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Psoriasis clinical trials
26 of 127 indexed Psoriasis trials are currently recruiting.
127 US clinical trials · 26 currently recruiting
Psoriasis is the subject of 127 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 50 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Bristol-Myers Squibb, running 8 of these trials.
The research picture
Psoriasis has 127 registered US clinical trials, 26 of them open to new participants right now, about 20% of the total.
- 26
- recruiting participants now
- 20%
- of trials open to enrollment
- 50
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Bristol-Myers Squibb
Active & Recent Trials
127 total, page 3 of 3
A Study to Investigate the Safety, Tolerability, Pharmacokinetic, and Efficacy of ABY-035/AFO2
Affibody
NCT03580278
A Phase 1 Study to Assess Single and Multiple Ascending Doses of PBI-100 Topical Cream
Pyramid Biosciences
NCT05514353
A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region
Organon and
NCT05789576
Molecular and Cellular Characterization of Spongiotic Dermatitis
University of California, Davis
NCT00371163
Centocor Microarray Study of Patients
University of Rochester
NCT00462072
Treatment of Psoriasis Using Acitretin in HIV-Positive Patients
Hoffmann-La Roche
NCT00002143
Safety and Pharmacokinetics (PK) of Alefacept in Adolescent Subjects With Moderate to Severe Psoriasis
Astellas Pharma
NCT00808223
Open Label Study Etanercept's Maintenance Dose in Obese Patients With Moderate to Severe Plaque Type Psoriasis
University of California, San Francisco
NCT00800982
Study to Evaluate the Pharmacokinetics and the Safety of M518101 in Plaque Psoriasis Patients
Maruho North America
NCT01844973
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis
National Heart, Lung, and Blood Institute (NHLBI)
NCT04271735
Safety Study to Assess the Potential for Adrenal Suppression Following Maximal Use Treatment With DSXS
Sun Pharmaceutical Industries
NCT02933528
Evaluating Treatment Resistant Dermatitis TaroIIR
Wake Forest University Health Sciences
NCT03050294
Etanercept With Tacrolimus for Psoriasis
University of Medicine and Dentistry of New Jersey
NCT00134394
To Study the Effects of CD25 and Low Dose Cyclosporin in the Treatment of Active Psoriasis Vulgaris
Rockefeller University
NCT00050648
Study to Evaluate Effect of Pandel Cream 0.1% on HPA Axis in Pediatric and Adult Population
Fougera Pharmaceuticals
NCT01137032
Videocapillaroscopy Assessment During Systemic Agent Therapy in Psoriasis
Northwestern University
NCT02162472
Cardiovascular Effects in Psoriasis Patients Treated With Adalimumab.
University of North Carolina, Chapel Hill
NCT01320293
An Observational Study of the Use and Safety of Raptiva During Pregnancy (FOLLOW)
Genentech
NCT00097240
Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis
Janssen Research & Development
NCT02397382
A Study to Assess the Relative Bioavailability of New Oral Formulations of SRT2104 in Healthy Male Volunteers
Sirtris, a GSK Company
NCT01702493
Immunologic Response to Secukinumab in Plaque Psoriasis
University of California, San Francisco
NCT02592018
A Study of the Early Activity of Ixekizumab (LY2439821) in Moderate-to-Severe Psoriasis
Eli Lilly and Company
NCT02387801
Evaluate Whether Combination Therapy With Methotrexate and Raptiva in Psoriasis Patients is Safe and Increases Efficacy
University of California, Davis
NCT00368654
Pilot Studies Testing Levels of P63 in Psoriasis Skin Lesions
Wright State University
NCT04560647
Safety and Pharmacokinetics of Sustained-release Depot Tacrolimus: A First-in-human Study
Auritec Pharmaceuticals
NCT03626714
Can We Miss Pigmented Lesions in Psoriasis Patients?
University of Alabama at Birmingham
NCT01053819
A Study of Retrovir in the Treatment of Psoriasis in HIV-Positive Patients
Glaxo Wellcome
NCT00002286
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 20 |
| Phase 2 | 16 |
| Phase 3 | 26 |
| Phase 4 | 24 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Psoriasis Trial Landscape
127 indexed Psoriasis studies · 26 recruiting (20%).
Phase mix: 50 late (III/IV) vs 36 early (I/II).
Top sponsor: Bristol-Myers Squibb (8 trials), 9 others listed. 27 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Psoriasis?
PlainTrial tracks 127 US clinical trials for Psoriasis, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Psoriasis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.