Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers

Duke University

NCT01343810

COMPLETED NA 75 participants

The "PC-LIGHT" Study

Northwestern University

NCT03419585

COMPLETED NA 71 participants

Impact of Protein Quantity Within the USDA Healthy Style Eating Pattern on Sleep

Purdue University

NCT03174769

COMPLETED NA 70 participants

Tart Cherry Supplementation & Gut Microbiome and Inflammation

Ohio University

NCT04467372

COMPLETED NA 66 participants

Effect of Music and Other Audio Recordings for Chronic Pain in Aging Adults

Baylor University

NCT04785963

COMPLETED NA 65 participants

Teaching Healthy Responsive Parenting During Infancy to Promote Vital Growth and dEvelopment (THRIVE) Study

Children's Hospital Medical Center, Cincinnati

NCT04989738

COMPLETED NA 63 participants

Sleep Quality in High School Students With Asthma - II

Columbia University

NCT03329066

COMPLETED 56 participants

MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00117221

COMPLETED NA 54 participants

Treating Cancer-Related Fatigue Through Systematic Light Exposure

Icahn School of Medicine at Mount Sinai

NCT01873794

COMPLETED NA 54 participants

Cognitive Behavioral Treatment for Improving Sleep in Overweight and Obese Youth

University of Florida

NCT02232217

COMPLETED NA 53 participants

Relationship of Exercise, Sleep, and Inflammation Markers in People Living With HIV

Christine Horvat Davey

NCT04946994

COMPLETED NA 52 participants

Research on Improving Sleep During Pregnancy

University of California, San Francisco

NCT05017974

COMPLETED 50 participants

Sleep and Glucose Regulation in Youth With Type 1 Diabetes Mellitus

University of Arizona

NCT00848822

COMPLETED NA 47 participants

EaseAlert: Tactile Firefighter Alerting System

Embry-Riddle Aeronautical University

NCT05641194

COMPLETED NA 46 participants

Lower Extremity Splinting to Manage Pain and Sleep Disturbances Associated With HIV/AIDS Related Peripheral Neuropathy

Texas Woman's University

NCT01419314

COMPLETED NA 45 participants

WatchPAT Device Validation Study Compared to Polysomnography

University of Colorado, Denver

NCT03188718

COMPLETED 36 participants

Addressing Health Disparities in African Americans - Exploring Sleep and Developing Interventions

Pennington Biomedical Research Center

NCT05102175

COMPLETED 36 participants

Sleep Quality in High School Students With Asthma

Columbia University

NCT03073187

COMPLETED NA 35 participants

Study to Evaluate the Efficacy of Asystems' Complete Calm Supplementation on Sleep Quality and Duration, Anxiety, and Stress

Asystem

NCT05190640

COMPLETED NA 35 participants

The Effect of Sleep Extension in Teenage Girls at a College Preparatory High School

Medical College of Wisconsin

NCT04285307

COMPLETED Phase 1 33 participants

Bright Light: A Novel Treatment for Anxiety

University of South Carolina

NCT01064700

COMPLETED NA 33 participants

Efficacy of Clinical Decision Support and Sleep Navigation (Sleep PASS)

Children's Hospital of Philadelphia

NCT05353998

COMPLETED 32 participants

Sleep During Weight Loss and Weight Loss Maintenance

Dartmouth-Hitchcock Medical Center

NCT03774563

COMPLETED NA 32 participants

A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products

Clevr Blends

NCT06146517

COMPLETED NA 31 participants

The Effects of Bright Light Exposure on ICU Nurses

University of Pittsburgh

NCT03331822

COMPLETED NA 31 participants

Project MiCRIM- Sleep and Stress Intervention

Florida State University

NCT05384067

COMPLETED NA 31 participants

Whey Protein Supplementation in High School Athletes

University of Utah

NCT05589129

COMPLETED NA 30 participants

The Effects of Mindfulness Meditation on Sleep Quality and Perceived Stress

University of the Sciences in Philadelphia

NCT05253092

COMPLETED NA 26 participants

Reinstatement of Context During Sleep and Its Subsequent Effect on Memory: an fMRI Study

Northwestern University

NCT04702724

COMPLETED Phase 4 26 participants

Hypnotic Medications and Memory: Effect of Drug Exposure During the Night

St. Luke's Hospital, Chesterfield, Missouri

NCT01159652

COMPLETED NA 25 participants

Bedtime Stories: A Sleep Health Education Program for Healthcare Providers

Boston Children's Hospital

NCT06455579

COMPLETED NA 23 participants

Reactivating Specific Memories During Sleep in Conjunction with a Suppression Context

Northwestern University

NCT04702750

COMPLETED 20 participants

Glucose Metabolism and Sleep in People With Family History of Type 2 Diabetes.

University of Chicago

NCT00720889

COMPLETED Early Phase 1 20 participants

Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude.

University of California, San Diego

NCT03368352

COMPLETED 20 participants

Synovial Fluid Sleep Study

NYU Langone Health

NCT04688099

COMPLETED Phase 4 19 participants

The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia

Mansoor Ahmed M.D.

NCT01234675

COMPLETED NA 16 participants

Sleep Promotion Program Primary Care (SPP PC) Open Trial

University of Pittsburgh

NCT06239792

COMPLETED NA 15 participants

Implementing Behavioral Sleep Intervention in Urban Primary Care

Children's Hospital of Philadelphia

NCT04046341

COMPLETED NA 15 participants

Kavalactones on Sleep and Cortisol in Healthy Special Forces Trainees

Thorne HealthTech

NCT05381025

COMPLETED NA 14 participants

Treating Sleep in Teens With ADHD

Children's Hospital Medical Center, Cincinnati

NCT04270812

COMPLETED Early Phase 1 13 participants

Electrical Synchronization of Slow Oscillations to Enhance Deep Sleep

Brain Electrophysiology Laboratory Company

NCT04461769

COMPLETED NA 13 participants

A Combined School- and Home-Based Sleep Promotion Program

University of South Carolina

NCT06131944

COMPLETED NA 10 participants

The Effect of Pre-Frontal tDCS on Sleep Propensity During an Afternoon Nap: RCT

Medical University of South Carolina

NCT02176785

COMPLETED NA 10 participants

First Responder Resiliency Program During COVID-19

Mayo Clinic

NCT04536376

COMPLETED NA 10 participants

Optimizing Sleep/Wake Related Cognitive Efficacy

Mayo Clinic

NCT02412410

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Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 8
Phase 3 3
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Sleep Trial Landscape

152 indexed Sleep studies · 73 recruiting (48%).

Phase mix: 7 late (III/IV) vs 15 early (I/II).

Top sponsor: University of Pittsburgh (10 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Sleep?

PlainTrial tracks 152 US clinical trials for Sleep, of which 73 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Sleep?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.