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ClinicalTrials.gov 275 recruiting now early-phase tilt #4 of 28,963 conditions

Prostate Cancer: early-phase trial registry

275 of 749 indexed Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4 of 28,963 conditions by registered trial count.

749 US clinical trials · 275 currently recruiting · #4 of 28,963 conditions by registered trial count

Prostate Cancer: 749 US clinical trials tracked, 275 recruiting.

Prostate Cancer is the subject of 749 registered US clinical trials on ClinicalTrials.gov, 275 of them currently open to new participants. 75 are in Phase 3-4 (later-stage) and 344 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 53 of these trials.

Open enrollment, early-phase tilt

Prostate Cancer has 749 registered US clinical trials, 275 of them open to new participants right now, about 37% of the total.

275
recruiting participants now
37%
of trials open to enrollment
75
in Phase 3-4 (later-stage)
53
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #4 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Prostate Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostate Cancer recruits in line with its size-band peers.

    275 of 749 indexed trials (36.7%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostate Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 53 of 749 trials (7.1%). 283 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostate Cancer enrolment sits around 82 participants.

    Median target enrolment is 82 among the 736 trials that report a genuine target (sentinel values excluded). 389 of those (52.9%) plan for fewer than 100 participants.

  4. Prostate Cancer research is mostly interventional.

    628 interventional and 121 observational studies make up this index (83.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1156Phase 2188Phase 362Phase 413

Open and recent trials

749 total, page 8 of 15

ACTIVE NOT RECRUITING 135 participants

Multimodal Machine Learning Characterization of Solid Tumors

Ciprian Catana, MD, PhD

NCT04687969

ACTIVE NOT RECRUITING NA 135 participants

Testing Home-based Exercise Strategies in Underserved Minority Cancer Patients Undergoing Chemotherapy: the THRIVE Study

Dana-Farber Cancer Institute

NCT05327452

ACTIVE NOT RECRUITING Phase 2 134 participants

Randomized Phase II Trial of Salvage Radiotherapy for Prostate Cancer In 4 Weeks v. 2 Weeks

Weill Medical College of Cornell University

NCT04422132

ACTIVE NOT RECRUITING Phase 1 125 participants

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

Sapience Therapeutics

NCT04478279

ACTIVE NOT RECRUITING Phase 1 120 participants

Dose Escalation Study Using Ultra-Hypofractionated, Image-Guided, Intensity-Modulated Radiotherapy in Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT00911118

ACTIVE NOT RECRUITING Phase 2 120 participants

Evaluation of Treatment Response Using Multiparametric MRI After Prostate Radiotherapy

Memorial Sloan Kettering Cancer Center

NCT02312401

ACTIVE NOT RECRUITING Phase 2 118 participants

Human Amnion Membrane Allograft and Early Return of Erectile Function After Radical Prostatectomy

University of Miami

NCT05842057

ACTIVE NOT RECRUITING 118 participants

Evaluation of Neuroendocrine Differentiation as a Potential Mechanism of Tumor Recurrence Following Radiotherapy

Mayo Clinic

NCT03017794

ACTIVE NOT RECRUITING Phase 2 115 participants

Clinical Trial of Green Tea Catechins in Men on Active Surveillance

H. Lee Moffitt Cancer Center and Research Institute

NCT04300855

ACTIVE NOT RECRUITING NA 113 participants

Physical Therapy for Men Undergoing Prostatectomy

Indiana University

NCT02558946

ACTIVE NOT RECRUITING Phase 2 111 participants

Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide

Alliance Foundation Trials

NCT04335682

ACTIVE NOT RECRUITING Phase 2 103 participants

Multicohort Phase II Trial of sEphB4-HSA+Pembrolizumab in Solid Tumors

University of Southern California

NCT02717156

ACTIVE NOT RECRUITING Phase 2 102 participants

Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Metastatic Prostatic Adenocarcinoma

Memorial Sloan Kettering Cancer Center

NCT03436654

ACTIVE NOT RECRUITING Phase 1 102 participants

A Multi-Center Trial of Androgen Suppression With Abiraterone Acetate, Leuprolide, PARP Inhibition and Stereotactic Body Radiotherapy in Prostate Cancer

University of Michigan Rogel Cancer Center

NCT04194554

ACTIVE NOT RECRUITING NA 100 participants

Biomarker Monitoring of Prostate Cancer Patients With RSI MRI (ProsRSI)

University of California, San Diego

NCT04349501

ACTIVE NOT RECRUITING NA 100 participants

CyberKnife Dose Escalation Prostate Cancer Trial

Crozer-Keystone Health System

NCT03822494

ACTIVE NOT RECRUITING NA 100 participants

Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer

Hoag Memorial Hospital Presbyterian

NCT03889119

ACTIVE NOT RECRUITING Phase 1 98 participants

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Sensei Biotherapeutics

NCT05864144

ACTIVE NOT RECRUITING Phase 2 96 participants

18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer

National Cancer Institute (NCI)

NCT03173924

ACTIVE NOT RECRUITING NA 95 participants

Predicting Location and Extent of Prostate Cancer Using Micro-Ultrasound Imaging

Stanford University

NCT04981223

ACTIVE NOT RECRUITING Phase 2 91 participants

A Study of MRI-guided High-dose Radiation Therapy in Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT04997018

ACTIVE NOT RECRUITING 88 participants

A Study of Telemedicine Shared Medical Appointments (SMAs) Versus Individual Telemedicine Visits for People With Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT05416996

ACTIVE NOT RECRUITING NA 80 participants

Prostate Cancer Genius App Education and Home-based PSA Screening for African American Men

