Pediatric Brain Tumor Consortium
Pediatric Brain Tumor Consortium sponsors 27 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 12 completed. 0 of these trials are in Phase 3-4 (later-stage) and 24 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Brain and Central Nervous System Tumors, with 4 trials.
Trial Pipeline
27 total, page 1 of 1
131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma
NCT04743661
A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration
NCT04201457
Phase I Study of APX005M in Pediatric Central Nervous System Tumors
NCT03389802
Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors
NCT05934630
INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas
NCT04295759
Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery
NCT03904862
Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors
NCT03387020
Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma
NCT02717455
Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors
NCT02255461
Peginterferon Alfa-2b in Younger Patients With Craniopharyngioma That is Recurrent or Cannot Be Removed By Surgery
NCT01964300
Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery
NCT02031965
p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors
NCT01975116
Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors
NCT01836549
PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors
NCT01158300
MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer
NCT00572182
Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors
NCT00503724
Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma
NCT00357253
Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors
NCT00112619
VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors
NCT00098761
TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma
NCT00074334
Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma
NCT00045721
Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor
NCT00047177
SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors
NCT00015899
Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children
NCT00010114
Genetic Study of Brain Tumors in Young Children
NCT00010101
Busulfan in Treating Children and Adolescents With Refractory CNS Cancer
NCT00006246
SU5416 in Treating Children With Recurrent or Progressive Brain Tumors
NCT00006247
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 20 |
| Phase 2 | 4 |
Therapeutic Areas
What the Pipeline for Pediatric Brain Tumor Consortium Shows
According to the ClinicalTrials.gov registry, Pediatric Brain Tumor Consortium is linked to 27 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 12 are already marked complete, representing roughly 44% of the total.
The phase mix for Pediatric Brain Tumor Consortium reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 24 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Pediatric Brain Tumor Consortium is Brain and Central Nervous System Tumors with 4 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.