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NCT05891886 · ClinicalTrials.gov registry record · Early Phase 1
Supplemental Oxygen in Pulmonary Embolism (SO-PE)
A Early Phase 1 study of Pulmonary Embolism and Venous Thromboembolism, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT05891886 is a Early Phase 1 study of Pulmonary Embolism and Venous Thromboembolism that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 80 participants, below the 3,057-participant average among 48 other Pulmonary Embolism trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05891886, a Early Phase 1 study of Pulmonary Embolism and Venous Thromboembolism, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
A study of how supplemental oxygen helps patients with acute pulmonary embolism (PE). Hypothesis: Oxygen affects right ventricular dysfunction (RVD) in patients with acute pulmonary embolism (PE) primarily by relieving hypoxic pulmonary vasoconstriction and reducing pulmonary pressure (PA) pressure, and that this process is metabolically driven.
Conditions Studied
Interventions
- DRUG Oxygen Therapy
- DEVICE Non-rebreather mask
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2023-10-01 |
| Est. Completion | 2027-06-30 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05891886
The ClinicalTrials.gov registry entry for NCT05891886 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,057-participant average among 48 other Pulmonary Embolism trials with a reported enrollment target (97% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Pulmonary Embolism appearing as the primary indexed condition, and to 2 interventions - of which Oxygen Therapy is the first listed.
NCT05891886 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05891886 about?
NCT05891886 is a clinical study titled "Supplemental Oxygen in Pulmonary Embolism (SO-PE)". A study of how supplemental oxygen helps patients with acute pulmonary embolism (PE). Hypothesis: Oxygen affects right ventricular dysfunction (RVD) in patients with acute pulmonary embolism (PE) primarily by relieving hypoxic pulmonary vasoconstriction and reducing pulmonary pressure (PA) pressure...
What is the current status of trial NCT05891886?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 80 participants. The study started on 2023-10-01. Estimated completion is 2027-06-30.
What conditions does trial NCT05891886 study?
This clinical trial studies the following conditions: Pulmonary Embolism, Venous Thromboembolism, Metabolomics, Oxygen Inhalation Therapy.
What interventions are being tested in trial NCT05891886?
The interventions under investigation include: Oxygen Therapy (DRUG), Non-rebreather mask (DEVICE).
Who is sponsoring clinical trial NCT05891886?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05891886 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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