Pediatric Brain Tumor Consortium
Closed portfolio with an early-phase archive tilt
According to ClinicalTrials.gov-derived indexes, Pediatric Brain Tumor Consortium sits in the top decile of US sponsors by registered trial count (#583 of 15,742 sponsors by registered trial count).
Pediatric Brain Tumor Consortium: 27 sponsored US clinical trials, none currently recruiting.
Pediatric Brain Tumor Consortium sponsors 27 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 12 completed. 0 of these trials are in Phase 3-4 (later-stage) and 24 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Brain and Central Nervous System Tumors, with 4 trials.
Top-decile sponsor footprint
Pediatric Brain Tumor Consortium ranks in the top decile of sponsors by registered trial count (#583 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
12 of 24 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (50.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Indexed trials (enrollment closed)
27 total, page 1 of 1
131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma
NCT04743661
A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration
NCT04201457
Phase I Study of APX005M in Pediatric Central Nervous System Tumors
NCT03389802
Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors
NCT05934630
INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas
NCT04295759
Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery
NCT03904862
Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors
NCT03387020
Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma
NCT02717455
Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors
NCT02255461
Peginterferon Alfa-2b in Younger Patients With Craniopharyngioma That is Recurrent or Cannot Be Removed By Surgery
NCT01964300
Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery
NCT02031965
p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors
NCT01975116
Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors
NCT01836549
PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors
NCT01158300
MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer
NCT00572182
Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors
NCT00503724
Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma
NCT00357253
Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors
NCT00112619
VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors
NCT00098761
TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma
NCT00074334
Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma
NCT00045721
Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor
NCT00047177
SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors
NCT00015899
Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children
NCT00010114
Genetic Study of Brain Tumors in Young Children
NCT00010101
Busulfan in Treating Children and Adolescents With Refractory CNS Cancer
NCT00006246
SU5416 in Treating Children With Recurrent or Progressive Brain Tumors
NCT00006247
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 20 |
| Phase 2 | 4 |
Therapeutic Areas
How the Pediatric Brain Tumor Consortium early-phase archive is shaped
27 indexed studies, none listed as recruiting (0% open); 12 completed (44%).
Phase mix: 0 late (III/IV) vs 24 early (I/II) (early-phase heavy).
Top condition: Brain and Central Nervous System Tumors (4 trials), 9 others listed.
How to read a closed sponsor archive
When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.
Pediatric Brain Tumor Consortium: archived-pipeline peers nationwide
Peers matched on 27 indexed studies with no current recruiting: volume and archive shape, not condition overlap.
Pediatric Brain Tumor Consortium sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 27 archived trials
- Akron Children's Hospital · 27 trials · 7% recruiting
- ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) · 27 trials · 0% recruiting
- AVEO Pharmaceuticals · 27 trials · 7% recruiting
- Dompé Farmaceutici S.p.A · 27 trials · 15% recruiting
Sponsors with similar archive density (± trial count)
- 10xBio · 0% recruiting · 3 trials
- 22nd Century Group · 0% recruiting · 3 trials
- 23andMe · 0% recruiting · 6 trials
- 3-C Institute for Social Development · 0% recruiting · 14 trials
Related
What to do with this Pediatric Brain Tumor Consortium page
27 registered trials is a research-attention snapshot, not an endorsement of Pediatric Brain Tumor Consortium or any single study.
- None of Pediatric Brain Tumor Consortium's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
- Brain and Central Nervous System Tumors is the condition Pediatric Brain Tumor Consortium studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Brain and Central Nervous System Tumors trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Pediatric Brain Tumor Consortium pipeline card: 27 registered trials from official public datasets.Report a data error.