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NCT07250763 · ClinicalTrials.gov registry record · Phase 4
Therapeutic Initial Heparin Dosing for Patients With Clots or Certain Heart Conditions Admitted to the Hospital
A Phase 4 study of Atrial Fibrillation and Pulmonary Embolism, sponsored by Inova Health Care Services.
- Active
- Registry status
- Phase 4
- Development phase
- 145
- Enrollment target
- 1
- Study location
NCT07250763: Active Phase 4 study of Atrial Fibrillation and Pulmonary Embolism, sponsored by Inova Health Care Services.
NCT07250763 is a Phase 4 study of Atrial Fibrillation and Pulmonary Embolism that is active but no longer recruiting, run by Inova Health Care Services. The registered enrollment target is 145 participants, below the 2,996-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07250763, a Phase 4 study of Atrial Fibrillation and Pulmonary Embolism, is active but no longer recruiting, sponsored by Inova Health Care Services.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 145 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial study is to test whether a mathematical calculation, using the patient's gender, weight and kidney function, can better predict a patient's heparin goal dose than a flat number of units per patient weight can. Participants will have the first dose of heparin infusion calculated, after which if adjustments are needed, the Hospital's prebuilt table for results driven dosing for this purpose is used. The researchers will compare the time it takes for the participants to get to the desired goal using the patient's information for calculation versus patients in the past who received the medication using the flat rate. The hypothesis is that the patients with enhanced personal data, gender, weight and kidney function, included for the initial dose, will get to their goal lab value sooner and with less chance of delay or overshooting the goal. A quicker time to goal lab value is beneficial to patients in many ways, including earlier treatment of the clot or coronary issue that the patient is experiencing.
Primary Outcome
The proportion of patients who have a heparin infusion charted as administered for at least 6 hours who achieve at least one steady state anti-Xa level in the goal range. A steady state anti-Xa level is defined as an anti-Xa level drawn a minimum of 6 hours since the last titration or bolus dose was charted as administered. The goal anti-Xa range is defined as 0.3 to 0.7 for the moderate-intensity protocol and 0.3 to 0.5 for the low-intensity protocol.
Conditions Studied
Interventions
- DRUG Initial Heparin Dose Modification
Study Locations (1)
Virginia
- Inova Alexandria Hospital - Alexandria
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 145 participants |
| Start Date | 2023-09-20 |
| Est. Completion | 2027-05-31 |
| Phase | Phase 4 |
What the registry record for NCT07250763 still lists
NCT07250763 is an interventional study that assigns participants to a tested intervention. The registered 145 participants enrollment target is mid-sized for trials with a published cap, below the 2,996-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (95% lower).
The record links to 5 conditions, with Atrial Fibrillation appearing as the primary indexed condition, and to 1 intervention - of which Initial Heparin Dose Modification is the first listed.
NCT07250763 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT07250763 about?
NCT07250763 is a clinical study titled "Therapeutic Initial Heparin Dosing for Patients With Clots or Certain Heart Conditions Admitted to the Hospital". The goal of this clinical trial study is to test whether a mathematical calculation, using the patient's gender, weight and kidney function, can better predict a patient's heparin goal dose than a flat number of units per patient weight can. Participants will have the first dose of heparin infusion ...
What is the current status of trial NCT07250763?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 145 participants. The study started on 2023-09-20. Estimated completion is 2027-05-31.
What conditions does trial NCT07250763 study?
This clinical trial studies the following conditions: Atrial Fibrillation, Pulmonary Embolism, Deep Vein Thrombosis, Acute Cardiac Syndrome, Mechanical Heart Valve Recipients.
What interventions are being tested in trial NCT07250763?
The interventions under investigation include: Initial Heparin Dose Modification (DRUG).
Who is sponsoring clinical trial NCT07250763?
This trial is sponsored by Inova Health Care Services, which has 75 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07250763 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07250763's enrollment target sits among peer trials
145 123rd of 202 higher than 80 of 202 other Atrial Fibrillation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Atrial Fibrillation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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