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ClinicalTrials.gov 13 recruiting now later-stage tilt

Pulmonary Embolism: later-stage trial registry

13 of 49 indexed Pulmonary Embolism trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #281 of 28,707 conditions by registered trial count.

49 US clinical trials · 13 currently recruiting · #281 of 28,707 conditions by registered trial count

Pulmonary Embolism: 49 US clinical trials tracked, 13 recruiting.

Pulmonary Embolism is the subject of 49 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 5 of these trials.

Enrollment posture brief

Registry condition pulmonary-embolism

OPEN 13 | RECR 27% | LATE 9 | EARLY 5 | RANK #281 | SPON 5

Nearest open-share peer: Hepatic Impairment (27% recruiting · 49 trials)

Diet, Healthy49%Duchenne Muscular Dystrophy44.9%Chronic Disease36.7%Arthritis30.6%Pulmonary Embolism (this)27%
Open-enrollment share among volume-matched conditions near Pulmonary Embolism

Pulmonary Embolism lists 13 open slots (27% of 49 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pulmonary Embolism on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pulmonary Embolism is recruiting below its size-band peers.

    13 of 49 indexed trials (26.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Pulmonary Embolism trials is spread across many organizations.

    Brigham and Women's Hospital accounts for 5 of 49 trials (10.2%). 41 distinct sponsors appear on at least one study for this condition label.

  3. Typical Pulmonary Embolism enrolment sits around 200 participants.

    Median target enrolment is 200 among the 49 trials that report a genuine target (sentinel values excluded). 12 of those (24.5%) plan for fewer than 100 participants.

  4. Pulmonary Embolism splits between interventional and observational designs.

    33 interventional and 16 observational studies make up this index (67.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 22Phase 34Phase 45

Open and recent trials

49 total, page 1 of 1

RECRUITING 1,500 participants

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

Penumbra

NCT04798261

RECRUITING NA 1,200 participants

The PEERLESS II Study

Inari Medical

NCT06055920

RECRUITING 750 participants

Aspiration Thrombectomy Using the Symphony or Prodigy System

Imperative Care

NCT07350499

RECRUITING Phase 3 500 participants

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

NYU Langone Health

NCT05591118

RECRUITING 250 participants

Point-of-Care Ultrasound in Predicting Adverse Outcomes in Emergency Department Patients With Acute Pulmonary Embolism

WellSpan Health

NCT05050617

RECRUITING NA 230 participants

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

Brigham and Women's Hospital

NCT06538376

RECRUITING NA 200 participants

The PERSEVERE Study

Inari Medical

NCT06588634

RECRUITING NA 181 participants

Endovascular Engineering ENGULF Study

Endovascular Engineering

NCT05597891

RECRUITING NA 125 participants

CLEANer Aspiration for Pulmonary Embolism

Argon Medical Devices

NCT06189313

RECRUITING NA 107 participants

Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)

Innova Vascular

NCT06041594

RECRUITING NA 100 participants

A Study of Mobility Outcomes in Post-Pulmonary Embolic Disease

Mayo Clinic

NCT06695247

RECRUITING Early Phase 1 80 participants

Supplemental Oxygen in Pulmonary Embolism (SO-PE)

Massachusetts General Hospital

NCT05891886

RECRUITING NA 30 participants

Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery

Medical University of South Carolina

NCT06451003

ACTIVE NOT RECRUITING NA 854 participants

US Pivotal Clinical Study of the Adient Absorbable Filter for the Prevention of Pulmonary Embolism

Adient Medical

NCT05127915

ACTIVE NOT RECRUITING Phase 4 544 participants

Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism

Boston Scientific Corporation

NCT04790370

ACTIVE NOT RECRUITING Phase 3 417 participants

A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE

Anthos Therapeutics

NCT05171075

ACTIVE NOT RECRUITING NA 306 participants

Implementing Prescriber-Pharmacist Collaborative Care for Evidence-based Anticoagulant Use

University of Michigan

NCT05351749

ACTIVE NOT RECRUITING Phase 4 145 participants

Therapeutic Initial Heparin Dosing for Patients With Clots or Certain Heart Conditions Admitted to the Hospital

Inova Health Care Services

NCT07250763

ACTIVE NOT RECRUITING NA 130 participants

Aventus Thrombectomy System Pulmonary Embolism Clinical Study

Inquis Medical

NCT05907564

ACTIVE NOT RECRUITING NA 123 participants

Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion-II

Jupiter Endovascular

NCT06576427

ACTIVE NOT RECRUITING 115 participants

FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease

University of Texas Southwestern Medical Center

NCT04583878

ACTIVE NOT RECRUITING 63 participants

Comparing Electrical Impedance Tomography to Computed Tomographic Angiography

Colorado State University

NCT05546333

ACTIVE NOT RECRUITING Phase 4 31 participants

Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE

Northwell Health

NCT03581877

ACTIVE NOT RECRUITING NA 14 participants

Michigan Emergency Department Improvement Collaborative (MEDIC) Alert; Pulmonary Embolism (PE)

