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NCT03546387 · ClinicalTrials.gov registry record
Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients
A clinical trial of Retinoblastoma and Pediatric Retinoblastoma, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- 75
- Enrollment target
- 1
- Study location
NCT03546387: Recruiting study of Retinoblastoma and Pediatric Retinoblastoma, sponsored by Memorial Sloan Kettering Cancer Center.
NCT03546387 is a study of Retinoblastoma and Pediatric Retinoblastoma that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 75 participants, below the 588-participant average among 15 other Retinoblastoma trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03546387, a study of Retinoblastoma and Pediatric Retinoblastoma, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.
Primary Outcome
The primary outcome is based on the Wechsler Intelligence Scale for Children, 5th edition (WISC-V) measured at follow up. The 5 primary index scores on the WISC-V (Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory, and Processing Speed) are based on 10 subtests and represent intellectual functioning in different cognitive areas. Similar to the FSIQ, the primary index scores are on a standard score metric with a mean of 100 (SD=15). The WISC-V consists of 16 subtests; each sub
Conditions Studied
Interventions
- OTHER Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V)
- OTHER California Verbal Learning Test, Children's Version
- OTHER Beery Developmental Test of Visual Motor Integration, 6th edition
- OTHER Grooved Pegboard Test
- OTHER Behavior Assessment System for Children/Parent Report
Study Locations (1)
New York
- Memorial Sloan Kettering Cancer Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2018-05-07 |
| Est. Completion | 2026-05-07 |
What NCT03546387 shows while recruiting
NCT03546387 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 588-participant average among 15 other Retinoblastoma trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Retinoblastoma appearing as the primary indexed condition, and to 5 interventions - of which Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V) is the first listed.
NCT03546387 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT03546387 about?
NCT03546387 is a clinical study titled "Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients". The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.
What is the current status of trial NCT03546387?
This trial is currently recruiting. The enrollment target is 75 participants. The study started on 2018-05-07. Estimated completion is 2026-05-07.
What conditions does trial NCT03546387 study?
This clinical trial studies the following conditions: Retinoblastoma, Pediatric Retinoblastoma.
What interventions are being tested in trial NCT03546387?
The interventions under investigation include: Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V) (OTHER), California Verbal Learning Test, Children's Version (OTHER), Beery Developmental Test of Visual Motor Integration, 6th edition (OTHER), Grooved Pegboard Test (OTHER), Behavior Assessment System for Children/Parent Report (OTHER).
Who is sponsoring clinical trial NCT03546387?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03546387 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03546387's enrollment target sits among peer trials
75 7th of 15 higher than 9 of 15 other Retinoblastoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Retinoblastoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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