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ClinicalTrials.gov 275 recruiting now early-phase tilt #4 of 28,707 conditions

Prostate Cancer: early-phase trial registry

275 of 749 indexed Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4 of 28,707 conditions by registered trial count.

749 US clinical trials · 275 currently recruiting · #4 of 28,707 conditions by registered trial count

Prostate Cancer: 749 US clinical trials tracked, 275 recruiting.

Prostate Cancer is the subject of 749 registered US clinical trials on ClinicalTrials.gov, 275 of them currently open to new participants. 75 are in Phase 3-4 (later-stage) and 344 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 53 of these trials.

Enrollment posture brief

Registry condition prostate-cancer

OPEN 275 | RECR 37% | LATE 75 | EARLY 344 | RANK #4 | SPON 53

Nearest open-share peer: Chronic Disease (37% recruiting · 49 trials)

Cancer44.9%Prostate Cancer (this)37%Depression35.7%Hypertension32.2%HIV Infections9.1%
Open-enrollment share among volume-matched conditions near Prostate Cancer

Prostate Cancer lists 275 open slots (37% of 749 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Prostate Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostate Cancer recruits in line with its size-band peers.

    275 of 749 indexed trials (36.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostate Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 53 of 749 trials (7.1%). 283 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostate Cancer enrolment sits around 82 participants.

    Median target enrolment is 82 among the 736 trials that report a genuine target (sentinel values excluded). 389 of those (52.9%) plan for fewer than 100 participants.

  4. Prostate Cancer research is mostly interventional.

    628 interventional and 121 observational studies make up this index (83.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1156Phase 2188Phase 362Phase 413

Open and recent trials

749 total, page 15 of 15

COMPLETED Phase 2 15 participants

Study of Bortezomib and Docetaxel for Patients With Hormone Refractory Prostate Cancer

University of Southern California

NCT00183937

COMPLETED NA 15 participants

UroLift System With SAbR for Prostate Cancer and BPH

University of Texas Southwestern Medical Center

NCT05311527

COMPLETED Phase 1 14 participants

68-Ga PSMA 11 PET/MRI and 68-Ga RM2 PET/MRI for Evaluation of Prostate Cancer Response to HIFU Therapy

Andrei Iagaru

NCT03949517

COMPLETED 14 participants

Collection of Blood Specimens for Circulating Tumor Cell Analysis

Viatar

NCT01943500

COMPLETED 14 participants

Magnetic Resonance Imaging of Lymph Nodes Using Ferumoxytol in Patients With Primary Prostate or Breast Cancer

Massachusetts General Hospital

NCT00087347

COMPLETED Phase 1 14 participants

A Pre-surgical Study of LDE225 in Men With High-risk Localized Prostate Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT02111187

COMPLETED Phase 1 13 participants

Dendritic Cell Vaccine Study (DC/PC3) for Prostate Cancer

Rockefeller University

NCT00345293

COMPLETED Phase 2 13 participants

Combining EPI-7386 With Enzalutamide and Androgen Deprivation Therapy for Metastatic Hormone-Sensitive Prostate Cancer

Pedro Barata, MD, MSc

NCT06312670

COMPLETED NA 13 participants

Exercise Intervention Among Men With Prostate Cancer Initiating Androgen Deprivation Therapy

Dana-Farber Cancer Institute

NCT03070145

COMPLETED Phase 2 13 participants

Utilizing A Genomic Sig for "BRCAness" to Eval the Efficacy of Satraplatin in Men With Met. Castration Resistant Prostate Ca

William K. Oh

NCT01289067

COMPLETED NA 12 participants

Transpelvic Magnetic Stimulation to Improve Urogenital Function

VA Office of Research and Development

NCT04488068

COMPLETED Early Phase 1 12 participants

Cisplatin in Castration Resistant Prostate Cancer

University of Rochester

NCT03275857

COMPLETED Phase 1 12 participants

Diindolylmethane in Treating Patients With Nonmetastatic Prostate Cancer That Has Not Responded To Previous Hormone Therapy

Barbara Ann Karmanos Cancer Institute

NCT00305747

COMPLETED Phase 1 12 participants

Phase 1 Trial of PAN-301-1 (SNS-301) in Cancer Patients

Sensei Biotherapeutics

NCT03120832

COMPLETED Phase 2 12 participants

Study of Focal Cryoablation in Low-Risk Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT00774436

COMPLETED 12 participants

Ketogenic Diet and Prostate Cancer Surveillance Pilot

University of Maryland, Baltimore

NCT03194516

COMPLETED Phase 1 12 participants

AGN-CognI.Q Acute Dose Safety and Pharmacokinetics Dose-Response in Prostate Cancer Patients

Milton S. Hershey Medical Center

NCT05375539

COMPLETED Phase 4 12 participants

Study of Nerve Reconstruction Using AVANCE in Subjects Who Undergo Robotic Assisted Prostatectomy for Treatment of Prostate Cancer

Axogen Corporation

NCT00953277

COMPLETED Early Phase 1 12 participants

Streaming Web-based Exercise At Home: A Pilot Study

Celina Shirazipour

NCT04282967

COMPLETED NA 11 participants

Transrectal Ultrasound (TRUS) in Finding Tumors During Robotic-Assisted Laparoscopic Surgery

University of Southern California

NCT01495130

COMPLETED Phase 2 11 participants

Study of TRC105 With Abiraterone and With Enzalutamide in Prostate Cancer Patients Progressing on Therapy

