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ClinicalTrials.gov 13 recruiting now official registry

Pulmonary Embolism clinical trials

Every US clinical trial registered for Pulmonary Embolism — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

49 US clinical trials · 13 currently recruiting

The research picture

Pulmonary Embolism has 49 registered US clinical trials, 13 of them open to new participants right now — about 27% of the total.

13
recruiting participants now
27%
of trials open to enrollment
9
in Phase 3–4 (later-stage)
5
top sponsor: Brigham and Women's Hospital

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 1,500 participants

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

Penumbra

NCT04798261

RECRUITING NA 1,200 participants

The PEERLESS II Study

Inari Medical

NCT06055920

RECRUITING 750 participants

Aspiration Thrombectomy Using the Symphony or Prodigy System

Imperative Care

NCT07350499

RECRUITING Phase 3 500 participants

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

NYU Langone Health

NCT05591118

RECRUITING 250 participants

Point-of-Care Ultrasound in Predicting Adverse Outcomes in Emergency Department Patients With Acute Pulmonary Embolism

WellSpan Health

NCT05050617

RECRUITING NA 230 participants

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

Brigham and Women's Hospital

NCT06538376

RECRUITING NA 200 participants

The PERSEVERE Study

Inari Medical

NCT06588634

RECRUITING NA 181 participants

Endovascular Engineering ENGULF Study

Endovascular Engineering

NCT05597891

RECRUITING NA 125 participants

CLEANer Aspiration for Pulmonary Embolism

Argon Medical Devices

NCT06189313

RECRUITING NA 107 participants

Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)

Innova Vascular

NCT06041594

RECRUITING NA 100 participants

A Study of Mobility Outcomes in Post-Pulmonary Embolic Disease

Mayo Clinic

NCT06695247

RECRUITING Early Phase 1 80 participants

Supplemental Oxygen in Pulmonary Embolism (SO-PE)

Massachusetts General Hospital

NCT05891886

RECRUITING NA 30 participants

Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery

Medical University of South Carolina

NCT06451003

ACTIVE NOT RECRUITING NA 854 participants

US Pivotal Clinical Study of the Adient Absorbable Filter for the Prevention of Pulmonary Embolism

Adient Medical

NCT05127915

ACTIVE NOT RECRUITING Phase 4 544 participants

Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism

Boston Scientific Corporation

NCT04790370

ACTIVE NOT RECRUITING Phase 3 417 participants

A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE

Anthos Therapeutics

NCT05171075

ACTIVE NOT RECRUITING NA 306 participants

Implementing Prescriber-Pharmacist Collaborative Care for Evidence-based Anticoagulant Use

University of Michigan

NCT05351749

ACTIVE NOT RECRUITING Phase 4 145 participants

Therapeutic Initial Heparin Dosing for Patients With Clots or Certain Heart Conditions Admitted to the Hospital

Inova Health Care Services

NCT07250763

ACTIVE NOT RECRUITING NA 130 participants

Aventus Thrombectomy System Pulmonary Embolism Clinical Study

Inquis Medical

NCT05907564

ACTIVE NOT RECRUITING NA 123 participants

Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion-II

Jupiter Endovascular

NCT06576427

ACTIVE NOT RECRUITING 115 participants

FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease

University of Texas Southwestern Medical Center

NCT04583878

ACTIVE NOT RECRUITING 63 participants

Comparing Electrical Impedance Tomography to Computed Tomographic Angiography

Colorado State University

NCT05546333

ACTIVE NOT RECRUITING Phase 4 31 participants

Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE

Northwell Health

NCT03581877

ACTIVE NOT RECRUITING NA 14 participants

Michigan Emergency Department Improvement Collaborative (MEDIC) Alert; Pulmonary Embolism (PE)

University of Michigan

NCT06312332

COMPLETED 98,947 participants

Replication of the EINSTEIN-PE Anticoagulant Trial in Healthcare Claims Data

Brigham and Women's Hospital

NCT04879407

COMPLETED NA 17,427 participants

Using a Real-Time Risk Prediction Model to Predict Pediatric Venous Thromboembolism (VTE) Events