University of Oklahoma

NCT05331638

ACTIVE NOT RECRUITING NA 80 participants

High-Dose Lymph Node Intensity Modulated Radiation Therapy and Hypofractionated Prostate (SIB)

Medical College of Wisconsin

NCT02177292

ACTIVE NOT RECRUITING NA 76 participants

Whole-Food Plant-Based Diet to Control Weight and MetaboInflammation in Overweight/Obese Men With Prostate Cancer

Weill Medical College of Cornell University

NCT05471414

ACTIVE NOT RECRUITING 75 participants

Analyzing the Composition of Tears and Blood for Discovery of Novel Signatures of Aggressive Prostate Cancer

University of Arkansas

NCT01514669

ACTIVE NOT RECRUITING NA 74 participants

Feasibility of Hormones and Radiation for Intermediate or High Risk Prostate Cancer

University of Chicago

NCT01342367

ACTIVE NOT RECRUITING Phase 1 70 participants

TH1902 in Patients With Advanced Solid Tumors

Theratechnologies

NCT04706962

ACTIVE NOT RECRUITING NA 68 participants

Exercise for Tumor Suppressive Impact in Black Men With Prostate Cancer on Active Surveillance: The REMOVE Trial

Dana-Farber Cancer Institute

NCT05918263

ACTIVE NOT RECRUITING Phase 2 64 participants

Sunitinib Malate With Hormonal Ablation for Patients Who Will Have Prostatectomy

M.D. Anderson Cancer Center

NCT00329043

ACTIVE NOT RECRUITING Phase 2 61 participants

Phase II Study of Pencil Beam Scanning Proton Stereotactic Body Radiation Therapy for Prostate Cancer

The New York Proton Center

NCT04842890

ACTIVE NOT RECRUITING Phase 1 60 participants

Biodistribution and Dosimetry of Ga-68 P16-093 in Prostate Cancer

Five Eleven Pharma

NCT03444844

ACTIVE NOT RECRUITING Phase 1 60 participants

Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC

Weill Medical College of Cornell University

NCT04506567

ACTIVE NOT RECRUITING Phase 1 60 participants

An Acupuncture Study for Prostate Cancer Survivors With Urinary Issues

Memorial Sloan Kettering Cancer Center

NCT05540392

ACTIVE NOT RECRUITING Phase 1 60 participants

Stereotactic Ablative Radiotherapy (SABR) of Pelvis and Prostate Targets For High Risk Prostate Cancer

University of Texas Southwestern Medical Center

NCT02353819

ACTIVE NOT RECRUITING Phase 2 60 participants

pTVG-HP DNA Vaccine With or Without pTVG-AR DNA Vaccine and Pembrolizumab in Patients With Castration-Resistant, Metastatic Prostate Cancer

University of Wisconsin, Madison

NCT04090528

ACTIVE NOT RECRUITING Phase 2 60 participants

Study of TGF-β Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT02452008

ACTIVE NOT RECRUITING Phase 1 59 participants

Nivolumab and BMS-986253 for Hormone-Sensitive Prostate Cancer (MAGIC-8)

Mark Stein

NCT03689699

ACTIVE NOT RECRUITING NA 58 participants

A Multi-modal, Physician-centered Intervention to Improve Guideline-concordant Prostate Cancer Imaging

VA Office of Research and Development

NCT03445559

ACTIVE NOT RECRUITING 58 participants

Prostate-Specific Membrane Antigen (PSMA) PET Scans in People Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT04030338

ACTIVE NOT RECRUITING NA 58 participants

Hispanic Adapted and Culturally Relevant Exercising Together

University of Arizona

NCT06018311

ACTIVE NOT RECRUITING Phase 2 55 participants

177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer

Weill Medical College of Cornell University

NCT00859781

ACTIVE NOT RECRUITING NA 55 participants

Developing Inclusive Support and Intervention for Spanish-speaking Latiné Prostate Cancer Survivors

Case Comprehensive Cancer Center

NCT06435871

ACTIVE NOT RECRUITING NA 54 participants

MRI Guided SBRT for Localized Prostate Cancer

Rush University Medical Center

NCT03778112

ACTIVE NOT RECRUITING Phase 1 54 participants

Combining Ipilimumab With Abiraterone Acetate Plus Prednisone in Chemotherapy and Immunotherapy-naïve Patients With Progressive Metastatic Castration-resistant Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT01688492

ACTIVE NOT RECRUITING NA 53 participants

Clinical Investigation of the da Vinci Surgical System

Intuitive Surgical

NCT05682742

ACTIVE NOT RECRUITING Phase 4 50 participants

Evaluating Fluciclovine PET in Patients With Biochemical Recurrence of Prostate Cancer and a Negative PSMA PET

OHSU Knight Cancer Institute

NCT05722925

ACTIVE NOT RECRUITING Phase 1 50 participants

Evaluation of Xaluritamig in High-Risk, Biochemically Recurrent, Non-metastatic Castrate-sensitive Prostate Cancer

Amgen

NCT06555796

ACTIVE NOT RECRUITING Phase 1 50 participants

Phase I Dose-escalation Study of Fractionated 177Lu-PSMA-617 for Progressive Metastatic CRPC

Weill Medical College of Cornell University

NCT03042468

ACTIVE NOT RECRUITING Phase 2 50 participants

A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT05100472

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Phase Distribution

PhaseTrial count
Phase 1 156
Phase 2 188
Phase 3 62
Phase 4 13

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Prostate Cancer right now

275 recruiting of 749 indexed (37% open).

Phase mix: 75 late (III/IV) vs 344 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (53 trials), 9 others listed. 50 shown below, recruiting first. #4 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Prostate Cancer?

PlainTrial tracks 749 US clinical trials for Prostate Cancer, of which 275 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prostate Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.