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Psoriatic Arthritis clinical trials
Every US clinical trial registered for Psoriatic Arthritis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
49 US clinical trials · 22 currently recruiting
The research picture
Psoriatic Arthritis has 49 registered US clinical trials, 22 of them open to new participants right now — about 45% of the total.
- 22
- recruiting participants now
- 45%
- of trials open to enrollment
- 19
- in Phase 3–4 (later-stage)
- 5
- top sponsor: UCB Biopharma SRL
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Psoriatic Arthritis D2P Screening
Jessica Walsh
NCT04110522
Rheumatology Patient Registry and Biorepository
Yale University
NCT04402086
Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis
Takeda
NCT07286058
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
Takeda
NCT06671483
Psorcast Mobile Study
Sage Bionetworks
NCT05621369
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines
Takeda
NCT06671496
Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis
University of Pennsylvania
NCT05908240
Rheumatology Diet Study
University of Central Florida
NCT06339957
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
UCB Biopharma SRL
NCT07290036
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
National Cancer Institute (NCI)
NCT03816345
A Study of SPY072 in Rheumatic Disease
Spyre Therapeutics
NCT07148414
Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project
University of California, San Diego
NCT02103361
Creating Health Course Study for People With Rheumatological Conditions
Terry L. Wahls
NCT07180537
A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)
Eli Lilly and Company
NCT06864026
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
M.D. Anderson Cancer Center
NCT04751396
Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis
AbbVie
NCT06865105
Stronger Together Psoriatic Arthritis Wellness Study
Global Healthy Living Foundation
NCT05652608
A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis
CARE ARTHRITIS
NCT06454188
A Study to Evaluate the Effect of Bimekizumab on Gene Expression Biomarkers in Study Participants With Moderate to Severe Plaque Psoriasis
UCB Biopharma SRL
NCT06506916
Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients
University of Pennsylvania
NCT05669833
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
UCB Biopharma SRL
NCT06888193
Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy
University of California, San Diego
NCT06586281
A Study to Assess the Long-term Safety, Tolerability, and Efficacy of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis
UCB Biopharma SRL
NCT04009499
A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or Intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy
AbbVie
NCT03675308
OTIS Cimzia Pregnancy Registry
University of California, San Diego
NCT01797224
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment
Bristol-Myers Squibb
NCT04908189
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis
UCB Biopharma SRL
NCT06624228
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs
Bristol-Myers Squibb
NCT04908202
Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis
Sun Pharmaceutical Industries Limited
NCT04991116
Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight
Eli Lilly and Company
NCT06588296
Improving Virtual Care of Arthritis: Integrating a Smartphone App Into the EHR for Improved Timeliness of Visits
Brigham and Women's Hospital
NCT06004700
Apremilast Pregnancy Exposure Registry
University of California, San Diego
NCT02775500
Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System
Zimmer Biomet
NCT03626038
Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity
Brigham and Women's Hospital
NCT05715463
Role of Intermittent Fasting in Psoriasis and Psoriatic Arthritis
Ohio State University
NCT05590247
A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD)
AbbVie
NCT03104400
Efficacy at 24 Weeks and Long Term Safety, Tolerability and Efficacy up to 2 Years of Secukinumab (AIN457) in Patients With Active Psoriatic Arthritis (PsA)
Novartis Pharmaceuticals
NCT01392326
Remission and Flare in Psoriatic Arthritis: a Prospective 6-month Study With a Double Perspective.
Groupe Hospitalier Pitie-Salpetriere
NCT03119805
A Long-Term Efficacy and Safety Study of Ixekizumab (LY2439821) in Participants With Active Psoriatic Arthritis
Eli Lilly and Company
NCT02584855
Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis
Amgen
NCT01690299
Psoriatic Arthritis Research Collaborative: Biologic Sub-Study
University of Pennsylvania
NCT03378336
A Study to Learn About the Study Medicine (Called Tofacitinib) in People With Psoriatic Arthritis
Pfizer
NCT05195814
Impact of Literacy Level on Patient Education and Health Among People With Arthritis
Brigham and Women's Hospital
NCT00023205
Diet Interventions in Psoriatic Arthritis
University of Pennsylvania
NCT04180904
DC-STAMP & TRAF3: Regulators of Osteoclastogenesis and Biomarkers in PsA
University of Rochester
NCT02413749
Centocor Microarray Study of Patients
University of Rochester
NCT00462072
National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker Study
University of Rochester
NCT01123265
A Phase II Study Evaluating the Efficacy and Safety of AbGn-168H in Patients With Active Psoriatic Arthritis
AbGenomics B.V Taiwan Branch
NCT02267642
A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers
UCB BIOSCIENCES
NCT02154425
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 4 |
| Phase 3 | 16 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Psoriatic Arthritis Trial Landscape
ClinicalTrials.gov lists 49 US studies indexed under Psoriatic Arthritis, and 22 of those are currently open to recruitment — roughly 45% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Psoriatic Arthritis shows 19 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Psoriatic Arthritis is led by UCB Biopharma SRL with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 49 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Psoriatic Arthritis?
PlainTrial tracks 49 US clinical trials for Psoriatic Arthritis, of which 22 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Psoriatic Arthritis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.