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NCT01690299 · ClinicalTrials.gov registry record · Phase 3

Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis

A Phase 3 study of Psoriasis and Psoriatic Arthritis, sponsored by Amgen.

Completed
Registry status
Phase 3
Development phase
250
Enrollment target
20
Study locations

NCT01690299 is a Phase 3 study of Psoriasis and Psoriatic Arthritis that has completed, run by Amgen. The registered enrollment target is 250 participants, below the 487-participant average among 125 other Psoriasis trials with a reported enrollment target (49% lower). The trial reports 20 study locations across 13 states.

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The verdict

NCT01690299, a Phase 3 study of Psoriasis and Psoriatic Arthritis, has completed, sponsored by Amgen.

COMPLETED
Registry status
Phase 3
Development phase
250 participants
Enrollment target
20
Study locations

Study Summary

This study will test the clinical effectiveness and safety of apremilast compared with placebo as well as etanercept compared with placebo in the same group of patients with moderate to severe plaque psoriasis.

Interventions

  • DRUG Apremilast
  • DRUG Placebo tablet
  • DRUG Etanercept
  • DRUG Placebo injection

Study Locations (20)

Florida

  • Florida Center for Dermatology, PA - Jacksonville
  • Florida Academic Dermatology Center - Miami
  • International Dermatology Research - Miami
  • Renstar Medical Research - Ocala

California

  • Bakersfield Dermatology and Skin Cancer Medical Group - Bakersfield
  • University of California Irvine-Department of Dermatology - Irvine
  • University of California San Diego Medical Center - San Diego

Illinois

  • NorthShore University HealthSystem - Skokie
  • Southern Illinois University School of Medicine - Springfield

New York

  • Forest Hills Dermatology Group - Forest Hills
  • NYU Department of Dermatology - New York

Arizona

  • Arizona Research Center - Phoenix

Colorado

  • Horizons Clinical Research - Denver

District of Columbia

  • George Washington University - Washington D.C.

Georgia

  • Atlanta Dermatology, Vein and Research Center, PC - Alpharetta

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2012-10-01
Est. Completion 2016-04-04
Phase Phase 3

Sponsor

Amgen

558 total trials

What the Registry Record Tells You About NCT01690299

The ClinicalTrials.gov registry entry for NCT01690299 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 487-participant average among 125 other Psoriasis trials with a reported enrollment target (49% lower). The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Psoriasis appearing as the primary indexed condition, and to 4 interventions - of which Apremilast is the first listed.

NCT01690299 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Florida, California, Illinois.

Frequently Asked Questions

What is clinical trial NCT01690299 about?

NCT01690299 is a clinical study titled "Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis". This study will test the clinical effectiveness and safety of apremilast compared with placebo as well as etanercept compared with placebo in the same group of patients with moderate to severe plaque psoriasis.

What is the current status of trial NCT01690299?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 250 participants. The study started on 2012-10-01. Estimated completion is 2016-04-04.

What conditions does trial NCT01690299 study?

This clinical trial studies the following conditions: Psoriasis, Psoriatic Arthritis.

What interventions are being tested in trial NCT01690299?

The interventions under investigation include: Apremilast (DRUG), Placebo tablet (DRUG), Etanercept (DRUG), Placebo injection (DRUG).

Who is sponsoring clinical trial NCT01690299?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01690299 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.