Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 4 recruiting now official registry

Acromegaly clinical trials

4 of 14 indexed Acromegaly trials are currently recruiting.

14 US clinical trials · 4 currently recruiting

Acromegaly is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Crinetics Pharmaceuticals, running 3 of these trials.

The research picture

Acromegaly has 14 registered US clinical trials, 4 of them open to new participants right now, about 29% of the total.

4
recruiting participants now
29%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
3
top sponsor: Crinetics Pharmaceuticals
Phase 11Phase 23Phase 34Phase 41

Active & Recent Trials

14 total, page 1 of 1

RECRUITING Phase 3 119 participants

A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

Debiopharm International

NCT06930625

RECRUITING Phase 2 60 participants

ALXN2420 Versus Placebo in Combination With Somatostatin Analogs in Participants With Acromegaly

Alexion Pharmaceuticals

NCT07037420

RECRUITING Phase 1 45 participants

Study of MAR002 in Healthy Men

Marea Therapeutics

NCT07195175

RECRUITING NA 9 participants

Diet in the Management of Acromegaly

Cedars-Sinai Medical Center

NCT05401084

ACTIVE NOT RECRUITING Phase 3 111 participants

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2)

Crinetics Pharmaceuticals

NCT05192382

ACTIVE NOT RECRUITING Phase 3 58 participants

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly

Crinetics Pharmaceuticals

NCT04837040

ACTIVE NOT RECRUITING Phase 2 43 participants

A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)

Crinetics Pharmaceuticals

NCT04261712

ACTIVE NOT RECRUITING 20 participants

Peri-operative Dynamics of the Growth Hormone Axis in Subjects With Acromegaly

Cedars-Sinai Medical Center

NCT00921609

COMPLETED 520 participants

Treatment Patterns and Treatment Outcomes for Acromegaly

Columbia University

NCT03043586

COMPLETED Phase 4 100 participants

A Study To Compare The Efficacy And Safety Of Pegvisomant To That Of Sandostatin Lar Depot In Patients With Acromegaly

Pfizer

NCT00068042

COMPLETED 77 participants

Bone MicroArchitecture in Acromegaly

Columbia University

NCT03225040

COMPLETED NA 75 participants

Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency

Massachusetts General Hospital

NCT00182091

COMPLETED Phase 3 72 participants

A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With Acromegaly

Camurus AB

NCT04076462

COMPLETED Phase 2 5 participants

Sandostatin LAR Depot vs. Surgery for Treating Acromegaly

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00001860

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 3 4
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Acromegaly Trial Landscape

14 indexed Acromegaly studies · 4 recruiting (29%).

Phase mix: 5 late (III/IV) vs 4 early (I/II).

Top sponsor: Crinetics Pharmaceuticals (3 trials), 9 others listed. 14 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Acromegaly?

PlainTrial tracks 14 US clinical trials for Acromegaly, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Acromegaly?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.