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COMPLETED Phase 3

Open Label Study of Adalimumab in Subjects Who Have a Sub-optimal Response to Systemic Therapy or Phototherapy

NCT00566722 · View on ClinicalTrials.gov ↗

Study Summary

The objective of this study was to evaluate the safety and efficacy profile of Humira (adalimumab) in patients who had a sub-optimal response to prior systemic therapy. This open-label study was conducted in a patient population of moderate to severe chronic plaque psoriasis patients, which is an approved patient population for adalimumab.

Conditions Studied

Interventions

  • BIOLOGICAL adalimumab

Study Locations (20)

New York

  • New York University School of Medicine — New York
  • Mount Sinai School of Medicine — New York
  • Montifiore Medical Center — The Bronx

Texas

  • Dermatology Treatment & Research Center, PA Research — Dallas
  • Baylor Research Institute — Dallas
  • Center for Clinical Studies — Houston

Alberta

  • Kirk Barber Research — Calgary
  • Stratica Medical — Edmonton

Alabama

  • Total Skin and Beauty Dermatology Centers — Birmingham

Arkansas

  • Dermatology Research of Arkansas — Little Rock

California

  • Therapeutics Clinical Research — San Diego

Florida

  • Florida Academic Dermatology Centers — Miami

Georgia

  • Peachtree Dermatology Associates — Atlanta

Trial Details

FieldValue
Enrollment Target 152 participants
Start Date 2008-01
Est. Completion 2009-04
Phase Phase 3

Sponsor

Abbott

43 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00566722

The ClinicalTrials.gov registry entry for NCT00566722 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 152 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Abbott, which has 43 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Psoriasis appearing as the primary indexed condition, and to 1 intervention — of which adalimumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00566722 reports 20 study locations spanning 15 distinct geographic areas — top geographies include New York, Texas, Alberta. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00566722 about?

NCT00566722 is a clinical study titled "Open Label Study of Adalimumab in Subjects Who Have a Sub-optimal Response to Systemic Therapy or Phototherapy". The objective of this study was to evaluate the safety and efficacy profile of Humira (adalimumab) in patients who had a sub-optimal response to prior systemic therapy. This open-label study was conducted in a patient population of moderate to severe chronic plaque psoriasis patients, which is an ap...

What is the current status of trial NCT00566722?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 152 participants. The study started on 2008-01. Estimated completion is 2009-04.

What conditions does trial NCT00566722 study?

This clinical trial studies the following conditions: Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00566722?

The interventions under investigation include: adalimumab (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00566722?

This trial is sponsored by Abbott, which has 43 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00566722 being conducted?

This trial has 20 study locations across Alabama, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial