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ClinicalTrials.gov 22 recruiting now later-stage tilt

Psoriatic Arthritis: later-stage trial registry

22 of 49 indexed Psoriatic Arthritis trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #281 of 28,707 conditions by registered trial count.

49 US clinical trials · 22 currently recruiting · #281 of 28,707 conditions by registered trial count

Psoriatic Arthritis: 49 US clinical trials tracked, 22 recruiting.

Psoriatic Arthritis is the subject of 49 registered US clinical trials on ClinicalTrials.gov, 22 of them currently open to new participants. 19 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is UCB Biopharma SRL, running 5 of these trials.

Enrollment posture brief

Registry condition psoriatic-arthritis

OPEN 22 | RECR 45% | LATE 19 | EARLY 8 | RANK #281 | SPON 5

Nearest open-share peer: Cancer (45% recruiting · 621 trials)

Diet, Healthy49%Psoriatic Arthritis (this)45%Duchenne Muscular Dystrophy44.9%Chronic Disease36.7%Arthritis30.6%
Open-enrollment share among volume-matched conditions near Psoriatic Arthritis

Psoriatic Arthritis lists 22 open slots (45% of 49 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Psoriatic Arthritis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Psoriatic Arthritis is recruiting above its size-band peers.

    22 of 49 indexed trials (44.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Psoriatic Arthritis trials is spread across many organizations.

    UCB Biopharma SRL accounts for 5 of 49 trials (10.2%). 28 distinct sponsors appear on at least one study for this condition label.

  3. Typical Psoriatic Arthritis enrolment sits around 250 participants.

    Median target enrolment is 250 among the 49 trials that report a genuine target (sentinel values excluded). 11 of those (22.4%) plan for fewer than 100 participants.

  4. Psoriatic Arthritis research is mostly interventional.

    36 interventional and 13 observational studies make up this index (73.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 24Phase 316Phase 43

Open and recent trials

49 total, page 1 of 1

RECRUITING NA 18,000 participants

Psoriatic Arthritis D2P Screening

Jessica Walsh

NCT04110522

RECRUITING 5,000 participants

Rheumatology Patient Registry and Biorepository

Yale University

NCT04402086

RECRUITING Phase 3 1,182 participants

Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis

Takeda

NCT07286058

RECRUITING Phase 3 1,088 participants

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines

Takeda

NCT06671483

RECRUITING 1,000 participants

Psorcast Mobile Study

Sage Bionetworks

NCT05621369

RECRUITING Phase 3 600 participants

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

Takeda

NCT06671496

RECRUITING NA 520 participants

Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

University of Pennsylvania

NCT05908240

RECRUITING 500 participants

Rheumatology Diet Study

University of Central Florida

NCT06339957

RECRUITING Phase 1 392 participants

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

UCB Biopharma SRL

NCT07290036

RECRUITING Phase 1 300 participants

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

National Cancer Institute (NCI)

NCT03816345

RECRUITING Phase 2 285 participants

A Study of SPY072 in Rheumatic Disease

Spyre Therapeutics

NCT07148414

RECRUITING 200 participants

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

University of California, San Diego

NCT02103361

RECRUITING NA 200 participants

Creating Health Course Study for People With Rheumatological Conditions

Terry L. Wahls

NCT07180537

RECRUITING Phase 4 200 participants

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

Eli Lilly and Company

NCT06864026

RECRUITING 125 participants

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

M.D. Anderson Cancer Center

NCT04751396

RECRUITING Phase 2 120 participants

Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

AbbVie

NCT06865105

RECRUITING 100 participants

Stronger Together Psoriatic Arthritis Wellness Study

Global Healthy Living Foundation

NCT05652608

RECRUITING Phase 4 100 participants

A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

Care Arthritis

NCT06454188

RECRUITING Phase 3 90 participants

A Study to Evaluate the Effect of Bimekizumab on Gene Expression Biomarkers in Study Participants With Moderate to Severe Plaque Psoriasis

UCB Biopharma SRL

NCT06506916

RECRUITING Phase 3 63 participants

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients

University of Pennsylvania

NCT05669833

RECRUITING Phase 1 20 participants

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

UCB Biopharma SRL

NCT06888193

RECRUITING NA 20 participants

Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy

University of California, San Diego

NCT06586281

ACTIVE NOT RECRUITING Phase 3 1,131 participants

A Study to Assess the Long-term Safety, Tolerability, and Efficacy of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis

UCB Biopharma SRL

NCT04009499

ACTIVE NOT RECRUITING Phase 3 964 participants

A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or Intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy

