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NCT04144920 · ClinicalTrials.gov registry record · NA

Evaluating the Acute Glycemic Response to Different Strategies of Breaking Up Sedentary Time

A NA study of Pre Diabetes and Postprandial Hyperglycemia, sponsored by Arizona State University.

Completed
Registry status
NA
Development phase
12
Enrollment target
1
Study location

NCT04144920 is a NA study of Pre Diabetes and Postprandial Hyperglycemia that has completed, run by Arizona State University. The registered enrollment target is 12 participants, below the 729-participant average among 59 other Pre Diabetes trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04144920, a NA study of Pre Diabetes and Postprandial Hyperglycemia, has completed, sponsored by Arizona State University.

COMPLETED
Registry status
NA
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

This study aims to determine the most effective strategy of reducing sedentary behavior to improve health. Specifically, we aim to answer the following questions: (a) To determine if there is a significant difference in acute post-prandial glucose response between continuous sitting and two intermittent standing regimes (high frequency, low duration breaks (HFLD) and low frequency, high duration breaks (LFHD)). We hypothesize that intermittent standing (combined HFLD breaks and LFHD breaks regimes) will result in lower overall acute post-prandial glucose compared to continuous sitting. (b) To determine if there is a significant difference in acute post-prandial glucose response between two strategies to reduce sitting with standing (HFLD standing breaks vs. LFHD standing breaks). We hypothesize that the HFLD breaks condition will elicit lower acute post-prandial glucose level compared to the LFHD breaks condition. All eligible participants will be consented and subjected to all three study conditions: (i) Uninterrupted sitting, (ii) HFLD breaks, and (iii) LFHD breaks. The order at which participants were subjected to these conditions will be randomly determined and each condition were performed a week apart. Standardized meals (breakfast and lunch) will be provided during each lab visit and participants will be then be asked to perform their usual work activity using a sit-stand workstation in the lab. Depending on their assigned condition, the participants will be prompted to stand or sit for a given period of time. A continuous glucose monitor will be used to measure glucose response to the intervention while an activPAL device will be used to make sure that participants are compliant with the study protocol.

Interventions

  • BEHAVIORAL CS: Continuous sitting
  • BEHAVIORAL HFLD: HIgh frequency, low duration standing breaks
  • BEHAVIORAL LFHD: Low frequency, high duration standing breaks

Study Locations (1)

Arizona

  • Arizona State University - Tempe

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2018-08-01
Est. Completion 2019-06-14
Phase NA

Sponsor

Arizona State University

187 total trials

What the Registry Record Tells You About NCT04144920

The ClinicalTrials.gov registry entry for NCT04144920 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 729-participant average among 59 other Pre Diabetes trials with a reported enrollment target (98% lower). The listed sponsor is Arizona State University, which has 187 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Pre Diabetes appearing as the primary indexed condition, and to 3 interventions - of which CS: Continuous sitting is the first listed.

NCT04144920 reports 1 study location spanning 1 distinct geographic area - top geographies include Arizona.

Frequently Asked Questions

What is clinical trial NCT04144920 about?

NCT04144920 is a clinical study titled "Evaluating the Acute Glycemic Response to Different Strategies of Breaking Up Sedentary Time". This study aims to determine the most effective strategy of reducing sedentary behavior to improve health. Specifically, we aim to answer the following questions: (a) To determine if there is a significant difference in acute post-prandial glucose response between continuous sitting and two intermit...

What is the current status of trial NCT04144920?

This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2018-08-01. Estimated completion is 2019-06-14.

What conditions does trial NCT04144920 study?

This clinical trial studies the following conditions: Pre Diabetes, Postprandial Hyperglycemia.

What interventions are being tested in trial NCT04144920?

The interventions under investigation include: CS: Continuous sitting (BEHAVIORAL), HFLD: HIgh frequency, low duration standing breaks (BEHAVIORAL), LFHD: Low frequency, high duration standing breaks (BEHAVIORAL).

Who is sponsoring clinical trial NCT04144920?

This trial is sponsored by Arizona State University, which has 187 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04144920 being conducted?

This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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