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COMPLETED Phase 2

A Study of R3421 in Patients With Moderate to Severe Chronic Plaque Psoriasis.

NCT00504270 · View on ClinicalTrials.gov ↗

Study Summary

This study will investigate the safety, efficacy and pharmacokinetics of R3421 in patients with moderate to severe chronic plaque psoriasis. Patients will be randomized to one of 3 treatment groups to receive once daily oral treatment with a)R3421 20mg, b)R3421 120mg, or c)placebo. The anticipated time on study treatment is \<3 months, and the target sample size is \<100 individuals.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG RG3421 120mg
  • DRUG RG3421 20mg

Study Locations (15)

New York

  • — New York
  • — New York
  • — Stony Brook

Texas

  • — Galveston
  • — San Antonio
  • — Webster

Arkansas

  • — Hot Springs
  • — Little Rock

California

  • — Santa Monica

Georgia

  • — Alpharetta

New Jersey

  • — East Windsor

New Mexico

  • — Albuquerque

North Carolina

  • — Winston-Salem

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2007-07
Est. Completion 2009-09
Phase Phase 2

Sponsor

Hoffmann-La Roche

758 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00504270

The ClinicalTrials.gov registry entry for NCT00504270 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 758 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Psoriasis appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00504270 reports 15 study locations spanning 10 distinct geographic areas — top geographies include New York, Texas, Arkansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00504270 about?

NCT00504270 is a clinical study titled "A Study of R3421 in Patients With Moderate to Severe Chronic Plaque Psoriasis.". This study will investigate the safety, efficacy and pharmacokinetics of R3421 in patients with moderate to severe chronic plaque psoriasis. Patients will be randomized to one of 3 treatment groups to receive once daily oral treatment with a)R3421 20mg, b)R3421 120mg, or c)placebo. The anticipated t...

What is the current status of trial NCT00504270?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 66 participants. The study started on 2007-07. Estimated completion is 2009-09.

What conditions does trial NCT00504270 study?

This clinical trial studies the following conditions: Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00504270?

The interventions under investigation include: Placebo (DRUG), RG3421 120mg (DRUG), RG3421 20mg (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00504270?

This trial is sponsored by Hoffmann-La Roche, which has 758 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00504270 being conducted?

This trial has 15 study locations across Arkansas, California, Georgia, New Jersey, New Mexico. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial