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NCT00566722 · ClinicalTrials.gov registry record · Phase 3
Open Label Study of Adalimumab in Subjects Who Have a Sub-optimal Response to Systemic Therapy or Phototherapy
A Phase 3 study of Psoriasis, sponsored by Abbott.
- Completed
- Registry status
- Phase 3
- Development phase
- 152
- Enrollment target
- 20
- Study locations
NCT00566722: Completed Phase 3 study of Psoriasis, sponsored by Abbott.
NCT00566722 is a Phase 3 study of Psoriasis that has completed, run by Abbott. The registered enrollment target is 152 participants, below the 488-participant average among 125 other Psoriasis trials with a reported enrollment target (69% lower). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00566722, a Phase 3 study of Psoriasis, has completed, sponsored by Abbott.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 152 participants
- Enrollment target
- 20
- Study locations
Study Summary
The objective of this study was to evaluate the safety and efficacy profile of Humira (adalimumab) in patients who had a sub-optimal response to prior systemic therapy. This open-label study was conducted in a patient population of moderate to severe chronic plaque psoriasis patients, which is an approved patient population for adalimumab.
Primary Outcome
The PGA is a 6-point scale used to measure the severity of a patient's disease. Plaque elevation, scaling, and erythema are rated from 0= clear (no plaque elevation; no scaling; erythema=hyperpigmentation, pigmented macules, diffuse faint pink or red coloration) to 5=very severe (plaque elevation=very marked; scaling=very coarse; erythema=very severe \[extreme red coloration, dusky to deep red coloration\]).
Conditions Studied
Interventions
- BIOLOGICAL adalimumab
Study Locations (20)
New York
- New York University School of Medicine - New York
- Mount Sinai School of Medicine - New York
- Montifiore Medical Center - The Bronx
Texas
- Dermatology Treatment & Research Center, PA Research - Dallas
- Baylor Research Institute - Dallas
- Center for Clinical Studies - Houston
Alberta
- Kirk Barber Research - Calgary
- Stratica Medical - Edmonton
Alabama
- Total Skin and Beauty Dermatology Centers - Birmingham
Arkansas
- Dermatology Research of Arkansas - Little Rock
California
- Therapeutics Clinical Research - San Diego
Florida
- Florida Academic Dermatology Centers - Miami
Georgia
- Peachtree Dermatology Associates - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 152 participants |
| Start Date | 2008-01 |
| Est. Completion | 2009-04 |
| Phase | Phase 3 |
What the finished NCT00566722 record still lists
NCT00566722 is an interventional study that assigns participants to a tested intervention. The registered 152 participants enrollment target is mid-sized for trials with a published cap, below the 488-participant average among 125 other Psoriasis trials with a reported enrollment target (69% lower).
The record links to 1 condition, with Psoriasis appearing as the primary indexed condition, and to 1 intervention - of which adalimumab is the first listed.
NCT00566722 names 20 study sites across 15 states, led by New York, Texas, Alberta.
Frequently Asked Questions
What is clinical trial NCT00566722 about?
NCT00566722 is a clinical study titled "Open Label Study of Adalimumab in Subjects Who Have a Sub-optimal Response to Systemic Therapy or Phototherapy". The objective of this study was to evaluate the safety and efficacy profile of Humira (adalimumab) in patients who had a sub-optimal response to prior systemic therapy. This open-label study was conducted in a patient population of moderate to severe chronic plaque psoriasis patients, which is an ap...
What is the current status of trial NCT00566722?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 152 participants. The study started on 2008-01. Estimated completion is 2009-04.
What conditions does trial NCT00566722 study?
This clinical trial studies the following conditions: Psoriasis.
What interventions are being tested in trial NCT00566722?
The interventions under investigation include: adalimumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT00566722?
This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00566722 being conducted?
This trial has 20 study locations across Alabama, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Psoriasis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00566722's enrollment target sits among peer trials
152 46th of 125 higher than 79 of 125 other Psoriasis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Psoriasis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977
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