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NCT05534126 · ClinicalTrials.gov registry record · NA
Enhancing Cognitive Processing Therapy for Posttraumatic Stress Disorder Via Stellate Ganglion Block Treatment: A Pilot Trial
A NA study of Chronic Pain and Post Traumatic Stress Disorder, sponsored by Rush University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05534126: Completed NA study of Chronic Pain and Post Traumatic Stress Disorder, sponsored by Rush University Medical Center.
NCT05534126 is a NA study of Chronic Pain and Post Traumatic Stress Disorder that has completed, run by Rush University Medical Center. The registered enrollment target is 60 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05534126, a NA study of Chronic Pain and Post Traumatic Stress Disorder, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Cognitive Processing Therapy (CPT) is an effective first-line, evidence-based treatment for posttraumatic stress disorder (PTSD). Despite its well-demonstrated effectiveness, research has shown that approximately two-thirds of individuals continue to meet the diagnostic criteria for PTSD even after successful treatment completion. Stellate Ganglion Block (SGB) treatment, involving a local anesthesia injection to the stellate ganglion (around the lower base of the neck), has been shown to block its pain signal transmissions. Prior case studies and reviews have provided evidence for reducing PTSD symptoms with SGB treatment. However, studies to date have only examined SGB as a standalone intervention. The utility of combining CPT with concurrent SGB treatment remains unknown, although it is plausible that the combination of the two treatments can improve the effectiveness of CPT alone. The present study aims to test this hypothesis by comparing either a combined 1-week massed CPT + SGB treatment and 1-week massed CPT + placebo treatment (saline injection) using a randomized controlled trial design.
Primary Outcome
Clinician Administered Assessment of PTSD
Conditions Studied
Interventions
- PROCEDURE Placebo
- PROCEDURE Stellate Ganglion Block Treatment
Study Locations (1)
Illinois
- Rush University Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2022-11-01 |
| Est. Completion | 2025-09-30 |
| Phase | NA |
What the finished NCT05534126 record still lists
NCT05534126 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (92% lower).
The record links to 2 conditions, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05534126 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05534126 about?
NCT05534126 is a clinical study titled "Enhancing Cognitive Processing Therapy for Posttraumatic Stress Disorder Via Stellate Ganglion Block Treatment: A Pilot Trial". Cognitive Processing Therapy (CPT) is an effective first-line, evidence-based treatment for posttraumatic stress disorder (PTSD). Despite its well-demonstrated effectiveness, research has shown that approximately two-thirds of individuals continue to meet the diagnostic criteria for PTSD even after ...
What is the current status of trial NCT05534126?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2022-11-01. Estimated completion is 2025-09-30.
What conditions does trial NCT05534126 study?
This clinical trial studies the following conditions: Chronic Pain, Post Traumatic Stress Disorder.
What interventions are being tested in trial NCT05534126?
The interventions under investigation include: Placebo (PROCEDURE), Stellate Ganglion Block Treatment (PROCEDURE).
Who is sponsoring clinical trial NCT05534126?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05534126 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05534126's enrollment target sits among peer trials
60 176th of 301 higher than 112 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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