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NCT00638690 · ClinicalTrials.gov registry record · Phase 3
Abiraterone Acetate in Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
A Phase 3 study of Prostatic Neoplasms, sponsored by Cougar Biotechnology.
- Completed
- Registry status
- Phase 3
- Development phase
- 1,195
- Enrollment target
- 20
- Study locations
NCT00638690: Completed Phase 3 study of Prostatic Neoplasms, sponsored by Cougar Biotechnology.
NCT00638690 is a Phase 3 study of Prostatic Neoplasms that has completed, run by Cougar Biotechnology. The registered enrollment target is 1,195 participants, above the 496-participant average among 65 other Prostatic Neoplasms trials with a reported enrollment target (141% higher). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00638690, a Phase 3 study of Prostatic Neoplasms, has completed, sponsored by Cougar Biotechnology.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 1,195 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a phase 3 study to compare the clinical benefit of abiraterone acetate plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer (CRPC) who have failed one or two chemotherapy regimens. At least one of the previous chemotherapies must have contained docetaxel.
Primary Outcome
Overall survival is defined as the time interval from the date of randomization to the date of death from any cause.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Abiraterone acetate
- DRUG Prednisone/prednisolone
Study Locations (20)
California
- - Beverly Hills
- - Duarte
- - Los Angeles
- - Marina del Rey
- - Sacramento
- - San Diego
- - San Francisco
Florida
- - Boca Raton
- - Fort Lauderdale
- - Fort Myers
- - West Palm Beach
Connecticut
- - Bristol
- - New Haven
- - Stamford
Alabama
- - Birmingham
Arizona
- - Tucson
Colorado
- - Aurora
Georgia
- - Atlanta
Hawaii
- - Honolulu
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,195 participants |
| Start Date | 2008-05 |
| Est. Completion | 2012-10 |
| Phase | Phase 3 |
What the finished NCT00638690 record still lists
NCT00638690 is an interventional study that assigns participants to a tested intervention. Its 1,195 participants enrollment target places it among the larger protocols in the corpus, above the 496-participant average among 65 other Prostatic Neoplasms trials with a reported enrollment target (141% higher).
The record links to 1 condition, with Prostatic Neoplasms appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT00638690 names 20 study sites across 9 states, led by California, Florida, Connecticut.
Frequently Asked Questions
What is clinical trial NCT00638690 about?
NCT00638690 is a clinical study titled "Abiraterone Acetate in Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy". This is a phase 3 study to compare the clinical benefit of abiraterone acetate plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer (CRPC) who have failed one or two chemotherapy regimens. At least one of the previous chemotherapies must have ...
What is the current status of trial NCT00638690?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,195 participants. The study started on 2008-05. Estimated completion is 2012-10.
What conditions does trial NCT00638690 study?
This clinical trial studies the following conditions: Prostatic Neoplasms.
What interventions are being tested in trial NCT00638690?
The interventions under investigation include: Placebo (DRUG), Abiraterone acetate (DRUG), Prednisone/prednisolone (DRUG).
Who is sponsoring clinical trial NCT00638690?
This trial is sponsored by Cougar Biotechnology, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00638690 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Prostatic Neoplasms
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00638690's enrollment target sits among peer trials
1,195 10th of 65 higher than 56 of 65 other Prostatic Neoplasms trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Prostatic Neoplasms trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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