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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Primary Lateral Sclerosis: early-phase trial registry

5 of 10 indexed Primary Lateral Sclerosis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

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10 US clinical trials · 5 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Primary Lateral Sclerosis: 10 US clinical trials tracked, 5 recruiting.

Primary Lateral Sclerosis is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is University of Miami, running 3 of these trials.

Enrollment posture brief

Registry condition primary-lateral-sclerosis

OPEN 5 | RECR 50% | LATE 0 | EARLY 1 | RANK #1724 | SPON 3

Volume-matched condition peers

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Acute Leukemia of Ambiguous 80%Primary Lateral Sclerosi (th…50%Achondroplasia40%Accelerated Phase Chronic My20%Accidental Fall20%
Open-enrollment share among volume-matched conditions near Primary Lateral Sclerosis

Primary Lateral Sclerosis lists 5 open slots (50% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Primary Lateral Sclerosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Primary Lateral Sclerosis is recruiting above its size-band peers.

    5 of 10 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Primary Lateral Sclerosis research.

    University of Miami accounts for 3 of 10 trials (30%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Typical Primary Lateral Sclerosis enrolment sits around 100 participants.

    Median target enrolment is 100 among the 10 trials that report a genuine target (sentinel values excluded). 5 of those (50%) plan for fewer than 100 participants.

  4. Primary Lateral Sclerosis research leans observational.

    2 interventional and 8 observational studies make up this index (20% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21

Phase Distribution

PhaseTrial count
Phase 2 1

Top Sponsors

University of Miami 3 trials
National Institute of Neurological Disorders and Stroke (NINDS) 2 trials
Milton S. Hershey Medical Center 1 trials
University of Minnesota 1 trials
University of Missouri-Columbia 1 trials
Duke University 1 trials
Boston Children's Hospital 1 trials

Named interventions

Most-linked intervention names on Primary Lateral Sclerosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Levetiracetam Biological
1 trials
Digital Speech and Handwriting Assessment Behavioral
1 trials
Whole-body Electrical Muscle Stimulation Exercise Device
1 trials

US sites by state

Facility locations filed on Primary Lateral Sclerosis trials. A trial with sites in several states counts in each.

Florida 4 trials
Pennsylvania 3 trials
Kansas 3 trials
Texas 2 trials
New York 2 trials
North Carolina 2 trials
Minnesota 2 trials
Maryland 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Related

Read our methodology - how this data is sourced, computed, and verified.

What to do with this Primary Lateral Sclerosis page

10 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Primary Lateral Sclerosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • University of Miami sponsors the most Primary Lateral Sclerosis trials on record, review their full trial history before evaluating a specific study. See University of Miami's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Primary Lateral Sclerosis condition card totals 10 registered trials; most-linked intervention Levetiracetam; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.