Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05950035 · ClinicalTrials.gov registry record · NA
An Efficient Treatment for Posttraumatic Injury for Firefighters
A NA study of Post Traumatic Stress Disorder and Insomnia, sponsored by Palo Alto Veterans Institute for Research.
- Completed
- Registry status
- NA
- Development phase
- 49
- Enrollment target
- 1
- Study location
NCT05950035: Completed NA study of Post Traumatic Stress Disorder and Insomnia, sponsored by Palo Alto Veterans Institute for Research.
NCT05950035 is a NA study of Post Traumatic Stress Disorder and Insomnia that has completed, run by Palo Alto Veterans Institute for Research. The registered enrollment target is 49 participants, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05950035, a NA study of Post Traumatic Stress Disorder and Insomnia, has completed, sponsored by Palo Alto Veterans Institute for Research.
- COMPLETED
- Registry status
- NA
- Development phase
- 49 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this two-arm pilot randomized controlled trial is to test a behavioral intervention that integrates three evidence-based cognitive behavioral interventions (written exposure therapy; WET, cognitive behavioral therapy for insomnia; CBT-I, and cognitive behavioral therapy for nightmares; CBT-N) among firefighters. The main questions it aims to answer are: * Is the behavioral intervention feasible, acceptable, and effective in reducing symptoms of posttraumatic stress, insomnia, and nightmares? * What is the efficacy of efficient treatment vs. delayed treatment (2-4 week waitlist) in reducing symptoms of posttraumatic stress, insomnia, and nightmares? We will beta test the intervention in 1-2 groups of 3-5 firefighters. Then we will randomize 50 participants to immediate or delayed (2-4 week waitlist) treatment. Consented participants will: * Complete self-report and interview measures assessing posttraumatic stress disorder, insomnia (PTSD), and nightmares * Attend an individual treatment orientation session * Attend a 4-day (\~3 hours per day over 4 consecutive days) group treatment that integrates WET, CBT-I, and CBT-N * Attend an individual booster session held approximately one week later * Complete self-report measures before, during, and after treatment, and at a 3-month follow up assessment and a clinical interview before and after treatment to assess program efficacy.
Primary Outcome
The CAPS-5 is a structured clinical interview that assesses the presence and severity of PTSD symptoms.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Behavioral Therapy for Nightmares (CBTn)
- BEHAVIORAL Written Exposure Therapy (WET)
- BEHAVIORAL Waitlist
- BEHAVIORAL Cognitive Behavioral Therapy for Insomnia (CBTi)
Study Locations (1)
Missouri
- NDRI_USA - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 49 participants |
| Start Date | 2023-12-01 |
| Est. Completion | 2025-01-01 |
| Phase | NA |
What the finished NCT05950035 record still lists
NCT05950035 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (93% lower).
The record links to 3 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 4 interventions - of which Cognitive Behavioral Therapy for Nightmares (CBTn) is the first listed.
NCT05950035 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT05950035 about?
NCT05950035 is a clinical study titled "An Efficient Treatment for Posttraumatic Injury for Firefighters". The goal of this two-arm pilot randomized controlled trial is to test a behavioral intervention that integrates three evidence-based cognitive behavioral interventions (written exposure therapy; WET, cognitive behavioral therapy for insomnia; CBT-I, and cognitive behavioral therapy for nightmares; C...
What is the current status of trial NCT05950035?
This trial is currently completed. It is a NA study. The enrollment target is 49 participants. The study started on 2023-12-01. Estimated completion is 2025-01-01.
What conditions does trial NCT05950035 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Insomnia, Nightmare.
What interventions are being tested in trial NCT05950035?
The interventions under investigation include: Cognitive Behavioral Therapy for Nightmares (CBTn) (BEHAVIORAL), Written Exposure Therapy (WET) (BEHAVIORAL), Waitlist (BEHAVIORAL), Cognitive Behavioral Therapy for Insomnia (CBTi) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05950035?
This trial is sponsored by Palo Alto Veterans Institute for Research, which has 35 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05950035 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Post Traumatic Stress Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05950035's enrollment target sits among peer trials
49 181st of 262 higher than 82 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Exploring Virtual Reality Adventure Training Exergaming
RECRUITING · NA
-
CRISOL Mente: A Multilevel Community Intervention to Reduce Mental Health Disparities Among Latinos
RECRUITING · NA
-
TMS-fNIRS Personalized Dosing
RECRUITING · NA
-
Targeting the Default Mode Network: A TMS-fMRI Study
RECRUITING · NA
-
The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans
RECRUITING · NA
-
Fear and Avoidance in PTSD Patients
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02704858 · 49 participants · Phase 1
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma
- NCT03516708 · 49 participants · Phase 1
Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer
- NCT03692429 · 49 participants · Phase 1
alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells
- NCT04329494 · 49 participants · Phase 1
PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI