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NCT07319871 · ClinicalTrials.gov registry record · Phase 1

A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

A Phase 1 study of Prostatic Neoplasms, sponsored by Janssen Research & Development.

Recruiting
Registry status
Phase 1
Development phase
40
Enrollment target
3
Study locations

NCT07319871 is a Phase 1 study of Prostatic Neoplasms that is actively recruiting participants, run by Janssen Research & Development. The registered enrollment target is 40 participants, below the 514-participant average among 65 other Prostatic Neoplasms trials with a reported enrollment target (92% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT07319871, a Phase 1 study of Prostatic Neoplasms, is actively recruiting participants, sponsored by Janssen Research & Development.

RECRUITING
Registry status
Phase 1
Development phase
40 participants
Enrollment target
3
Study locations

Study Summary

The purpose of this study is to identify the recommended phase 2 combination dose (RP2CD) of Pasritamig in combination with JNJ-86974680 in Part 1 (Dose finding) of the study and to determine how safe and tolerable the RP2CD is for treatment of participants with advanced prostate cancer in Part 2 (Dose expansion) of study.

Conditions Studied

Prostatic Neoplasms

Interventions

  • DRUG Pasritamig
  • DRUG JNJ-86974680

Study Locations (3)

Florida

  • Florida Cancer Specialists - Sarasota

New York

  • Columbia University Medical Center - New York

Other

  • Royal Marsden Hospital - Sutton

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2026-01-14
Est. Completion 2027-04-30
Phase Phase 1

Sponsor

Janssen Research & Development

593 total trials

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What the Registry Record Tells You About NCT07319871

The ClinicalTrials.gov registry entry for NCT07319871 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 514-participant average among 65 other Prostatic Neoplasms trials with a reported enrollment target (92% lower). The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Prostatic Neoplasms appearing as the primary indexed condition, and to 2 interventions - of which Pasritamig is the first listed.

NCT07319871 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Florida, New York, Other.

Frequently Asked Questions

What is clinical trial NCT07319871 about?

NCT07319871 is a clinical study titled "A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer". The purpose of this study is to identify the recommended phase 2 combination dose (RP2CD) of Pasritamig in combination with JNJ-86974680 in Part 1 (Dose finding) of the study and to determine how safe and tolerable the RP2CD is for treatment of participants with advanced prostate cancer in Part 2 (D...

What is the current status of trial NCT07319871?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2026-01-14. Estimated completion is 2027-04-30.

What conditions does trial NCT07319871 study?

This clinical trial studies the following conditions: Prostatic Neoplasms.

What interventions are being tested in trial NCT07319871?

The interventions under investigation include: Pasritamig (DRUG), JNJ-86974680 (DRUG).

Who is sponsoring clinical trial NCT07319871?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07319871 being conducted?

This trial has 3 study locations across Florida, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.