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NCT05771844 · ClinicalTrials.gov registry record · NA

Home Sleep Therapy for Older Adults With MCI

A NA study of Mild Cognitive Impairment and Sleep, sponsored by Brain Electrophysiology Laboratory Company.

Recruiting
Registry status
NA
Development phase
60
Enrollment target
2
Study locations

NCT05771844: Recruiting NA study of Mild Cognitive Impairment and Sleep, sponsored by Brain Electrophysiology Laboratory Company.

NCT05771844 is a NA study of Mild Cognitive Impairment and Sleep that is actively recruiting participants, run by Brain Electrophysiology Laboratory Company. The registered enrollment target is 60 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (95% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05771844, a NA study of Mild Cognitive Impairment and Sleep, is actively recruiting participants, sponsored by Brain Electrophysiology Laboratory Company.

RECRUITING
Registry status
NA
Development phase
60 participants
Enrollment target
2
Study locations

Study Summary

The goal of this clinical trial is to learn about the ability of non-invasive brain stimulation during sleep to enhance people's deep sleep and its potential benefit on memory in people with mild cognitive impairment via home use sleep therapy device (SleepWISP) as well as learn about biomarkers associated with Alzheimer disease (AD). The clinical trial aims to answer the following main questions: 1. Whether the non-invasive transcranial electrical stimulation (TES) delivered by SleepWISP could provide short-term enhancement of deep sleep in a single night in the target population. 2. Whether TES delivered by SleepWISP could enhance deep sleep over multiple nights in the target population. 3. Whether enhance on deep sleep could improve memory performance in the target population. Participants will be asked to wear non-invasive and painless devices that record their brain activity during sleep along with an actigraphy watch that measures their movement throughout the day. In addition, blood samples or nasal swab assays will be collected from participants multiple times during the study.

Primary Outcome

Criteria for success: the prototype is safe for all participants, and it is usable at home by 80% of adults with MCI. Specific outcome ratings (5-point Lickert scale) will be obtained for (1) ability to clean the device, (2) ability to apply the device, (3) ability to turn on the tablet (launching the dedicated software); (4) ability to start treatment; (5) ability to complete treatment.

Conditions Studied

Mild Cognitive Impairment Sleep Memory Transcranial Electrical Stimulation Machine Learning

Interventions

  • DEVICE Transcranial Electrical Stimulation

Study Locations (2)

North Carolina

  • Wake Forest University - Winston-Salem

Oregon

  • Brain Electrophysiology Laboratory Company - Eugene

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2023-02-08
Est. Completion 2026-06-01
Phase NA
Brain Electrophysiology Laboratory Company

2 total trials

What NCT05771844 shows while recruiting

NCT05771844 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (95% lower).

The record links to 5 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Electrical Stimulation is the first listed.

NCT05771844 reports a single indexed study location in North Carolina, Oregon.

Frequently Asked Questions

What is clinical trial NCT05771844 about?

NCT05771844 is a clinical study titled "Home Sleep Therapy for Older Adults With MCI". The goal of this clinical trial is to learn about the ability of non-invasive brain stimulation during sleep to enhance people's deep sleep and its potential benefit on memory in people with mild cognitive impairment via home use sleep therapy device (SleepWISP) as well as learn about biomarkers ass...

What is the current status of trial NCT05771844?

This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2023-02-08. Estimated completion is 2026-06-01.

What conditions does trial NCT05771844 study?

This clinical trial studies the following conditions: Mild Cognitive Impairment, Sleep, Memory, Transcranial Electrical Stimulation, Machine Learning.

What interventions are being tested in trial NCT05771844?

The interventions under investigation include: Transcranial Electrical Stimulation (DEVICE).

Who is sponsoring clinical trial NCT05771844?

This trial is sponsored by Brain Electrophysiology Laboratory Company, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05771844 being conducted?

This trial has 2 study locations across North Carolina, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Mild Cognitive Impairment

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05771844's enrollment target sits among peer trials

60 124th of 205 higher than 73 of 205 other Mild Cognitive Impairment trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT05771844

Source: ClinicalTrials.gov NCT05771844, the US trial registry maintained by the National Library of Medicine. NCT05771844 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.