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NCT00183937 · ClinicalTrials.gov registry record · Phase 2

Study of Bortezomib and Docetaxel for Patients With Hormone Refractory Prostate Cancer

A Phase 2 study of Prostate Cancer, sponsored by University of Southern California.

Completed
Registry status
Phase 2
Development phase
15
Enrollment target
1
Study location

NCT00183937 is a Phase 2 study of Prostate Cancer that has completed, run by University of Southern California. The registered enrollment target is 15 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00183937, a Phase 2 study of Prostate Cancer, has completed, sponsored by University of Southern California.

COMPLETED
Registry status
Phase 2
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

This study is for patients who have been treated with surgical removal of the testes or hormone therapy (Lupron or Zoladex) and whose prostate cancer has worsened despite this treatment. PS 341 is a type of drug known as a "proteasome inhibitor." By inhibiting the "proteasome" in cancer cells, PS-341 alters the way those cells divide). We hope to learn whether this combination chemotherapy decreases cancer symptoms and tests (prostate specific antigen, also called PSA), and to determine how frequently serious side effects might occur with this treatment for this stage of prostate cancer.

Conditions Studied

Interventions

  • DRUG Docetaxel
  • DRUG PS 341

Study Locations (1)

California

  • USC/Norris Comprehensive Cancer Center - Los Angeles

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2005-04-30
Est. Completion 2012-06-11
Phase Phase 2

Sponsor

University of Southern California

617 total trials

What the Registry Record Tells You About NCT00183937

The ClinicalTrials.gov registry entry for NCT00183937 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (98% lower). The listed sponsor is University of Southern California, which has 617 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 2 interventions - of which Docetaxel is the first listed.

NCT00183937 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT00183937 about?

NCT00183937 is a clinical study titled "Study of Bortezomib and Docetaxel for Patients With Hormone Refractory Prostate Cancer". This study is for patients who have been treated with surgical removal of the testes or hormone therapy (Lupron or Zoladex) and whose prostate cancer has worsened despite this treatment. PS 341 is a type of drug known as a "proteasome inhibitor." By inhibiting the "proteasome" in cancer cells, PS-3...

What is the current status of trial NCT00183937?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2005-04-30. Estimated completion is 2012-06-11.

What conditions does trial NCT00183937 study?

This clinical trial studies the following conditions: Prostate Cancer.

What interventions are being tested in trial NCT00183937?

The interventions under investigation include: Docetaxel (DRUG), PS 341 (DRUG).

Who is sponsoring clinical trial NCT00183937?

This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00183937 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.