Pediatric Brain Tumor Consortium

27 total trials 12 completed

Pediatric Brain Tumor Consortium sponsors 27 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 12 completed. 0 of these trials are in Phase 3-4 (later-stage) and 24 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Brain and Central Nervous System Tumors, with 4 trials.

Trial Pipeline

27 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 2

131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma

NCT04743661

ACTIVE NOT RECRUITING Phase 1

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

NCT04201457

ACTIVE NOT RECRUITING Phase 1

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

NCT03389802

TERMINATED

Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors

NCT05934630

COMPLETED Phase 1

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

NCT04295759

TERMINATED Phase 1

Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery

NCT03904862

COMPLETED Phase 1

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

NCT03387020

COMPLETED Phase 1

Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma

NCT02717455

TERMINATED Phase 1

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

NCT02255461

TERMINATED Phase 2

Peginterferon Alfa-2b in Younger Patients With Craniopharyngioma That is Recurrent or Cannot Be Removed By Surgery

NCT01964300

TERMINATED Phase 1

Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery

NCT02031965

COMPLETED Phase 1

p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors

NCT01975116

TERMINATED Phase 2

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

NCT01836549

COMPLETED Phase 1

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

NCT01158300

TERMINATED Phase 1

MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer

NCT00572182

COMPLETED Phase 1

Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors

NCT00503724

COMPLETED Phase 1

Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma

NCT00357253

TERMINATED Phase 1

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

NCT00112619

COMPLETED Phase 1

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

NCT00098761

TERMINATED Phase 1

TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma

NCT00074334

TERMINATED Phase 1

Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma

NCT00045721

COMPLETED Phase 2

Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor

NCT00047177

COMPLETED Phase 1

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

NCT00015899

COMPLETED

Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children

NCT00010114

TERMINATED

Genetic Study of Brain Tumors in Young Children

NCT00010101

COMPLETED Phase 1

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

NCT00006246

TERMINATED Phase 1

SU5416 in Treating Children With Recurrent or Progressive Brain Tumors

NCT00006247

What the Pipeline for Pediatric Brain Tumor Consortium Shows

According to the ClinicalTrials.gov registry, Pediatric Brain Tumor Consortium is linked to 27 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 12 are already marked complete, representing roughly 44% of the total.

The phase mix for Pediatric Brain Tumor Consortium reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 24 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Pediatric Brain Tumor Consortium is Brain and Central Nervous System Tumors with 4 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.