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ClinicalTrials.gov 4 recruiting now full pipeline small index

Prehypertension: full-pipeline trial registry

4 of 14 indexed Prehypertension trials are currently recruiting.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 4 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Prehypertension: 14 US clinical trials tracked, 4 recruiting.

Prehypertension is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 2 of these trials.

Enrollment posture brief

Registry condition prehypertension

OPEN 4 | RECR 29% | LATE 1 | EARLY 1 | RANK #1230 | SPON 2

Nearest open-share peer: Acne Scars (29% recruiting · 7 trials)

Acute Respiratory Failure35.7%Adherence, Medication35.7%Prehypertension (this)29%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Prehypertension

Prehypertension lists 4 open slots (29% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Prehypertension on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Prehypertension is recruiting below its size-band peers.

    4 of 14 indexed trials (28.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prehypertension trials is spread across many organizations.

    Duke University accounts for 2 of 14 trials (14.3%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prehypertension enrolment sits around 99 participants.

    Median target enrolment is 99 among the 14 trials that report a genuine target (sentinel values excluded). 8 of those (57.1%) plan for fewer than 100 participants.

  4. Prehypertension research is mostly interventional.

    11 interventional and 3 observational studies make up this index (78.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21Phase 41

Open and recent trials

14 total, page 1 of 1

RECRUITING 5,000 participants

Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study

Duke University

NCT06595251

RECRUITING 1,000 participants

Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study

Duke University

NCT06596265

RECRUITING NA 120 participants

Sympathetic Overactivity in Post-traumatic Stress Disorder

Emory University

NCT01627301

RECRUITING NA 80 participants

Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health

Skidmore College

NCT06363305

ACTIVE NOT RECRUITING NA 528 participants

Equity in Prevention and Progression of Hypertension by Addressing Barriers to Nutrition and Physical activitY

University of Alabama at Birmingham

NCT05367544

ACTIVE NOT RECRUITING NA 110 participants

HELP-HY: Health Education and sLeep Program in HYpertension

Mayo Clinic

NCT03255746

ACTIVE NOT RECRUITING NA 36 participants

Watermelon Dose Response Blood Pressure Study

Clinical Nutrition Research Center, Illinois Institute of Technology

NCT05892328

COMPLETED NA 300 participants

Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients

Massachusetts General Hospital

NCT02551640

COMPLETED Phase 2 99 participants

Center of Research Translation (CORT) Project 2

University of Alabama at Birmingham

NCT02038179

COMPLETED NA 60 participants

Macronutrient Effects on Alzheimer's Disease (MEAL-2)

Wake Forest University Health Sciences

NCT02463084

COMPLETED NA 50 participants

Study: Effects of Strawberries on Blood Pressure

University of California, Davis

NCT01190319

COMPLETED Phase 4 44 participants

Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)

University of Colorado, Boulder

NCT01595516

COMPLETED 30 participants

A Biomarker to Detect Salt Sensitivity

University of Minnesota

NCT03147170

COMPLETED NA 9 participants

When the Kidney Reacts to Nutritional Changes

Rockefeller University

NCT04142138

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 4 1

Named interventions

Most-linked intervention names on Prehypertension records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Health Education Behavioral
2 trials
Placebo Drug
2 trials
Strawberry Beverage Other
1 trials
High and low salt diets Diagnostic test
1 trials
FeatForward App (on study smartphone) Other
1 trials
DASH Other
1 trials
High Diet Other
1 trials
Low Diet Other
1 trials

US sites by state

Facility locations filed on Prehypertension trials. A trial with sites in several states counts in each.

New York 2 trials
Minnesota 2 trials
Florida 2 trials
Alabama 2 trials
North Carolina 1 trials
Massachusetts 1 trials
Illinois 1 trials
Georgia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Prehypertension page

14 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Prehypertension trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Duke University sponsors the most Prehypertension trials on record, review their full trial history before evaluating a specific study. See Duke University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Prehypertension condition card totals 14 registered trials; most-linked intervention Health Education; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.