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NCT04144920 · ClinicalTrials.gov registry record · NA
Evaluating the Acute Glycemic Response to Different Strategies of Breaking Up Sedentary Time
A NA study of PreDiabetes and Postprandial Hyperglycemia, sponsored by Arizona State University.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT04144920: Completed NA study of PreDiabetes and Postprandial Hyperglycemia, sponsored by Arizona State University.
NCT04144920 is a NA study of PreDiabetes and Postprandial Hyperglycemia that has completed, run by Arizona State University. The registered enrollment target is 12 participants, below the 701-participant average among 149 other PreDiabetes trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04144920, a NA study of PreDiabetes and Postprandial Hyperglycemia, has completed, sponsored by Arizona State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to determine the most effective strategy of reducing sedentary behavior to improve health. Specifically, we aim to answer the following questions: (a) To determine if there is a significant difference in acute post-prandial glucose response between continuous sitting and two intermittent standing regimes (high frequency, low duration breaks (HFLD) and low frequency, high duration breaks (LFHD)). We hypothesize that intermittent standing (combined HFLD breaks and LFHD breaks regimes) will result in lower overall acute post-prandial glucose compared to continuous sitting. (b) To determine if there is a significant difference in acute post-prandial glucose response between two strategies to reduce sitting with standing (HFLD standing breaks vs. LFHD standing breaks). We hypothesize that the HFLD breaks condition will elicit lower acute post-prandial glucose level compared to the LFHD breaks condition. All eligible participants will be consented and subjected to all three study conditions: (i) Uninterrupted sitting, (ii) HFLD breaks, and (iii) LFHD breaks. The order at which participants were subjected to these conditions will be randomly determined and each condition were performed a week apart. Standardized meals (breakfast and lunch) will be provided during each lab visit and participants will be then be asked to perform their usual work activity using a sit-stand workstation in the lab. Depending on their assigned condition, the participants will be prompted to stand or sit for a given period of time. A continuous glucose monitor will be used to measure glucose response to the intervention while an activPAL device will be used to make sure that participants are compliant with the study protocol.
Primary Outcome
iAUC will be calculated using the trapezoidal method.
Conditions Studied
Interventions
- BEHAVIORAL CS: Continuous sitting
- BEHAVIORAL HFLD: HIgh frequency, low duration standing breaks
- BEHAVIORAL LFHD: Low frequency, high duration standing breaks
Study Locations (1)
Arizona
- Arizona State University - Tempe
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2018-08-01 |
| Est. Completion | 2019-06-14 |
| Phase | NA |
What the finished NCT04144920 record still lists
NCT04144920 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 701-participant average among 149 other PreDiabetes trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with PreDiabetes appearing as the primary indexed condition, and to 3 interventions - of which CS: Continuous sitting is the first listed.
NCT04144920 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT04144920 about?
NCT04144920 is a clinical study titled "Evaluating the Acute Glycemic Response to Different Strategies of Breaking Up Sedentary Time". This study aims to determine the most effective strategy of reducing sedentary behavior to improve health. Specifically, we aim to answer the following questions: (a) To determine if there is a significant difference in acute post-prandial glucose response between continuous sitting and two intermit...
What is the current status of trial NCT04144920?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2018-08-01. Estimated completion is 2019-06-14.
What conditions does trial NCT04144920 study?
This clinical trial studies the following conditions: PreDiabetes, Postprandial Hyperglycemia.
What interventions are being tested in trial NCT04144920?
The interventions under investigation include: CS: Continuous sitting (BEHAVIORAL), HFLD: HIgh frequency, low duration standing breaks (BEHAVIORAL), LFHD: Low frequency, high duration standing breaks (BEHAVIORAL).
Who is sponsoring clinical trial NCT04144920?
This trial is sponsored by Arizona State University, which has 187 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04144920 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT04144920's enrollment target sits among peer trials
12 147th of 149 higher than 3 of 149 other PreDiabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other PreDiabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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