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ClinicalTrials.gov 26 recruiting now full pipeline #93 of 28,707 conditions

Psoriasis: full-pipeline trial registry

26 of 127 indexed Psoriasis trials are currently recruiting.

Corpus placement: #93 of 28,707 conditions by registered trial count.

127 US clinical trials · 26 currently recruiting · #93 of 28,707 conditions by registered trial count

Psoriasis: 127 US clinical trials tracked, 26 recruiting.

Psoriasis is the subject of 127 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 50 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Bristol-Myers Squibb, running 8 of these trials.

Enrollment posture brief

Registry condition psoriasis

OPEN 26 | RECR 20% | LATE 50 | EARLY 36 | RANK #93 | SPON 8

Nearest open-share peer: Healthy (21% recruiting · 1,096 trials)

Head and Neck Squamous Cell 56.8%Sarcoma45%Solid Tumors33.9%Smoking21.8%Psoriasis (this)20%
Open-enrollment share among volume-matched conditions near Psoriasis

Psoriasis lists 26 open slots (20% of 127 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Psoriasis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Psoriasis is recruiting below its size-band peers.

    26 of 127 indexed trials (20.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Psoriasis trials is spread across many organizations.

    Bristol-Myers Squibb accounts for 8 of 127 trials (6.3%). 65 distinct sponsors appear on at least one study for this condition label.

  3. Typical Psoriasis enrolment sits around 84 participants.

    Median target enrolment is 84 among the 126 trials that report a genuine target (sentinel values excluded). 68 of those (54%) plan for fewer than 100 participants.

  4. Psoriasis research is mostly interventional.

    101 interventional and 26 observational studies make up this index (79.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 120Phase 216Phase 326Phase 424

Open and recent trials

127 total, page 3 of 3

COMPLETED Phase 1 33 participants

A Study to Investigate the Safety, Tolerability, Pharmacokinetic, and Efficacy of ABY-035/AFO2

Affibody

NCT03580278

COMPLETED Phase 1 32 participants

A Phase 1 Study to Assess Single and Multiple Ascending Doses of PBI-100 Topical Cream

Pyramid Biosciences

NCT05514353

COMPLETED Phase 4 31 participants

A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region

Organon and

NCT05789576

COMPLETED 31 participants

Molecular and Cellular Characterization of Spongiotic Dermatitis

University of California, Davis

NCT00371163

COMPLETED Phase 4 31 participants

Centocor Microarray Study of Patients

University of Rochester

NCT00462072

COMPLETED Phase 3 30 participants

Treatment of Psoriasis Using Acitretin in HIV-Positive Patients

Hoffmann-La Roche

NCT00002143

COMPLETED Phase 2 30 participants

Safety and Pharmacokinetics (PK) of Alefacept in Adolescent Subjects With Moderate to Severe Psoriasis

Astellas Pharma

NCT00808223

COMPLETED NA 30 participants

Open Label Study Etanercept's Maintenance Dose in Obese Patients With Moderate to Severe Plaque Type Psoriasis

University of California, San Francisco

NCT00800982

COMPLETED Phase 1 30 participants

Study to Evaluate the Pharmacokinetics and the Safety of M518101 in Plaque Psoriasis Patients

Maruho North America

NCT01844973

COMPLETED NA 29 participants

Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

National Heart, Lung, and Blood Institute (NHLBI)

NCT04271735

COMPLETED Phase 2 24 participants

Safety Study to Assess the Potential for Adrenal Suppression Following Maximal Use Treatment With DSXS

Sun Pharmaceutical Industries

NCT02933528

COMPLETED Phase 4 24 participants

Evaluating Treatment Resistant Dermatitis TaroIIR

Wake Forest University Health Sciences

NCT03050294

COMPLETED Phase 2 20 participants

Etanercept With Tacrolimus for Psoriasis

University of Medicine and Dentistry of New Jersey

NCT00134394

COMPLETED Phase 1 20 participants

To Study the Effects of CD25 and Low Dose Cyclosporin in the Treatment of Active Psoriasis Vulgaris

Rockefeller University

NCT00050648

COMPLETED Phase 4 19 participants

Study to Evaluate Effect of Pandel Cream 0.1% on HPA Axis in Pediatric and Adult Population

Fougera Pharmaceuticals

NCT01137032

COMPLETED 19 participants

Videocapillaroscopy Assessment During Systemic Agent Therapy in Psoriasis

Northwestern University

NCT02162472

COMPLETED NA 18 participants

Cardiovascular Effects in Psoriasis Patients Treated With Adalimumab.

University of North Carolina, Chapel Hill

NCT01320293

COMPLETED 18 participants

An Observational Study of the Use and Safety of Raptiva During Pregnancy (FOLLOW)

Genentech

NCT00097240

COMPLETED Phase 1 16 participants

Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis

Janssen Research & Development

NCT02397382

COMPLETED Phase 1 16 participants

A Study to Assess the Relative Bioavailability of New Oral Formulations of SRT2104 in Healthy Male Volunteers

Sirtris, a GSK Company

NCT01702493

COMPLETED Phase 4 15 participants

Immunologic Response to Secukinumab in Plaque Psoriasis

University of California, San Francisco

NCT02592018

COMPLETED Phase 3 12 participants

A Study of the Early Activity of Ixekizumab (LY2439821) in Moderate-to-Severe Psoriasis

Eli Lilly and Company

NCT02387801

COMPLETED Phase 1 12 participants

Evaluate Whether Combination Therapy With Methotrexate and Raptiva in Psoriasis Patients is Safe and Increases Efficacy

University of California, Davis

NCT00368654

COMPLETED 9 participants

Pilot Studies Testing Levels of P63 in Psoriasis Skin Lesions

Wright State University

NCT04560647

COMPLETED Early Phase 1 8 participants

Safety and Pharmacokinetics of Sustained-release Depot Tacrolimus: A First-in-human Study

Auritec Pharmaceuticals

NCT03626714

COMPLETED Phase 4 6 participants

Can We Miss Pigmented Lesions in Psoriasis Patients?

University of Alabama at Birmingham

NCT01053819

COMPLETED NA

A Study of Retrovir in the Treatment of Psoriasis in HIV-Positive Patients

Glaxo Wellcome

NCT00002286

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Phase Distribution

PhaseTrial count
Phase 1 20
Phase 2 16
Phase 3 26
Phase 4 24

Named interventions

Most-linked intervention names on Psoriasis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
13 trials
Ustekinumab Drug
7 trials
Apremilast Drug
6 trials
Placebo Other
6 trials
Guselkumab Drug
5 trials
Risankizumab Drug
4 trials
M518101 Drug
3 trials
Vehicle Drug
3 trials

US sites by state

Facility locations filed on Psoriasis trials. A trial with sites in several states counts in each.

California 63 trials
Florida 40 trials
New York 31 trials
Illinois 26 trials
Texas 25 trials
Indiana 25 trials
Georgia 22 trials
North Carolina 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Psoriasis page

127 registered trials, 26 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Psoriasis condition card totals 127 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.