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NCT00183937 · ClinicalTrials.gov registry record · Phase 2
Study of Bortezomib and Docetaxel for Patients With Hormone Refractory Prostate Cancer
A Phase 2 study of Prostate Cancer, sponsored by University of Southern California.
- Completed
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT00183937: Completed Phase 2 study of Prostate Cancer, sponsored by University of Southern California.
NCT00183937 is a Phase 2 study of Prostate Cancer that has completed, run by University of Southern California. The registered enrollment target is 15 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00183937, a Phase 2 study of Prostate Cancer, has completed, sponsored by University of Southern California.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is for patients who have been treated with surgical removal of the testes or hormone therapy (Lupron or Zoladex) and whose prostate cancer has worsened despite this treatment. PS 341 is a type of drug known as a "proteasome inhibitor." By inhibiting the "proteasome" in cancer cells, PS-341 alters the way those cells divide). We hope to learn whether this combination chemotherapy decreases cancer symptoms and tests (prostate specific antigen, also called PSA), and to determine how frequently serious side effects might occur with this treatment for this stage of prostate cancer.
Primary Outcome
Participants should be reevaluated for PSA response every 21 days. A confirmatory PSA level should be obtained 3-4 weeks following initial documentation of a PSA response.
Conditions Studied
Interventions
- DRUG Docetaxel
- DRUG PS 341
Study Locations (1)
California
- USC/Norris Comprehensive Cancer Center - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2005-04-30 |
| Est. Completion | 2012-06-11 |
| Phase | Phase 2 |
What the finished NCT00183937 record still lists
NCT00183937 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 2 interventions - of which Docetaxel is the first listed.
NCT00183937 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00183937 about?
NCT00183937 is a clinical study titled "Study of Bortezomib and Docetaxel for Patients With Hormone Refractory Prostate Cancer". This study is for patients who have been treated with surgical removal of the testes or hormone therapy (Lupron or Zoladex) and whose prostate cancer has worsened despite this treatment. PS 341 is a type of drug known as a "proteasome inhibitor." By inhibiting the "proteasome" in cancer cells, PS-3...
What is the current status of trial NCT00183937?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2005-04-30. Estimated completion is 2012-06-11.
What conditions does trial NCT00183937 study?
This clinical trial studies the following conditions: Prostate Cancer.
What interventions are being tested in trial NCT00183937?
The interventions under investigation include: Docetaxel (DRUG), PS 341 (DRUG).
Who is sponsoring clinical trial NCT00183937?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00183937 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Prostate Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00183937's enrollment target sits among peer trials
15 687th of 735 higher than 44 of 735 other Prostate Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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