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NCT02413801 · ClinicalTrials.gov registry record

Serum, Cellular and Imaging Markers of Arthritis in Psoriasis Patients

A clinical trial of Psoriasis, sponsored by University of Rochester.

Completed
Registry status
103
Enrollment target
1
Study location

NCT02413801: Completed study of Psoriasis, sponsored by University of Rochester.

NCT02413801 is a study of Psoriasis that has completed, run by University of Rochester. The registered enrollment target is 103 participants, below the 488-participant average among 125 other Psoriasis trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02413801, a study of Psoriasis, has completed, sponsored by University of Rochester.

COMPLETED
Registry status
103 participants
Enrollment target
1
Study location

Study Summary

The events that underlie the conversion from Psoriasis to Psoriatic Arthritis (PsA) are not well understood. This conversion occurs 30% of the time within the first 10 years of psoriasis diagnosis. PsA patients have about a 50% chance of developing joint damage within the first 2 years of disease. A biomarker that identifies subclinical joint inflammation in psoriasis patients would allow for a diagnostic tool to allow for earlier intervention in psoriasis patients and provide a better understanding of the underlying molecular pathogenesis that may lead to development of new therapeutic targets in PsA.

Primary Outcome

To examine if subclinical PsA, as measured by abnormal ultrasound signals, correlate with peripheral blood cellular and serologic biomarkers of inflammation and joint damage. Power Doppler Ultrasound (PDUS) signals in joints and entheses of approximately 125 Ps pts in order to identify at least 35 pts with subclinical PsA (and 25 healthy controls). Investigators will compare both the frequency of DC-STAMP+ cells (CD14+DCSTAMP+ CD4+DC-STAMP+ DC-STAMP+IL-17+) and serum biomarker 14-3-3η levels bet

Conditions Studied

Study Locations (1)

New York

  • University of Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 103 participants
Start Date 2015-03-19
Est. Completion 2023-12
University of Rochester

636 total trials

What the finished NCT02413801 record still lists

NCT02413801 is an observational study that tracks outcomes without assigning an intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap, below the 488-participant average among 125 other Psoriasis trials with a reported enrollment target (79% lower).

The record links to 1 condition, with Psoriasis appearing as the primary indexed condition, and to 0 interventions.

NCT02413801 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT02413801 about?

NCT02413801 is a clinical study titled "Serum, Cellular and Imaging Markers of Arthritis in Psoriasis Patients". The events that underlie the conversion from Psoriasis to Psoriatic Arthritis (PsA) are not well understood. This conversion occurs 30% of the time within the first 10 years of psoriasis diagnosis. PsA patients have about a 50% chance of developing joint damage within the first 2 years of disease. A...

What is the current status of trial NCT02413801?

This trial is currently completed. The enrollment target is 103 participants. The study started on 2015-03-19. Estimated completion is 2023-12.

What conditions does trial NCT02413801 study?

This clinical trial studies the following conditions: Psoriasis.

Who is sponsoring clinical trial NCT02413801?

This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02413801 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Psoriasis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02413801's enrollment target sits among peer trials

103 57th of 125 higher than 69 of 125 other Psoriasis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Psoriasis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02413801, the US trial registry maintained by the National Library of Medicine. NCT02413801 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.