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ClinicalTrials.gov 7 recruiting now official registry

Retinoblastoma clinical trials

7 of 16 indexed Retinoblastoma trials are currently recruiting.

16 US clinical trials · 7 currently recruiting

Retinoblastoma is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 4 of these trials.

The research picture

Retinoblastoma has 16 registered US clinical trials, 7 of them open to new participants right now, about 44% of the total.

7
recruiting participants now
44%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
4
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 15Phase 25

Active & Recent Trials

16 total, page 1 of 1

RECRUITING 6,035 participants

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

National Cancer Institute (NCI)

NCT01109394

RECRUITING 900 participants

Studying Health Outcomes After Treatment in Patients With Retinoblastoma

Vanderbilt-Ingram Cancer Center

NCT03932786

RECRUITING 800 participants

RB Liquid Biopsy Biorepository

Children's Hospital Los Angeles

NCT04959097

RECRUITING 100 participants

Detailed Phenotypic and Genotype Study to Correlate RB1 Mutations Relating to Primary Ocular Tumors and Secondary Extra-ocular Metastasis.

University of Washington

NCT06725173

RECRUITING 75 participants

Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients

Memorial Sloan Kettering Cancer Center

NCT03546387

RECRUITING Phase 1 45 participants

GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma

Stephan Grupp MD PhD

NCT05650749

RECRUITING Phase 2 30 participants

Retinoblastoma Phase II Expanded Access Clinical Trial

Targeted Therapy Technologies

NCT06679634

ACTIVE NOT RECRUITING 473 participants

Retinoblastoma Survivor Study: Assessment of General Health and Quality of Life

Memorial Sloan Kettering Cancer Center

NCT00639301

ACTIVE NOT RECRUITING Phase 2 174 participants

Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

St. Jude Children's Research Hospital

NCT01783535

ACTIVE NOT RECRUITING Phase 1 68 participants

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

NCT04483778

ACTIVE NOT RECRUITING Phase 1 44 participants

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

NCT03618381

COMPLETED Phase 2 50 participants

Chemotherapy in Treating Patients With Retinoblastoma

Memorial Sloan Kettering Cancer Center

NCT00002675

COMPLETED Phase 2 30 participants

Chemotherapy Treatment for Children With Intraocular Germ-Line Retinoblastoma

Ann & Robert H Lurie Children's Hospital of Chicago

NCT00179920

COMPLETED Phase 1 28 participants

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Pediatric Brain Tumor Consortium

NCT00006246

COMPLETED Phase 2 22 participants

Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00024258

COMPLETED Phase 1 18 participants

Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors

Emory University

NCT01331135

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Retinoblastoma Trial Landscape

16 indexed Retinoblastoma studies · 7 recruiting (44%).

Phase mix: 0 late (III/IV) vs 10 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (4 trials), 9 others listed. 16 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Retinoblastoma?

PlainTrial tracks 16 US clinical trials for Retinoblastoma, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Retinoblastoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.