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NCT06041594 · ClinicalTrials.gov registry record · NA
Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)
A NA study of Pulmonary Embolism, sponsored by Innova Vascular.
- Recruiting
- Registry status
- NA
- Development phase
- 107
- Enrollment target
- 14
- Study locations
NCT06041594: Recruiting NA study of Pulmonary Embolism, sponsored by Innova Vascular.
NCT06041594 is a NA study of Pulmonary Embolism that is actively recruiting participants, run by Innova Vascular. The registered enrollment target is 107 participants, below the 3,056-participant average among 48 other Pulmonary Embolism trials with a reported enrollment target (96% lower). The trial reports 14 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06041594, a NA study of Pulmonary Embolism, is actively recruiting participants, sponsored by Innova Vascular.
- RECRUITING
- Registry status
- NA
- Development phase
- 107 participants
- Enrollment target
- 14
- Study locations
Study Summary
This is a prospective, multi-center, pivotal study to demonstrate the safety and effectiveness of the Laguna Thrombectomy System for the treatment of pulmonary embolism. The Laguna Thrombectomy System is an investigational device which consists of the Laguna Clot Retriever™ System and the Malibu Aspiration Catheter™ System. These devices are manufactured by Innova Vascular, Inc.
Primary Outcome
* Device-related death within 48 (± 8) hours post-procedure * Major bleeding as defined by GUSTO (moderate or severe) within 48 (± 8) hours post-procedure. * The following treatment-related adverse events within 48 (± 8) hours post-procedure: * Cardio-respiratory deterioration, * Pulmonary vascular injury, and/or * Cardiac injury
Conditions Studied
Interventions
- DEVICE Laguna Thrombectomy System
Study Locations (14)
California
- University of California Irvine - Irvine
- Memorial Care Long Beach Medical Center - Long Beach
- Mission Hospital Regional Medical Center - Mission Viejo
- St. Joseph Hospital of Orange - Orange
Other
- Ankara Bilkent City Hospital - Ankara
- Hacettepe University Hospital - Ankara
- Sancaktepe Sehit Prof. Dr. Ilhan Varan Training and Research Hospital - Istanbul
- Dokuz Eylul University Research and Application Hospital - Izmir
Florida
- Manatee Memorial Hospital - Bradenton
- AdventHealth Tampa - Tampa
District of Columbia
- George Washington University - Washington D.C.
Illinois
- Rush University Medical Center - Chicago
New York
- Albany Medical Center - Albany
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 107 participants |
| Start Date | 2024-08-19 |
| Est. Completion | 2026-04 |
| Phase | NA |
What NCT06041594 shows while recruiting
NCT06041594 is an interventional study that assigns participants to a tested intervention. The registered 107 participants enrollment target is mid-sized for trials with a published cap, below the 3,056-participant average among 48 other Pulmonary Embolism trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Pulmonary Embolism appearing as the primary indexed condition, and to 1 intervention - of which Laguna Thrombectomy System is the first listed.
NCT06041594 lists 14 locations in 7 states (California, Other, Florida).
Frequently Asked Questions
What is clinical trial NCT06041594 about?
NCT06041594 is a clinical study titled "Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)". This is a prospective, multi-center, pivotal study to demonstrate the safety and effectiveness of the Laguna Thrombectomy System for the treatment of pulmonary embolism. The Laguna Thrombectomy System is an investigational device which consists of the Laguna Clot Retriever™ System and the Malibu Asp...
What is the current status of trial NCT06041594?
This trial is currently recruiting. It is a NA study. The enrollment target is 107 participants. The study started on 2024-08-19. Estimated completion is 2026-04.
What conditions does trial NCT06041594 study?
This clinical trial studies the following conditions: Pulmonary Embolism.
What interventions are being tested in trial NCT06041594?
The interventions under investigation include: Laguna Thrombectomy System (DEVICE).
Who is sponsoring clinical trial NCT06041594?
This trial is sponsored by Innova Vascular, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06041594 being conducted?
This trial has 14 study locations across California, District of Columbia, Florida, Illinois, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pulmonary Embolism
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06041594's enrollment target sits among peer trials
107 36th of 48 higher than 13 of 48 other Pulmonary Embolism trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pulmonary Embolism trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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