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NCT06586281 · ClinicalTrials.gov registry record · NA
Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy
A NA study of Psoriatic Arthritis, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06586281 is a NA study of Psoriatic Arthritis that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 20 participants, below the 852-participant average among 48 other Psoriatic Arthritis trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06586281, a NA study of Psoriatic Arthritis, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
While many studies examine Nonalcoholic fatty liver disease (NAFLD), little is known about its progression to high-risk nonalcoholic steatohepatitis (NASH) in PsA patients. Shared disease mechanisms may explain the increased severity in PsA. This study involves two visits from PsA patients with NAFLD and active disease signs (e.g., swollen joint, enthesitis, or psoriatic plaque). It aims to assess the impact of biological therapies on liver disorders, joints, and skin in PsA patients.
Conditions Studied
Interventions
- DRUG Guselkumab
Study Locations (1)
California
- University of California, San Diego - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-06-01 |
| Est. Completion | 2026-12-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06586281
The ClinicalTrials.gov registry entry for NCT06586281 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 852-participant average among 48 other Psoriatic Arthritis trials with a reported enrollment target (98% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Psoriatic Arthritis appearing as the primary indexed condition, and to 1 intervention - of which Guselkumab is the first listed.
NCT06586281 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT06586281 about?
NCT06586281 is a clinical study titled "Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy". While many studies examine Nonalcoholic fatty liver disease (NAFLD), little is known about its progression to high-risk nonalcoholic steatohepatitis (NASH) in PsA patients. Shared disease mechanisms may explain the increased severity in PsA. This study involves two visits from PsA patients with NAFL...
What is the current status of trial NCT06586281?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2025-06-01. Estimated completion is 2026-12-01.
What conditions does trial NCT06586281 study?
This clinical trial studies the following conditions: Psoriatic Arthritis.
What interventions are being tested in trial NCT06586281?
The interventions under investigation include: Guselkumab (DRUG).
Who is sponsoring clinical trial NCT06586281?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06586281 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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