Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Pulmonary Embolism clinical trials
Every US clinical trial registered for Pulmonary Embolism — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
49 US clinical trials · 13 currently recruiting
The research picture
Pulmonary Embolism has 49 registered US clinical trials, 13 of them open to new participants right now — about 27% of the total.
- 13
- recruiting participants now
- 27%
- of trials open to enrollment
- 9
- in Phase 3–4 (later-stage)
- 5
- top sponsor: Brigham and Women's Hospital
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
Penumbra
NCT04798261
The PEERLESS II Study
Inari Medical
NCT06055920
Aspiration Thrombectomy Using the Symphony or Prodigy System
Imperative Care
NCT07350499
Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy
NYU Langone Health
NCT05591118
Point-of-Care Ultrasound in Predicting Adverse Outcomes in Emergency Department Patients With Acute Pulmonary Embolism
WellSpan Health
NCT05050617
Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU
Brigham and Women's Hospital
NCT06538376
The PERSEVERE Study
Inari Medical
NCT06588634
Endovascular Engineering ENGULF Study
Endovascular Engineering
NCT05597891
CLEANer Aspiration for Pulmonary Embolism
Argon Medical Devices
NCT06189313
Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)
Innova Vascular
NCT06041594
A Study of Mobility Outcomes in Post-Pulmonary Embolic Disease
Mayo Clinic
NCT06695247
Supplemental Oxygen in Pulmonary Embolism (SO-PE)
Massachusetts General Hospital
NCT05891886
Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery
Medical University of South Carolina
NCT06451003
US Pivotal Clinical Study of the Adient Absorbable Filter for the Prevention of Pulmonary Embolism
Adient Medical
NCT05127915
Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism
Boston Scientific Corporation
NCT04790370
A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE
Anthos Therapeutics
NCT05171075
Implementing Prescriber-Pharmacist Collaborative Care for Evidence-based Anticoagulant Use
University of Michigan
NCT05351749
Therapeutic Initial Heparin Dosing for Patients With Clots or Certain Heart Conditions Admitted to the Hospital
Inova Health Care Services
NCT07250763
Aventus Thrombectomy System Pulmonary Embolism Clinical Study
Inquis Medical
NCT05907564
Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion-II
Jupiter Endovascular
NCT06576427
FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease
University of Texas Southwestern Medical Center
NCT04583878
Comparing Electrical Impedance Tomography to Computed Tomographic Angiography
Colorado State University
NCT05546333
Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE
Northwell Health
NCT03581877
Michigan Emergency Department Improvement Collaborative (MEDIC) Alert; Pulmonary Embolism (PE)
University of Michigan
NCT06312332
Replication of the EINSTEIN-PE Anticoagulant Trial in Healthcare Claims Data
Brigham and Women's Hospital
NCT04879407
Using a Real-Time Risk Prediction Model to Predict Pediatric Venous Thromboembolism (VTE) Events
Vanderbilt University Medical Center
NCT04574895
Global Anticoagulant Registry in the FIELD- Venous Thromboembolic Events
Thrombosis Research Institute
NCT02155491
Epidemiology of Venous Thromboembolism
Brigham and Women's Hospital
NCT00456196
Prospective Investigation of Pulmonary Embolism Diagnosis III
George Washington University
NCT00241826
Comparison of Low and Intermediate Dose Low-molecular-weight Heparin to Prevent Recurrent Venous Thromboembolism in Pregnancy
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT01828697
Short-term Clinical Deterioration After Acute Pulmonary Embolism
Wake Forest University Health Sciences
NCT03915925
D-dimer to Select Patients With First Unprovoked Venous Thromboembolism Who Can Have Anticoagulants Stopped at 3 Months
McMaster University
NCT00720915
Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information
Brigham and Women's Hospital
NCT00401414
Pulmonary Embolism Response to Fragmentation, Embolectomy, & Catheter Thrombolysis: PERFECT
Stanford University
NCT01097928
Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism
Academic and Community Cancer Research United
NCT02585713
Evaluation of Obstructive Sleep Apnea as a Risk Factor for Pulmonary Embolism
Atlantic Health System
NCT00409045
Evaluation of the Accuracy and Precision of the INRatio® Prothrombin Time (PT) Monitoring System With New INRatio Test Strip Designed for Low Sample Volume and Heparin Insensitivity
Abbott RDx Cardiometabolic
NCT01037270
Accuracy of the D-Dimer Assay for the Exclusion of Pulmonary Embolism in a High Risk Oncologic Population
Memorial Sloan Kettering Cancer Center
NCT00615147
A Genomic Approach to Warfarin Dose Prescription in Admixed Caribbean Hispanics
University of Puerto Ri
NCT02345356
Identify Clinical Conditions That Increase Circulating DNA Levels
University of Florida
NCT01815996
Detection of Pulmonary Embolism With CECT
Bracco Diagnostics
NCT00351754
tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden
Thrombolex
NCT04248868
Nitric Oxide to Treat Pulmonary Embolism
Indiana University School of Medicine
NCT01939301
Non-Interruptive Alerts for Improving Use of Clinical Decision Rules
University of Utah
NCT04702308
Once Daily Enoxaparin for Outpatient Treatment of Acute DVT and/or Pulmonary Embolism
Brigham and Women's Hospital
NCT00413374
Home Rehabilitation After Acute Pulmonary Embolism
University of Rochester
NCT05571189
Phase I Trial of Inhaled Nitric Oxide to Treat Acute Pulmonary Embolism
Wake Forest University Health Sciences
NCT00848731
Investigation Into the Therapeutic Dosage of Fondaparinux Sodium, a Medication Used to Prevent Blood Clots in Morbidly Obese Volunteers
University of Pittsburgh
NCT00436787
First - In - Man Study to Assess the Safety and Feasibility of The Bashir™ Endovascular Catheter for the Treatment of Acute Pulmonary Embolism
Thrombolex
NCT03927508
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 2 |
| Phase 3 | 4 |
| Phase 4 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Pulmonary Embolism Trial Landscape
ClinicalTrials.gov lists 49 US studies indexed under Pulmonary Embolism, and 13 of those are currently open to recruitment — roughly 27% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Pulmonary Embolism shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Pulmonary Embolism is led by Brigham and Women's Hospital with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 49 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Pulmonary Embolism?
PlainTrial tracks 49 US clinical trials for Pulmonary Embolism, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Pulmonary Embolism?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.