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ClinicalTrials.gov 8 recruiting now early-phase tilt small index

Acute Leukemia of Ambiguous Lineage: early-phase trial registry

8 of 10 indexed Acute Leukemia of Ambiguous Lineage trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 8 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Acute Leukemia of Ambiguous Lineage: 10 US clinical trials tracked, 8 recruiting.

Acute Leukemia of Ambiguous Lineage is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Fred Hutchinson Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition acute-leukemia-of-ambiguous-lineage

OPEN 8 | RECR 80% | LATE 0 | EARLY 10 | RANK #1724 | SPON 3

Nearest open-share peer: Ablation (80% recruiting · 5 trials)

Acute Leukemia of Ambigu (th…80%Achondroplasia40%Acute Myeloid Leukemia Post 40%Accelerated Phase Chronic My20%Accidental Fall20%
Open-enrollment share among volume-matched conditions near Acute Leukemia of Ambiguous Lineage

Acute Leukemia of Ambiguous Lineage lists 8 open slots (80% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Acute Leukemia of Ambiguous Lineage on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Acute Leukemia of Ambiguous Lineage is recruiting above its size-band peers.

    8 of 10 indexed trials (80%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Acute Leukemia of Ambiguous Lineage research.

    Fred Hutchinson Cancer Center accounts for 3 of 10 trials (30%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Most Acute Leukemia of Ambiguous Lineage trials plan to enrol fewer than 100 people.

    Median target enrolment is 68 among the 10 trials that report a genuine target (sentinel values excluded). 7 of those (70%) plan for fewer than 100 participants.

  4. Acute Leukemia of Ambiguous Lineage research is mostly interventional.

    10 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 26

Open and recent trials

10 total, page 1 of 1

RECRUITING Phase 1 447 participants

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Syndax Pharmaceuticals

NCT04065399

RECRUITING Phase 1 263 participants

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

Kura Oncology

NCT04067336

RECRUITING Phase 2 153 participants

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

National Cancer Institute (NCI)

NCT06317662

RECRUITING Phase 2 68 participants

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT03779854

RECRUITING Phase 2 54 participants

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Fred Hutchinson Cancer Center

NCT06013423

RECRUITING Phase 1 27 participants

Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant

City of Hope Medical Center

NCT06575296

RECRUITING Phase 1 24 participants

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

St. Jude Children's Research Hospital

NCT06177067

RECRUITING Phase 2 20 participants

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

Fred Hutchinson Cancer Center

NCT07046078

COMPLETED Phase 2 78 participants

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

National Cancer Institute (NCI)

NCT02828358

COMPLETED Phase 2 16 participants

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

M.D. Anderson Cancer Center

NCT02135874

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 6

Named interventions

Most-linked intervention names on Acute Leukemia of Ambiguous Lineage records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
5 trials
Cytarabine Drug
4 trials
Bone Marrow Aspiration Procedure
3 trials
Cyclophosphamide Drug
3 trials
Azacitidine Drug
2 trials
Bone Marrow Biopsy Procedure
2 trials
intrathecal (IT) chemotherapy Drug
1 trials
cobicistat Drug
1 trials

US sites by state

Facility locations filed on Acute Leukemia of Ambiguous Lineage trials. A trial with sites in several states counts in each.

California 7 trials
Pennsylvania 4 trials
Colorado 4 trials
Washington 3 trials
Ohio 3 trials
New York 3 trials
Massachusetts 3 trials
Georgia 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Acute Leukemia of Ambiguous Lineage page

10 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 8 Acute Leukemia of Ambiguous Lineage trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Fred Hutchinson Cancer Center sponsors the most Acute Leukemia of Ambiguous Lineage trials on record, review their full trial history before evaluating a specific study. See Fred Hutchinson Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Leukemia of Ambiguous Lineage condition card totals 10 registered trials; most-linked intervention Biospecimen Collection; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.