Vanderbilt University Medical Center

NCT04574895

COMPLETED 10,679 participants

Global Anticoagulant Registry in the FIELD- Venous Thromboembolic Events

Thrombosis Research Institute

NCT02155491

COMPLETED 5,451 participants

Epidemiology of Venous Thromboembolism

Brigham and Women's Hospital

NCT00456196

COMPLETED 1,256 participants

Prospective Investigation of Pulmonary Embolism Diagnosis III

George Washington University

NCT00241826

COMPLETED Phase 4 1,110 participants

Comparison of Low and Intermediate Dose Low-molecular-weight Heparin to Prevent Recurrent Venous Thromboembolism in Pregnancy

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

NCT01828697

COMPLETED 935 participants

Short-term Clinical Deterioration After Acute Pulmonary Embolism

Wake Forest University Health Sciences

NCT03915925

COMPLETED NA 410 participants

D-dimer to Select Patients With First Unprovoked Venous Thromboembolism Who Can Have Anticoagulants Stopped at 3 Months

McMaster University

NCT00720915

COMPLETED NA 344 participants

Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information

Brigham and Women's Hospital

NCT00401414

COMPLETED 333 participants

Pulmonary Embolism Response to Fragmentation, Embolectomy, & Catheter Thrombolysis: PERFECT

Stanford University

NCT01097928

COMPLETED Phase 3 300 participants

Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism

Academic and Community Cancer Research United

NCT02585713

COMPLETED 300 participants

Evaluation of Obstructive Sleep Apnea as a Risk Factor for Pulmonary Embolism

Atlantic Health System

NCT00409045

COMPLETED 271 participants

Evaluation of the Accuracy and Precision of the INRatio® Prothrombin Time (PT) Monitoring System With New INRatio Test Strip Designed for Low Sample Volume and Heparin Insensitivity

Abbott RDx Cardiometabolic

NCT01037270

COMPLETED 213 participants

Accuracy of the D-Dimer Assay for the Exclusion of Pulmonary Embolism in a High Risk Oncologic Population

Memorial Sloan Kettering Cancer Center

NCT00615147

COMPLETED 200 participants

A Genomic Approach to Warfarin Dose Prescription in Admixed Caribbean Hispanics

University of Puerto Ri

NCT02345356

COMPLETED 130 participants

Identify Clinical Conditions That Increase Circulating DNA Levels

University of Florida

NCT01815996

COMPLETED Phase 4 120 participants

Detection of Pulmonary Embolism With CECT

Bracco Diagnostics

NCT00351754

COMPLETED Phase 3 109 participants

tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden

Thrombolex

NCT04248868

COMPLETED Phase 2 78 participants

Nitric Oxide to Treat Pulmonary Embolism

Indiana University School of Medicine

NCT01939301

COMPLETED NA 70 participants

Non-Interruptive Alerts for Improving Use of Clinical Decision Rules

University of Utah

NCT04702308

COMPLETED NA 40 participants

Once Daily Enoxaparin for Outpatient Treatment of Acute DVT and/or Pulmonary Embolism

Brigham and Women's Hospital

NCT00413374

COMPLETED NA 32 participants

Home Rehabilitation After Acute Pulmonary Embolism

University of Rochester

NCT05571189

COMPLETED Phase 1 25 participants

Phase I Trial of Inhaled Nitric Oxide to Treat Acute Pulmonary Embolism

Wake Forest University Health Sciences

NCT00848731

COMPLETED Phase 2 21 participants

Investigation Into the Therapeutic Dosage of Fondaparinux Sodium, a Medication Used to Prevent Blood Clots in Morbidly Obese Volunteers

University of Pittsburgh

NCT00436787

COMPLETED Phase 1 9 participants

First - In - Man Study to Assess the Safety and Feasibility of The Bashir™ Endovascular Catheter for the Treatment of Acute Pulmonary Embolism

Thrombolex

NCT03927508

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 4
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pulmonary Embolism Trial Landscape

ClinicalTrials.gov lists 49 US studies indexed under Pulmonary Embolism, and 13 of those are currently open to recruitment — roughly 27% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Pulmonary Embolism shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Pulmonary Embolism is led by Brigham and Women's Hospital with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 49 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pulmonary Embolism?

PlainTrial tracks 49 US clinical trials for Pulmonary Embolism, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pulmonary Embolism?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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