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NCT05891886 · ClinicalTrials.gov registry record · Early Phase 1
Supplemental Oxygen in Pulmonary Embolism (SO-PE)
A Early Phase 1 study of Pulmonary Embolism and Venous Thromboembolism, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT05891886: Recruiting Early Phase 1 study of Pulmonary Embolism and Venous Thromboembolism, sponsored by Massachusetts General Hospital.
NCT05891886 is a Early Phase 1 study of Pulmonary Embolism and Venous Thromboembolism that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 80 participants, below the 3,057-participant average among 48 other Pulmonary Embolism trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05891886, a Early Phase 1 study of Pulmonary Embolism and Venous Thromboembolism, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
A study of how supplemental oxygen helps patients with acute pulmonary embolism (PE). Hypothesis: Oxygen affects right ventricular dysfunction (RVD) in patients with acute pulmonary embolism (PE) primarily by relieving hypoxic pulmonary vasoconstriction and reducing pulmonary pressure (PA) pressure, and that this process is metabolically driven.
Primary Outcome
PASP is measured on bedside echocardiogram
Conditions Studied
Interventions
- DRUG Oxygen Therapy
- DEVICE Non-rebreather mask
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2023-10-01 |
| Est. Completion | 2027-06-30 |
| Phase | Early Phase 1 |
What NCT05891886 shows while recruiting
NCT05891886 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 3,057-participant average among 48 other Pulmonary Embolism trials with a reported enrollment target (97% lower).
The record links to 4 conditions, with Pulmonary Embolism appearing as the primary indexed condition, and to 2 interventions - of which Oxygen Therapy is the first listed.
NCT05891886 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05891886 about?
NCT05891886 is a clinical study titled "Supplemental Oxygen in Pulmonary Embolism (SO-PE)". A study of how supplemental oxygen helps patients with acute pulmonary embolism (PE). Hypothesis: Oxygen affects right ventricular dysfunction (RVD) in patients with acute pulmonary embolism (PE) primarily by relieving hypoxic pulmonary vasoconstriction and reducing pulmonary pressure (PA) pressure...
What is the current status of trial NCT05891886?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 80 participants. The study started on 2023-10-01. Estimated completion is 2027-06-30.
What conditions does trial NCT05891886 study?
This clinical trial studies the following conditions: Pulmonary Embolism, Venous Thromboembolism, Metabolomics, Oxygen Inhalation Therapy.
What interventions are being tested in trial NCT05891886?
The interventions under investigation include: Oxygen Therapy (DRUG), Non-rebreather mask (DEVICE).
Who is sponsoring clinical trial NCT05891886?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05891886 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05891886's enrollment target sits among peer trials
80 38th of 48 higher than 11 of 48 other Pulmonary Embolism trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pulmonary Embolism trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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