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ClinicalTrials.gov 26 recruiting now official registry

Psoriasis clinical trials

26 of 127 indexed Psoriasis trials are currently recruiting.

127 US clinical trials · 26 currently recruiting

Psoriasis is the subject of 127 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 50 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Bristol-Myers Squibb, running 8 of these trials.

The research picture

Psoriasis has 127 registered US clinical trials, 26 of them open to new participants right now, about 20% of the total.

26
recruiting participants now
20%
of trials open to enrollment
50
in Phase 3–4 (later-stage)
8
top sponsor: Bristol-Myers Squibb
Phase 120Phase 216Phase 326Phase 424

Active & Recent Trials

127 total, page 3 of 3

COMPLETED Phase 1 33 participants

A Study to Investigate the Safety, Tolerability, Pharmacokinetic, and Efficacy of ABY-035/AFO2

Affibody

NCT03580278

COMPLETED Phase 1 32 participants

A Phase 1 Study to Assess Single and Multiple Ascending Doses of PBI-100 Topical Cream

Pyramid Biosciences

NCT05514353

COMPLETED Phase 4 31 participants

A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region

Organon and

NCT05789576

COMPLETED 31 participants

Molecular and Cellular Characterization of Spongiotic Dermatitis

University of California, Davis

NCT00371163

COMPLETED Phase 4 31 participants

Centocor Microarray Study of Patients

University of Rochester

NCT00462072

COMPLETED Phase 3 30 participants

Treatment of Psoriasis Using Acitretin in HIV-Positive Patients

Hoffmann-La Roche

NCT00002143

COMPLETED Phase 2 30 participants

Safety and Pharmacokinetics (PK) of Alefacept in Adolescent Subjects With Moderate to Severe Psoriasis

Astellas Pharma

NCT00808223

COMPLETED NA 30 participants

Open Label Study Etanercept's Maintenance Dose in Obese Patients With Moderate to Severe Plaque Type Psoriasis

University of California, San Francisco

NCT00800982

COMPLETED Phase 1 30 participants

Study to Evaluate the Pharmacokinetics and the Safety of M518101 in Plaque Psoriasis Patients

Maruho North America

NCT01844973

COMPLETED NA 29 participants

Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

National Heart, Lung, and Blood Institute (NHLBI)

NCT04271735

COMPLETED Phase 2 24 participants

Safety Study to Assess the Potential for Adrenal Suppression Following Maximal Use Treatment With DSXS

Sun Pharmaceutical Industries

NCT02933528

COMPLETED Phase 4 24 participants

Evaluating Treatment Resistant Dermatitis TaroIIR

Wake Forest University Health Sciences

NCT03050294

COMPLETED Phase 2 20 participants

Etanercept With Tacrolimus for Psoriasis

University of Medicine and Dentistry of New Jersey

NCT00134394

COMPLETED Phase 1 20 participants

To Study the Effects of CD25 and Low Dose Cyclosporin in the Treatment of Active Psoriasis Vulgaris

Rockefeller University

NCT00050648

COMPLETED Phase 4 19 participants

Study to Evaluate Effect of Pandel Cream 0.1% on HPA Axis in Pediatric and Adult Population

Fougera Pharmaceuticals

NCT01137032

COMPLETED 19 participants

Videocapillaroscopy Assessment During Systemic Agent Therapy in Psoriasis

Northwestern University

NCT02162472

COMPLETED NA 18 participants

Cardiovascular Effects in Psoriasis Patients Treated With Adalimumab.

University of North Carolina, Chapel Hill

NCT01320293

COMPLETED 18 participants

An Observational Study of the Use and Safety of Raptiva During Pregnancy (FOLLOW)

Genentech

NCT00097240

COMPLETED Phase 1 16 participants

Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis

Janssen Research & Development

NCT02397382

COMPLETED Phase 1 16 participants

A Study to Assess the Relative Bioavailability of New Oral Formulations of SRT2104 in Healthy Male Volunteers

Sirtris, a GSK Company

NCT01702493

COMPLETED Phase 4 15 participants

Immunologic Response to Secukinumab in Plaque Psoriasis

University of California, San Francisco

NCT02592018

COMPLETED Phase 3 12 participants

A Study of the Early Activity of Ixekizumab (LY2439821) in Moderate-to-Severe Psoriasis

Eli Lilly and Company

NCT02387801

COMPLETED Phase 1 12 participants

Evaluate Whether Combination Therapy With Methotrexate and Raptiva in Psoriasis Patients is Safe and Increases Efficacy

University of California, Davis

NCT00368654

COMPLETED 9 participants

Pilot Studies Testing Levels of P63 in Psoriasis Skin Lesions

Wright State University

NCT04560647

COMPLETED Early Phase 1 8 participants

Safety and Pharmacokinetics of Sustained-release Depot Tacrolimus: A First-in-human Study

Auritec Pharmaceuticals

NCT03626714

COMPLETED Phase 4 6 participants

Can We Miss Pigmented Lesions in Psoriasis Patients?

University of Alabama at Birmingham

NCT01053819

COMPLETED NA

A Study of Retrovir in the Treatment of Psoriasis in HIV-Positive Patients

Glaxo Wellcome

NCT00002286

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Phase Distribution

PhaseTrial count
Phase 1 20
Phase 2 16
Phase 3 26
Phase 4 24

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Psoriasis Trial Landscape

127 indexed Psoriasis studies · 26 recruiting (20%).

Phase mix: 50 late (III/IV) vs 36 early (I/II).

Top sponsor: Bristol-Myers Squibb (8 trials), 9 others listed. 27 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Psoriasis?

PlainTrial tracks 127 US clinical trials for Psoriasis, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Psoriasis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.