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Risankizumab Versus Secukinumab for Participants With Moderate to Severe Plaque Psoriasis
NCT03478787 · View on ClinicalTrials.gov ↗
Study Summary
The main objective of this study is to evaluate the efficacy and safety of risankizumab compared with secukinumab for the treatment of adult subjects with moderate to severe plaque psoriasis who are candidates for systemic therapy.
Conditions Studied
Interventions
- DRUG risankizumab
- DRUG secukinumab
Study Locations (20)
California
- Bakersfield Derma & Skin Cance /ID# 202115 — Bakersfield
- Center for Dermatology Clin Res /ID# 202116 — Fremont
- Dermatology Res. Assoc., CA /ID# 202170 — Los Angeles
- UC Davis Health /ID# 202263 — Sacramento
- Medderm Associates /ID# 202162 — San Diego
Florida
- Tory P Sullivan, MD PA /ID# 202177 — North Miami Beach
- Renstar Medical Research /ID# 202113 — Ocala
- Progressive Medical Research /ID# 202183 — Port Orange
- Integrated Clinical Research LLC /ID# 202152 — West Palm Beach
Arizona
- Advanced Research Associates - Glendale /ID# 204335 — Glendale
- Alliance Dermatology and MOHs /ID# 204336 — Phoenix
Massachusetts
- ORA, Inc. /ID# 204342 — Andover
- Beth Israel Deaconess Medical Center /ID# 204340 — Boston
Connecticut
- UConn Health Main /ID# 201745 — Farmington
Kentucky
- Dermatology Specialists Resear /ID# 202145 — Louisville
Maryland
- Dermatology and Skin Cancer Specialists, LLC /ID# 203938 — Rockville
Minnesota
- Minnesota Clinical Study Center /ID# 202369 — New Brighton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 327 participants |
| Start Date | 2018-05-08 |
| Est. Completion | 2020-07-08 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03478787
The ClinicalTrials.gov registry entry for NCT03478787 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 327 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AbbVie, which has 603 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Psoriasis appearing as the primary indexed condition, and to 2 interventions — of which risankizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03478787 reports 20 study locations spanning 11 distinct geographic areas — top geographies include California, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03478787 about?
NCT03478787 is a clinical study titled "Risankizumab Versus Secukinumab for Participants With Moderate to Severe Plaque Psoriasis". The main objective of this study is to evaluate the efficacy and safety of risankizumab compared with secukinumab for the treatment of adult subjects with moderate to severe plaque psoriasis who are candidates for systemic therapy.
What is the current status of trial NCT03478787?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 327 participants. The study started on 2018-05-08. Estimated completion is 2020-07-08.
What conditions does trial NCT03478787 study?
This clinical trial studies the following conditions: Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03478787?
The interventions under investigation include: risankizumab (DRUG), secukinumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03478787?
This trial is sponsored by AbbVie, which has 603 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03478787 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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