AbbVie

NCT03675308

ACTIVE NOT RECRUITING 925 participants

OTIS Cimzia Pregnancy Registry

University of California, San Diego

NCT01797224

ACTIVE NOT RECRUITING Phase 3 729 participants

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment

Bristol-Myers Squibb

NCT04908189

ACTIVE NOT RECRUITING Phase 3 684 participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

UCB Biopharma SRL

NCT06624228

ACTIVE NOT RECRUITING Phase 3 670 participants

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs

Bristol-Myers Squibb

NCT04908202

ACTIVE NOT RECRUITING Phase 3 529 participants

Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis

Sun Pharmaceutical Industries Limited

NCT04991116

ACTIVE NOT RECRUITING Phase 3 279 participants

Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight

Eli Lilly and Company

NCT06588296

ACTIVE NOT RECRUITING NA 278 participants

Improving Virtual Care of Arthritis: Integrating a Smartphone App Into the EHR for Improved Timeliness of Visits

Brigham and Women's Hospital

NCT06004700

ACTIVE NOT RECRUITING 233 participants

Apremilast Pregnancy Exposure Registry

University of California, San Diego

NCT02775500

ACTIVE NOT RECRUITING NA 135 participants

Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System

Zimmer Biomet

NCT03626038

ACTIVE NOT RECRUITING NA 101 participants

Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity

Brigham and Women's Hospital

NCT05715463

ACTIVE NOT RECRUITING NA 60 participants

Role of Intermittent Fasting in Psoriasis and Psoriatic Arthritis

Ohio State University

NCT05590247

COMPLETED Phase 3 1,705 participants

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD)

AbbVie

NCT03104400

COMPLETED Phase 3 606 participants

Efficacy at 24 Weeks and Long Term Safety, Tolerability and Efficacy up to 2 Years of Secukinumab (AIN457) in Patients With Active Psoriatic Arthritis (PsA)

Novartis Pharmaceuticals

NCT01392326

COMPLETED 466 participants

Remission and Flare in Psoriatic Arthritis: a Prospective 6-month Study With a Double Perspective.

Groupe Hospitalier Pitie-Salpetriere

NCT03119805

COMPLETED Phase 3 394 participants

A Long-Term Efficacy and Safety Study of Ixekizumab (LY2439821) in Participants With Active Psoriatic Arthritis

Eli Lilly and Company

NCT02584855

COMPLETED Phase 3 250 participants

Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis

Amgen

NCT01690299

COMPLETED 171 participants

Psoriatic Arthritis Research Collaborative: Biologic Sub-Study

University of Pennsylvania

NCT03378336

COMPLETED 141 participants

A Study to Learn About the Study Medicine (Called Tofacitinib) in People With Psoriatic Arthritis

Pfizer

NCT05195814

COMPLETED Phase 2 134 participants

Impact of Literacy Level on Patient Education and Health Among People With Arthritis

Brigham and Women's Hospital

NCT00023205

COMPLETED NA 90 participants

Diet Interventions in Psoriatic Arthritis

University of Pennsylvania

NCT04180904

COMPLETED 68 participants

DC-STAMP & TRAF3: Regulators of Osteoclastogenesis and Biomarkers in PsA

University of Rochester

NCT02413749

COMPLETED Phase 4 31 participants

Centocor Microarray Study of Patients

University of Rochester

NCT00462072

COMPLETED 22 participants

National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker Study

University of Rochester

NCT01123265

COMPLETED Phase 2 20 participants

A Phase II Study Evaluating the Efficacy and Safety of AbGn-168H in Patients With Active Psoriatic Arthritis

AbGenomics B.V Taiwan Branch

NCT02267642

COMPLETED Phase 1 17 participants

A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers

UCB Biosciences

NCT02154425

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 4
Phase 3 16
Phase 4 3

Named interventions

Most-linked intervention names on Psoriatic Arthritis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
6 trials
Zasocitinib Drug
3 trials
Bimekizumab Drug
3 trials
Guselkumab Drug
3 trials
Ixekizumab Drug
2 trials
Apremilast Drug
2 trials
Deucravacitinib Drug
2 trials
Risankizumab Drug
2 trials

US sites by state

Facility locations filed on Psoriatic Arthritis trials. A trial with sites in several states counts in each.

California 27 trials
Florida 19 trials
Arizona 15 trials
Pennsylvania 13 trials
New York 13 trials
Texas 11 trials
Michigan 9 trials
Maryland 9 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Psoriatic Arthritis page

49 registered trials, 22 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 22 Psoriatic Arthritis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • UCB Biopharma SRL sponsors the most Psoriatic Arthritis trials on record, review their full trial history before evaluating a specific study. See UCB Biopharma SRL's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Psoriatic Arthritis condition card totals 49 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.