Cedars-Sinai Medical Center

NCT03418324

COMPLETED Phase 1 11 participants

Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced Cancer

National Cancer Institute (NCI)

NCT03384316

COMPLETED NA 11 participants

PET Scanning to Evaluate Zoledronate Efficacy in Metastatic Prostate Cancer

Barbara Ann Karmanos Cancer Institute

NCT01205646

COMPLETED Phase 2 10 participants

An Extension Study Administering YM155 to Subjects Previously Enrolled in Another Protocol Administering YM155

Astellas Pharma

NCT00818480

COMPLETED NA 10 participants

A Pilot Study to Assess the Immunogenicity of Candidate PSA Peptides for a Prostate Cancer Vaccine

University of Arkansas

NCT02485964

COMPLETED NA 10 participants

Feasibility of Using SPECT/CT Imaging to Map Lymphatic Drainage Patterns in Prostate Cancer Patients

University of California, San Francisco

NCT01008969

COMPLETED Phase 1 10 participants

BMTP-11 in Patients With Castrate-Resistant Prostate Cancer With Bone Mets

M.D. Anderson Cancer Center

NCT00872157

COMPLETED NA 9 participants

Fusion Targeted Biopsy of the Prostate

Emory University

NCT02013414

COMPLETED Phase 1 9 participants

ARN 509 Plus Everolimus in Men With Progressive Metastatic Castration-Resistant Prostate Cancer After Treatment With Abiraterone Acetate

Memorial Sloan Kettering Cancer Center

NCT02106507

COMPLETED 8 participants

A Pilot Study of [Ga-68]PSMA PET/MRI for the Assessment of PSMA-positive Tumors

Case Comprehensive Cancer Center

NCT02978586

COMPLETED Phase 2 7 participants

Enzalutamide and Hormone Therapy Before, During, and After Radiation for High Risk Localized Prostate Cancer

University of Texas Southwestern Medical Center

NCT02064582

COMPLETED Phase 2 7 participants

FACBC Prostate Therapy Response

Emory University

NCT02830880

COMPLETED NA 6 participants

Peripheral vs. Selective Tumor Marker Venous Sampling in Prostate Cancer

Abramson Cancer Center at Penn Medicine

NCT02479945

COMPLETED NA 6 participants

Focal Prostate Radio-Frequency Ablation

H. Lee Moffitt Cancer Center and Research Institute

NCT02328807

COMPLETED Phase 2 5 participants

Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors.

Seagen

NCT03245736

COMPLETED Phase 3 2 participants

Extension of SoluMatrix TM Abiraterone Acetate in Patients Who Completed Study Number CHL-AA-201

GU Research Network

NCT02887976

COMPLETED

To Explore Racial Differences in Potential Risk Factors for Developing Prostate Cancer in the VA Population.

US Department of Veterans Affairs

NCT00007579

COMPLETED Phase 2

Dolastatin 10 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Previous Hormone Therapy

Barbara Ann Karmanos Cancer Institute

NCT00003626

COMPLETED Phase 1

Lycopene In Preventing of Prostate Cancer

University of Illinois at Chicago

NCT00006078

COMPLETED Phase 2

Calcifidol Therapy in Men With Cancer

US Department of Veterans Affairs

NCT00018538

COMPLETED Phase 2

CCI-779 in Treating Patients With Prostate Cancer

Jonsson Comprehensive Cancer Center

NCT00012142

COMPLETED Phase 2

Combination Chemotherapy Plus Warfarin in Treating Patients With Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT00014352

COMPLETED Phase 2

Vaccine Therapy With or Without Docetaxel in Treating Patients With Metastatic Prostate Cancer

National Cancer Institute (NCI)

NCT00045227

COMPLETED Phase 3

Hormone Therapy Compared With Combination Chemotherapy in Treating Patients With Prostate Cancer

Eastern Cooperative Oncology Group

NCT00027859

COMPLETED Phase 3

Cyproterone Acetate in Treating Hot Flashes Following Surgical or Chemical Castration for Prostate Cancer

Barr Laboratories

NCT00005623

COMPLETED Phase 2

Trastuzumab in Treating Patients With Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT00003740

COMPLETED Phase 1

Combination Chemotherapy With Suramin Plus Doxorubicin in Treating Patients With Advanced Solid Tumors

Mayo Clinic

NCT00003038

COMPLETED Phase 1

Testosterone in Treating Patients With Progressive Prostate Cancer That No Longer Responds to Hormone Therapy

Memorial Sloan Kettering Cancer Center

NCT00006044

COMPLETED NA

Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Diagnosing the Extent of Disease in Patients With Prostate Cancer

American College of Radiology Imaging Network

NCT00032058

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Phase Distribution

PhaseTrial count
Phase 1 156
Phase 2 188
Phase 3 62
Phase 4 13

Named interventions

Most-linked intervention names on Prostate Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Enzalutamide Drug
21 trials
Prednisone Drug
15 trials
docetaxel Drug
13 trials
Placebo Drug
13 trials
Docetaxel Drug
11 trials
Radiation Therapy Radiation
9 trials
Darolutamide Drug
9 trials
radiation therapy Radiation
8 trials

US sites by state

Facility locations filed on Prostate Cancer trials. A trial with sites in several states counts in each.

New York 207 trials
California 202 trials
Florida 118 trials
Maryland 112 trials
Texas 98 trials
Pennsylvania 91 trials
Massachusetts 91 trials
Illinois 89 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Prostate Cancer page

749 registered trials, 275 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Prostate Cancer condition card totals 749 registered trials; most-linked intervention Enzalutamide; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.