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NCT02446444 · ClinicalTrials.gov registry record · Phase 3
Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer
A Phase 3 study of Prostatic Neoplasms, sponsored by University of Sydney.
- Active
- Registry status
- Phase 3
- Development phase
- 802
- Enrollment target
- 20
- Study locations
NCT02446444 is a Phase 3 study of Prostatic Neoplasms that is active but no longer recruiting, run by University of Sydney. The registered enrollment target is 802 participants, above the 502-participant average among 65 other Prostatic Neoplasms trials with a reported enrollment target (60% higher). The trial reports 20 study locations across 3 states.
The verdict
NCT02446444, a Phase 3 study of Prostatic Neoplasms, is active but no longer recruiting, sponsored by University of Sydney.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 802 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to determine the effectiveness of enzalutamide as part of adjuvant androgen deprivation therapy (ADT) with a luteinizing hormone releasing hormone analogue (LHRHA) in men having radiation therapy for localised prostate cancer at high risk of recurrence.
Conditions Studied
Interventions
- DRUG Enzalutamide
- DRUG Conventional NSAA
- DRUG LHRHA
- RADIATION External Beam Radiotherapy (78 Gy in 39 fractions or 46 Gy in 23 fractions plus brachytherapy boost)
Study Locations (20)
New South Wales
- Blacktown Hospital - Blacktown
- Campbelltown Hospital - Campbelltown
- Chris O'Brien Lifehouse - Camperdown
- Genesis Cancer Care Newcastle - Gateshead
- Gosford Hospital - Gosford
- St George Hospital - Kogarah
- Liverpool Hospital - Liverpool
- Orange Health Service - Orange
- Prince of Wales Hospital - Randwick
- Royal North Shore Hospital - St Leonards
- St Vincent's Hospital - Sydney
- Tamworth Rural Referral Hospital - Tamworth
- Sydney Adventist Hospital - Wahroonga
- Calvary Mater Newcastle - Waratah
- Westmead Hospital - Westmead
- Wollongong Hospital - Wollongong
Massachusetts
- Dana Farber Cancer Institute - Boston
- Beth Israel Deaconess Medical Center - Boston
Queensland
- Genesis Cancer Care Queensland - Wesley and Chermside - Auchenflower
- Townsville Hospital - Douglas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 802 participants |
| Start Date | 2014-03 |
| Est. Completion | 2026-03 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02446444
The ClinicalTrials.gov registry entry for NCT02446444 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 802 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 502-participant average among 65 other Prostatic Neoplasms trials with a reported enrollment target (60% higher). The listed sponsor is University of Sydney, which has 9 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Prostatic Neoplasms appearing as the primary indexed condition, and to 4 interventions - of which Enzalutamide is the first listed.
NCT02446444 reports 20 study locations spanning 3 distinct geographic areas - top geographies include New South Wales, Massachusetts, Queensland.
Frequently Asked Questions
What is clinical trial NCT02446444 about?
NCT02446444 is a clinical study titled "Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer". The purpose of this study is to determine the effectiveness of enzalutamide as part of adjuvant androgen deprivation therapy (ADT) with a luteinizing hormone releasing hormone analogue (LHRHA) in men having radiation therapy for localised prostate cancer at high risk of recurrence.
What is the current status of trial NCT02446444?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 802 participants. The study started on 2014-03. Estimated completion is 2026-03.
What conditions does trial NCT02446444 study?
This clinical trial studies the following conditions: Prostatic Neoplasms.
What interventions are being tested in trial NCT02446444?
The interventions under investigation include: Enzalutamide (DRUG), Conventional NSAA (DRUG), LHRHA (DRUG), External Beam Radiotherapy (78 Gy in 39 fractions or 46 Gy in 23 fractions plus brachytherapy boost) (RADIATION).
Who is sponsoring clinical trial NCT02446444?
This trial is sponsored by University of Sydney, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02446444 being conducted?
This trial has 20 study locations across Massachusetts, New South Wales, Queensland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.