University of Michigan

NCT06312332

COMPLETED 98,947 participants

Replication of the EINSTEIN-PE Anticoagulant Trial in Healthcare Claims Data

Brigham and Women's Hospital

NCT04879407

COMPLETED NA 17,427 participants

Using a Real-Time Risk Prediction Model to Predict Pediatric Venous Thromboembolism (VTE) Events

Vanderbilt University Medical Center

NCT04574895

COMPLETED 10,679 participants

Global Anticoagulant Registry in the FIELD- Venous Thromboembolic Events

Thrombosis Research Institute

NCT02155491

COMPLETED 5,451 participants

Epidemiology of Venous Thromboembolism

Brigham and Women's Hospital

NCT00456196

COMPLETED 1,256 participants

Prospective Investigation of Pulmonary Embolism Diagnosis III

George Washington University

NCT00241826

COMPLETED Phase 4 1,110 participants

Comparison of Low and Intermediate Dose Low-molecular-weight Heparin to Prevent Recurrent Venous Thromboembolism in Pregnancy

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

NCT01828697

COMPLETED 935 participants

Short-term Clinical Deterioration After Acute Pulmonary Embolism

Wake Forest University Health Sciences

NCT03915925

COMPLETED NA 410 participants

D-dimer to Select Patients With First Unprovoked Venous Thromboembolism Who Can Have Anticoagulants Stopped at 3 Months

McMaster University

NCT00720915

COMPLETED NA 344 participants

Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information

Brigham and Women's Hospital

NCT00401414

COMPLETED 333 participants

Pulmonary Embolism Response to Fragmentation, Embolectomy, & Catheter Thrombolysis: PERFECT

Stanford University

NCT01097928

COMPLETED Phase 3 300 participants

Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism

Academic and Community Cancer Research United

NCT02585713

COMPLETED 300 participants

Evaluation of Obstructive Sleep Apnea as a Risk Factor for Pulmonary Embolism

Atlantic Health System

NCT00409045

COMPLETED 271 participants

Evaluation of the Accuracy and Precision of the INRatio® Prothrombin Time (PT) Monitoring System With New INRatio Test Strip Designed for Low Sample Volume and Heparin Insensitivity

Abbott RDx Cardiometabolic

NCT01037270

COMPLETED 213 participants

Accuracy of the D-Dimer Assay for the Exclusion of Pulmonary Embolism in a High Risk Oncologic Population

Memorial Sloan Kettering Cancer Center

NCT00615147

COMPLETED 200 participants

A Genomic Approach to Warfarin Dose Prescription in Admixed Caribbean Hispanics

University of Puerto Ri

NCT02345356

COMPLETED 130 participants

Identify Clinical Conditions That Increase Circulating DNA Levels

University of Florida

NCT01815996

COMPLETED Phase 4 120 participants

Detection of Pulmonary Embolism With CECT

Bracco Diagnostics

NCT00351754

COMPLETED Phase 3 109 participants

tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden

Thrombolex

NCT04248868

COMPLETED Phase 2 78 participants

Nitric Oxide to Treat Pulmonary Embolism

Indiana University School of Medicine

NCT01939301

COMPLETED NA 70 participants

Non-Interruptive Alerts for Improving Use of Clinical Decision Rules

University of Utah

NCT04702308

COMPLETED NA 40 participants

Once Daily Enoxaparin for Outpatient Treatment of Acute DVT and/or Pulmonary Embolism

Brigham and Women's Hospital

NCT00413374

COMPLETED NA 32 participants

Home Rehabilitation After Acute Pulmonary Embolism

University of Rochester

NCT05571189

COMPLETED Phase 1 25 participants

Phase I Trial of Inhaled Nitric Oxide to Treat Acute Pulmonary Embolism

Wake Forest University Health Sciences

NCT00848731

COMPLETED Phase 2 21 participants

Investigation Into the Therapeutic Dosage of Fondaparinux Sodium, a Medication Used to Prevent Blood Clots in Morbidly Obese Volunteers

University of Pittsburgh

NCT00436787

COMPLETED Phase 1 9 participants

First - In - Man Study to Assess the Safety and Feasibility of The Bashir™ Endovascular Catheter for the Treatment of Acute Pulmonary Embolism

Thrombolex

NCT03927508

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 4
Phase 4 5

Named interventions

Most-linked intervention names on Pulmonary Embolism records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

The Bashir™ Endovascular Catheter Device
2 trials
r-tPA Drug
2 trials
Dalteparin Drug
2 trials
Warfarin Drug
2 trials
FlowTriever System Device
2 trials
Continue on anticoagulant therapy (positive d-dimer) Other
1 trials
Discontinue anticoagulant therapy (Negative d-dimer) Other
1 trials
Isovue Drug
1 trials

US sites by state

Facility locations filed on Pulmonary Embolism trials. A trial with sites in several states counts in each.

Florida 15 trials
New York 14 trials
Massachusetts 13 trials
Michigan 12 trials
Illinois 11 trials
Georgia 11 trials
California 11 trials
Pennsylvania 9 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pulmonary Embolism page

49 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pulmonary Embolism condition card totals 49 registered trials; most-linked intervention The Bashir™ Endovascular Catheter; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.